메뉴 건너뛰기




Volumn 75, Issue 1-2, 1997, Pages 59-68

Increased expression of B7-1 costimulatory molecule on cerebrospinal fluid cells of patients with multiple sclerosis and infectious central nervous system disease

Author keywords

B7; cerebrospinal fluid; costimulatory molecules; flow cytometry; multiple sclerosis

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN;

EID: 0030996263     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(96)00234-2     Document Type: Article
Times cited : (32)

References (56)
  • 1
    • 0028237348 scopus 로고
    • CD28-B7 interactions in T-cell activation
    • Allison, J.P. (1994) CD28-B7 interactions in T-cell activation. Curr. Opin. Immunol. 6, 414-419.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 414-419
    • Allison, J.P.1
  • 2
    • 0023427668 scopus 로고
    • The multiple causes of multiple sclerosis: The importance of age of infections in childhood
    • Alvord, Jr, E.C., Jahnke, U., Fischer, E.H. et al. (1987) The multiple causes of multiple sclerosis: The importance of age of infections in childhood. J. Child Neurol. 2, 313-321.
    • (1987) J. Child Neurol. , vol.2 , pp. 313-321
    • Alvord E.C., Jr.1    Jahnke, U.2    Fischer, E.H.3
  • 3
    • 0027313558 scopus 로고
    • Viral infections trigger multiple sclerosis relapses: A prospective seroepidemiological study
    • Andersen, O., Lygner, P.-E., Bergström, T. et al. (1993) Viral infections trigger multiple sclerosis relapses: A prospective seroepidemiological study. J. Neurol. 240, 417-422.
    • (1993) J. Neurol. , vol.240 , pp. 417-422
    • Andersen, O.1    Lygner, P.-E.2    Bergström, T.3
  • 4
    • 0027362823 scopus 로고
    • B70 antigen is a second ligand for CTLA-4 and CD28
    • Azuma, M., Ito, D., Yagita, H. et al. (1993a) B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366, 76-79.
    • (1993) Nature , vol.366 , pp. 76-79
    • Azuma, M.1    Ito, D.2    Yagita, H.3
  • 6
    • 0027511603 scopus 로고
    • Functional expression of B7/BB1 on activated T lymphocytes
    • Azuma, M., Yssel, H., Phillips, J.H. et al. (1993e) Functional expression of B7/BB1 on activated T lymphocytes. J. Exp. Med. 177, 845-850.
    • (1993) J. Exp. Med. , vol.177 , pp. 845-850
    • Azuma, M.1    Yssel, H.2    Phillips, J.H.3
  • 7
    • 0027451433 scopus 로고
    • B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance
    • Boussiotis, V.A., Freeman, G.J., Gray, G. et al. (1993) B7 but not intercellular adhesion molecule-1 costimulation prevents the induction of human alloantigen-specific tolerance. J. Exp. Med. 178, 1753-1763.
    • (1993) J. Exp. Med. , vol.178 , pp. 1753-1763
    • Boussiotis, V.A.1    Freeman, G.J.2    Gray, G.3
  • 8
    • 0025735632 scopus 로고
    • The cell biology of antigen processing and presentation
    • Brodsky, F.M. and Guagliardi, L.E. (1991) The cell biology of antigen processing and presentation. Annu. Rev. Immunol. 9, 707-744.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 707-744
    • Brodsky, F.M.1    Guagliardi, L.E.2
  • 9
    • 0025334064 scopus 로고
    • Tolerance in transgenic mice expressing major histocompatibility molecules extrathymically on pancreatic cells
    • Burkly, L.C., Lo, D. and Flavell, R.A. (1990) Tolerance in transgenic mice expressing major histocompatibility molecules extrathymically on pancreatic cells. Science 248, 1364-1368.
    • (1990) Science , vol.248 , pp. 1364-1368
    • Burkly, L.C.1    Lo, D.2    Flavell, R.A.3
  • 10
    • 0022577031 scopus 로고
    • Viral infections in patients with multiple sclerosis and HLA-DR matched controls
    • Compston, D.A.S., Vakarelis, B.N., McDonald, P.W.I. et al. (1986) Viral infections in patients with multiple sclerosis and HLA-DR matched controls. Brain 109, 325-344.
    • (1986) Brain , vol.109 , pp. 325-344
    • Compston, D.A.S.1    Vakarelis, B.N.2    McDonald, P.W.I.3
  • 11
    • 0028999041 scopus 로고
    • Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation
    • Cross, A.H., Girard, T.J., Giacoletto, K.S. et al. (1995) Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation. J. Clin. Invest. 95, 2783-2789.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2783-2789
    • Cross, A.H.1    Girard, T.J.2    Giacoletto, K.S.3
  • 12
    • 0024435583 scopus 로고
    • Antigen-specific suppressor T lymphocytes in man
    • Damle, N.K. and Engleman, E.G. (1989) Antigen-specific suppressor T lymphocytes in man. Clin. Immunol. Immunopathol. 53(Suppl), S17-S24.
    • (1989) Clin. Immunol. Immunopathol. , vol.53 , Issue.SUPPL.
    • Damle, N.K.1    Engleman, E.G.2
  • 13
    • 0021035361 scopus 로고
    • Alloantigen-specific cytotoxic and suppressor T lymphocytes are derived from phenotypically distinct precursors
    • Damle, N.K., Mohagheghpour, N., Hansen, J.A. and Engleman, E.G. (1983) Alloantigen-specific cytotoxic and suppressor T lymphocytes are derived from phenotypically distinct precursors. J. Immunol. 131, 2296-2300.
    • (1983) J. Immunol. , vol.131 , pp. 2296-2300
    • Damle, N.K.1    Mohagheghpour, N.2    Hansen, J.A.3    Engleman, E.G.4
  • 14
    • 0028964455 scopus 로고
    • The costimulatory molecule B7 is expressed on human microglia in culture and in multiple sclerosis acute lesions
    • de Simone, R., Giampaolo, A., Giometto, B. et al. (1995) The costimulatory molecule B7 is expressed on human microglia in culture and in multiple sclerosis acute lesions. J. Neuropathol. Exp. Neurol. 54, 175-187.
    • (1995) J. Neuropathol. Exp. Neurol. , vol.54 , pp. 175-187
    • De Simone, R.1    Giampaolo, A.2    Giometto, B.3
  • 15
    • 0025950146 scopus 로고
    • Selective induction of B7/BB-1 on interferon-γ stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway
    • Freedman, A.S., Freeman, G.J., Rhynhart, K. and Nadler, L.M. (1991) Selective induction of B7/BB-1 on interferon-γ stimulated monocytes: A potential mechanism for amplification of T cell activation through the CD28 pathway. Cell Immunol. 137, 429-437.
    • (1991) Cell Immunol. , vol.137 , pp. 429-437
    • Freedman, A.S.1    Freeman, G.J.2    Rhynhart, K.3    Nadler, L.M.4
  • 16
    • 0024444165 scopus 로고
    • B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells
    • Freeman, G.J., Freedman, A.S., Segil, J.M. et al. (1989) B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells. J. Immunol. 143, 2714-2722.
    • (1989) J. Immunol. , vol.143 , pp. 2714-2722
    • Freeman, G.J.1    Freedman, A.S.2    Segil, J.M.3
  • 17
    • 0027767762 scopus 로고
    • Cloning of B7-2: A CTLA-4 counter-receptor that costimulates human T cell proliferation
    • Freeman, G.J., Gribben, J.G., Boussiotis, V.A. et al. (1993) Cloning of B7-2: A CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 262, 909-911.
    • (1993) Science , vol.262 , pp. 909-911
    • Freeman, G.J.1    Gribben, J.G.2    Boussiotis, V.A.3
  • 18
    • 0027284230 scopus 로고
    • Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation
    • Gimmi, C.D., Freeman, G.J., Gribben, J.G. et al. (1993) Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc. Natl. Acad. Sci. USA 90, 6586-6590.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6586-6590
    • Gimmi, C.D.1    Freeman, G.J.2    Gribben, J.G.3
  • 19
    • 0025947446 scopus 로고
    • B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2
    • Gimmi, C.D., Freeman, G.J., Gribben, J.G. et al. (1991) B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. Proc. Natl. Acad. Sci. USA 88, 6575-6579.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6575-6579
    • Gimmi, C.D.1    Freeman, G.J.2    Gribben, J.G.3
  • 20
    • 0028365499 scopus 로고
    • Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor a leads to autoimmunity in transgenic mice
    • Guerder, S., Picarella, D.E., Linsley, P.S. and Flavell, R.A. (1994) Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor a leads to autoimmunity in transgenic mice. Proc. Natl. Acad. Sci. USA 91, 5138-5142.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5138-5142
    • Guerder, S.1    Picarella, D.E.2    Linsley, P.S.3    Flavell, R.A.4
  • 21
    • 0023222903 scopus 로고
    • Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfectious encephalomyelitis
    • Hafler, D.A., Benjamin, D.S., Burks, J. and Weiner, H.L. (1987) Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfectious encephalomyelitis. J. Immunol. 139, 68-72.
    • (1987) J. Immunol. , vol.139 , pp. 68-72
    • Hafler, D.A.1    Benjamin, D.S.2    Burks, J.3    Weiner, H.L.4
  • 22
    • 0026537347 scopus 로고
    • CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
    • Harding, F.A., McArthur, J.G., Gross, J.A. et al. (1992) CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356, 607-609.
    • (1992) Nature , vol.356 , pp. 607-609
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3
  • 23
    • 0026688158 scopus 로고
    • Autoimmune diabetes as a consequence of locally produced interleukin-2
    • Heath, W.R., Allison, J., Hoffmann, M.W. et al. (1992) Autoimmune diabetes as a consequence of locally produced interleukin-2. Nature 359, 547-549.
    • (1992) Nature , vol.359 , pp. 547-549
    • Heath, W.R.1    Allison, J.2    Hoffmann, M.W.3
  • 25
    • 0028868424 scopus 로고
    • CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system
    • Khoury, S.J., Akalin, E., Chandraker, A. et al. (1995) CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system. J. Immunol. 155, 4521-4524.
    • (1995) J. Immunol. , vol.155 , pp. 4521-4524
    • Khoury, S.J.1    Akalin, E.2    Chandraker, A.3
  • 26
    • 0029120245 scopus 로고
    • CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
    • Krummel, M.F. and Allison, J.P. (1995) CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182, 459-465.
    • (1995) J. Exp. Med. , vol.182 , pp. 459-465
    • Krummel, M.F.1    Allison, J.P.2
  • 27
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
    • Kuchroo, V.K., Prabhu Das, M., Brown, J.A. et al. (1995) B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy. Cell 80, 707-718.
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Prabhu Das, M.2    Brown, J.A.3
  • 28
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke, J.F. (1983) Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology 33, 1444-1452.
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 29
    • 0027595079 scopus 로고
    • Identifying strategies for immune intervention
    • Lanzavecchia, A. (1993) Identifying strategies for immune intervention. Science 260, 937-944.
    • (1993) Science , vol.260 , pp. 937-944
    • Lanzavecchia, A.1
  • 30
    • 0018422657 scopus 로고
    • Chronic relapsing experimental allergic encephalomyelitis. Clinicopathological comparison with multiple sclerosis
    • Lassmann, H. and Wisniewsky, H.M. (1979) Chronic relapsing experimental allergic encephalomyelitis. Clinicopathological comparison with multiple sclerosis. Arch. Neurol. 36, 490-497.
    • (1979) Arch. Neurol. , vol.36 , pp. 490-497
    • Lassmann, H.1    Wisniewsky, H.M.2
  • 31
    • 0015873738 scopus 로고
    • The changing frequency of multiple sclerosis in Israel
    • Leibowitz, U., Kahana, E., Israel, J. and Alter, M. (1973) The changing frequency of multiple sclerosis in Israel. Arch. Neurol. 29, 107-110.
    • (1973) Arch. Neurol. , vol.29 , pp. 107-110
    • Leibowitz, U.1    Kahana, E.2    Israel, J.3    Alter, M.4
  • 32
    • 0027427549 scopus 로고
    • T cell co-stimulation and in vivo tolerance
    • Lenschow, D.J. and Bluestone, J.A. (1993) T cell co-stimulation and in vivo tolerance. Curr. Opin. Immunol. 5, 747-752.
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 747-752
    • Lenschow, D.J.1    Bluestone, J.A.2
  • 33
    • 0024506159 scopus 로고
    • Regulation of lymphokine messenger RNa stability by a surface-mediated T cell activation pathway
    • Lindsten, T., June, C.H., Ledbetter, J.A. et al. (1989) Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science 244, 339-343.
    • (1989) Science , vol.244 , pp. 339-343
    • Lindsten, T.1    June, C.H.2    Ledbetter, J.A.3
  • 34
    • 0027282960 scopus 로고
    • Characterization of CTLA-4 structure and expression on human T cells
    • Lindsten, T., Lee, K.P., Harris, E.S. et al. (1993) Characterization of CTLA-4 structure and expression on human T cells. J. Immunol. 151, 3489-3499.
    • (1993) J. Immunol. , vol.151 , pp. 3489-3499
    • Lindsten, T.1    Lee, K.P.2    Harris, E.S.3
  • 35
    • 0025963594 scopus 로고
    • Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
    • Linsley, P.S., Brady, W., Grosmaire, L. et al. (1991) Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J. Exp. Med. 173, 721-730.
    • (1991) J. Exp. Med. , vol.173 , pp. 721-730
    • Linsley, P.S.1    Brady, W.2    Grosmaire, L.3
  • 36
    • 0028675006 scopus 로고
    • Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but different kinetics to CD28 and CTLA-4 receptors
    • Linsley, P.S., Greene, J.L., Brady, W. et al. (1994) Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but different kinetics to CD28 and CTLA-4 receptors. Immunity 1, 793-801.
    • (1994) Immunity , vol.1 , pp. 793-801
    • Linsley, P.S.1    Greene, J.L.2    Brady, W.3
  • 37
    • 0027403299 scopus 로고
    • The role of the CD28 receptor during T cell responses to antigen
    • Linsley, P.S. and Ledbetter, J.A. (1993) The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol. 11, 191-212.
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 191-212
    • Linsley, P.S.1    Ledbetter, J.A.2
  • 38
    • 0019932314 scopus 로고
    • In vitro regulation of immunoglobulin synthesis by T-cell subpopulations defined by a new human T-cell antigen (9.3)
    • Lum, L.G., Orcutt, T.N., Seigneuret, M.C. and Hansen, J.A. (1982) In vitro regulation of immunoglobulin synthesis by T-cell subpopulations defined by a new human T-cell antigen (9.3). Cell Immunol. 72, 122-129.
    • (1982) Cell Immunol. , vol.72 , pp. 122-129
    • Lum, L.G.1    Orcutt, T.N.2    Seigneuret, M.C.3    Hansen, J.A.4
  • 40
    • 0024976414 scopus 로고
    • Tolerance of class I histocompatibility antigens expressed extrathymically
    • Morahan, G., Allison, J. and Miller, J.F.A.P. (1989) Tolerance of class I histocompatibility antigens expressed extrathymically. Nature 339, 622-624.
    • (1989) Nature , vol.339 , pp. 622-624
    • Morahan, G.1    Allison, J.2    Miller, J.F.A.P.3
  • 41
    • 0024511201 scopus 로고
    • An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness
    • Mueller, D.L., Jenkins, M.K. and Schwartz, R.H. (1989) An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness. J. Immunol. 142, 2617-2628.
    • (1989) J. Immunol. , vol.142 , pp. 2617-2628
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 42
    • 0020686503 scopus 로고
    • New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
    • Poser, C.M., Paty, D.W., Scheinberg, L. et al. (1983) New diagnostic criteria for multiple sclerosis: Guidelines for research protocols. Ann. Neurol. 13, 227-231.
    • (1983) Ann. Neurol. , vol.13 , pp. 227-231
    • Poser, C.M.1    Paty, D.W.2    Scheinberg, L.3
  • 43
    • 0028785417 scopus 로고
    • Distinct roles for B7-1 (CD80) and B7-2 (CD86) in the initiation of experimental allergic encephalomyelitis
    • Racke, M.K., Scott, D.E., Quigley, L. et al. (1995) Distinct roles for B7-1 (CD80) and B7-2 (CD86) in the initiation of experimental allergic encephalomyelitis. J. Clin. Invest. 96, 2195-2203.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2195-2203
    • Racke, M.K.1    Scott, D.E.2    Quigley, L.3
  • 44
    • 0025358777 scopus 로고
    • Autoimmune diseases: The failure of self tolerance
    • Sinha, A.A., Lopez, M.T. and McDevitt, H.O. (1990) Autoimmune diseases: The failure of self tolerance. Science 248, 1380-1388.
    • (1990) Science , vol.248 , pp. 1380-1388
    • Sinha, A.A.1    Lopez, M.T.2    McDevitt, H.O.3
  • 45
    • 0025748806 scopus 로고
    • Signal transduction by the CD2 antigen in T cells and natural killer cells: Requirement for expression of a functional T cell receptor or binding of antibody Fc to the Fc receptors, FcγRIIIa (CD16)
    • Spruyt, L.L., Glennie, M.J., Beyers, A.D. and Williams, A.F. (1991) Signal transduction by the CD2 antigen in T cells and natural killer cells: Requirement for expression of a functional T cell receptor or binding of antibody Fc to the Fc receptors, FcγRIIIA (CD16). J. Exp. Med. 174, 1407-1415.
    • (1991) J. Exp. Med. , vol.174 , pp. 1407-1415
    • Spruyt, L.L.1    Glennie, M.J.2    Beyers, A.D.3    Williams, A.F.4
  • 46
    • 0028793468 scopus 로고
    • Lymphocyte phenotype and subset distribution in normal cerebrospinal fluid
    • Svenningsson, A., Andersen, O., Edsbagge, M. and Stemme, S. (1995) Lymphocyte phenotype and subset distribution in normal cerebrospinal fluid. J. Neuroimmunol. 63, 39-46.
    • (1995) J. Neuroimmunol. , vol.63 , pp. 39-46
    • Svenningsson, A.1    Andersen, O.2    Edsbagge, M.3    Stemme, S.4
  • 47
    • 0027242269 scopus 로고
    • Adhesion molecule expression on cerebrospinal fluid T lymphocytes. Evidence for common recruitment mechanisms in multiple sclerosis, aseptic meningitis, and normal controls
    • Svenningsson, A., Hansson, G.K., Andersen, O. et al. (1993) Adhesion molecule expression on cerebrospinal fluid T lymphocytes. Evidence for common recruitment mechanisms in multiple sclerosis, aseptic meningitis, and normal controls. Ann. Neurol. 34, 155-161.
    • (1993) Ann. Neurol. , vol.34 , pp. 155-161
    • Svenningsson, A.1    Hansson, G.K.2    Andersen, O.3
  • 48
    • 0024792513 scopus 로고
    • Biology of natural killer cells
    • Trinchieri, G. (1989) Biology of natural killer cells. Adv. Immunol. 47, 187-376.
    • (1989) Adv. Immunol. , vol.47 , pp. 187-376
    • Trinchieri, G.1
  • 49
    • 0027423226 scopus 로고
    • + naive T cells can be efficiently activated by remote co-stimulation with B7
    • + naive T cells can be efficiently activated by remote co-stimulation with B7. Int. Immunol. 5, 1483-1487.
    • (1993) Int. Immunol. , vol.5 , pp. 1483-1487
    • Van De Velde, H.1    Lorré, K.2    Bakkus, M.3
  • 50
    • 0025314483 scopus 로고
    • The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells
    • van Seventer, G.A., Shimizu, Y., Morgan, K.J. and Shaw, S. (1990) The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells. J. Immunol. 144, 4579-4586.
    • (1990) J. Immunol. , vol.144 , pp. 4579-4586
    • Van Seventer, G.A.1    Shimizu, Y.2    Morgan, K.J.3    Shaw, S.4
  • 51
    • 0027530310 scopus 로고
    • In situ expression of B7/BB1 on antigen-presenting cells and activated B cells: An immunohistochemical study
    • Vandenberghe, P., Delabie, J., de, B.M. et al. (1993) In situ expression of B7/BB1 on antigen-presenting cells and activated B cells: An immunohistochemical study. Int. Immunol. 5, 317-321.
    • (1993) Int. Immunol. , vol.5 , pp. 317-321
    • Vandenberghe, P.1    Delabie, J.2    De, B.M.3
  • 52
    • 0024146202 scopus 로고
    • The developmental biology of T lymphocytes
    • von Boehmer, H. (1993) The developmental biology of T lymphocytes. Annu. Rev. Immunol. 6, 309-326.
    • (1993) Annu. Rev. Immunol. , vol.6 , pp. 309-326
    • Von Boehmer, H.1
  • 53
    • 0028791059 scopus 로고
    • Lymphoproliferative disorder with early lethality in mice deficient in Ctla-4
    • Waterhouse, P., Penninger, J.M., Timms, E. et al. (1995) Lymphoproliferative disorder with early lethality in mice deficient in Ctla-4. Science 270, 985-987.
    • (1995) Science , vol.270 , pp. 985-987
    • Waterhouse, P.1    Penninger, J.M.2    Timms, E.3
  • 55
    • 0028578704 scopus 로고
    • B7/BB-1 antigen expression on adult human microglia studied in vitro and in situ
    • Williams, K., Ulvestad, E. and Antel, J.P. (1994) B7/BB-1 antigen expression on adult human microglia studied in vitro and in situ. Eur. J. Immunol. 24, 3031-3037.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 3031-3037
    • Williams, K.1    Ulvestad, E.2    Antel, J.P.3
  • 56
    • 0028809507 scopus 로고
    • Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
    • Windhagen, A., Newcombe, J., Dangond, F. et al. (1995) Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J. Exp. Med. 182, 1985-1996.
    • (1995) J. Exp. Med. , vol.182 , pp. 1985-1996
    • Windhagen, A.1    Newcombe, J.2    Dangond, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.