Permanent and specific transplantation tolerance induced by a nonmyeloablative treatment to a wide variety of allogeneic tissues: I. Induction of tolerance by a short course of total lymphoid irradiation and selective elimination of the donor-specific host lymphocytes

Transplantation

Volumn 63, Issue 10, 1997, Pages 1394-1399

  Prigozhina, Tatyana B ^a   Gurevitch, Olga ^a   Zhu, Jun ^a   Slavin, Shimon ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CYCLOPHOSPHAMIDE; IMMUNOSUPPRESSIVE AGENT;

ALLOGENIC BONE MARROW TRANSPLANTATION; ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHIMERA; CONTROLLED STUDY; FEMALE; GRAFT SURVIVAL; HEART GRAFT; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; LYMPH NODE IRRADIATION; LYMPHOCYTE DEPLETION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN ALLOGRAFT; STROMA CELL;

ANIMALS; BONE MARROW PURGING; BONE MARROW TRANSPLANTATION; CYCLOPHOSPHAMIDE; EPITOPES; FEMALE; HEART TRANSPLANTATION; HISTOCOMPATIBILITY ANTIGENS; IMMUNE TOLERANCE; IMMUNOCOMPETENCE; IMMUNOSUPPRESSIVE AGENTS; LYMPHOID TISSUE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED CBA; T-LYMPHOCYTES; TRANSPLANTATION, HOMOLOGOUS;

EID: 0030995697     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199705270-00004     Document Type: Article

References (34)

1. Papadakis V, Mackinnon S, Kernan NA. Differential effect of pre-transplant cytoreduction on recovery of day zero host circulating cells. Bone Marrow Transplant 1994; 14: 623.
2. Truitt RL, Atasoylu AA. Impact of pretransplant conditioning and donor T-cells on chimerism, graft-versus-host disease, graft-versus-leukemia reactivity, and tolerance after bone marrow transplantation. Blood 1991; 77: 2515.
3. van-Bekkum DW, Hagenbeek A. Immunohematological aspects of total body irradiation and bone marrow transplantation for treatment of leukemia. Radiother Oncol 1990; 18 (suppl 1): 30.
4. Reisner Y, Martelli MF. Bone marrow transplantation across HLA barriers by increasing the number of transplanted cells. Immunol Today 1995; 16: 437.
5. Sachs DH. CCETS Basic Science Lecture. Transplantation tolerance. Ann Thorac Surg 1993; 56: 1221.
6. Ildstad ST, Sachs DH. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature 1984; 307: 168.
7. Tomita Y, Khan A, Sykes M. Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen. J Immunol 1994; 153: 1087.
8. Tomita Y, Sachs DH, Khan A, Sykes M. Additional monoclonal antibody (mAb) injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mAbs and 3-Gy whole body irradiation. Transplantation 1996; 61: 469.
9. Bachar-Lustig E, Rachamim N, Li H-W, Lan F, Reisner Y. Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice. Nat Med 1986; 12: 1268.
10. Slavin S. Total lymphoid irradiation. Immunol Today 1987; 3: 88.
11. Zan-Bar I, Slavin S, Strober S. Induction and mechanism of tolerance to bovine serum albumin in mice given total lymphoid irradiation (TLI). J Immunol 1978; 121: 1400.
12. Slavin S, Yatziv S, Zan-Bar I, Fuks Z, Kaplan HS, Strober S. Nonspecific and specific immunosuppression by total lymphoid irradiation. In: Fougereau M, Dausset J, eds. Progress in immunology. London: Academic Press, 1980; 4: 1160.
13. Barzilay M, Slavin S, Zan-Bar I. Resistance of T suppressor cells to cyclophosphamide administration in total-lymphoid-irradiated mice. Transplantation 1983; 35: 412.
14. Weigensberg M, Morecki S, Weiss L, Fuks Z, Slavin S. Suppression of cell mediated immune responses following total lymphoid irradiation (TLI): 1. Characterization of suppressor cell of the mixed lymphocyte reaction. J Immunol 1984; 132: 971.
15. Morecki S, Weigensberg M, Slavin S. Lectin separation of non-lymphoid suppressor cells induced by total lymphoid irradiation. Eur J Immunol 1985; 15: 138.
16. Slavin S, Or R, Naparstek E, et al. New approaches for prevention of rejection and graft-vs.-host disease in clinical bone marrow transplantation (BMT). Isr J Med Sci 1986; 22: 264.
17. Slavin S, Strober S, Fuks Z, Kaplan HS. Induction of specific tissue transplantation tolerance using fractionated total lymphoid irradiation in adult mice: long-term survival of allogeneic bone marrow and skin grafts. J Exp Med 1977; 146: 34.
18. Chernyakhovskaya IY, Nagurskaya EV, Shaposhnikova GB, Prigozhina TB, Fontalin LN. Tolerance to allogeneic and to xenogeneic heart grafts provided by thymectomy of adult mice combined with donor cell and cyclophosphamide inoculation. Transplantation 1980; 29: 409.
19. Morecki S, Leshem B, Eid A, Slavin S. Alloantigen persistence in induction and maintenance of transplantation tolerance. J Exp Med 1987; 165: 1468.
20. Bach JF. The mode of action of immunosuppressive agents. Amsterdam: North-Holland, 1975.
21. Aisenberg AC, Wilkes B. Immunological tolerance induced by cyclophosphamide assayed by plaque spleen cell method. Nature 1967; 213: 498.
22. Paul WE. Fundamental immunology. New York: Raven, 1984.
23. Chernyakhovskaya IY, Prigozhina TB, Nagurskaya EV, Fontalin LN. Immunological status of mice with long-standing allogeneic or xenogeneic neonatal heart grafts. Transplantation 1984; 38: 267.
24. Maeda T, Eto M, Nishimura Y, Kong Y-Y, Nomoto K, Nomoto K. Evidence that donor-specific suppressor cells can be produced independently of the thymus. Transplantation 1994; 57: 461.
25. Chernyakhovskaya IY, Prigozhina TB, Nagurskaya EV, Fontalin LN. Suppressors of graft-versus-graft reaction in tolerance to alloantigens. Byull Eksper Biol Med (in Russian) 1988; 6: 449.
26. Chernyakhovskaya IY, Prigozhina TB, Lyadova EV, Nagurskaya EV, Fontalin LN. Tolerance to xenogeneic heart graft studied by the method of adoptive transfer. Byull Eksper Biol Med (in Russian) 1988; 7: 996.
27. Mayumi H, Himeno K, Shin T, Nomoto K. Drug-induced tolerance to allografts in mice: VI. Tolerance induction in H-2-haplo-type identical strain combinations in mice. Transplantation 1985; 40: 188.
28. Tomita Y, Nomoto K. Comparison of tolerance inducibility to class I or class II antigens between cyclophosphamide (CP)-induced tolerance and transfusion with donor cells: general effectiveness of CP-induced tolerance and difference of skin graft prolongation in each class I antigen-disparate combination. Immunobiology 1992; 186: 282.
29. Maeda T, Eto M, Nishimura Y, Nomoto K, Kong Y-Y, Nomoto K. Role of peripheral hemopoietic chimerism in achieving donor-specific tolerance in adult mice. J Immunol 1993; 150: 753.
30. Slavin S, Reitz B, Bieber CP, Kaplan HS, Strober S. Transplantation tolerance in adult rats using total lymphoid irradiation: permanent survival of skin, heart, and marrow allografts. J Exp Med 1978; 147: 700.
31. Slavin S, Naparstek E, Aker M, et al. The use of total lymphoid irradiation (TLI) for prevention of rejection of T-lymphocyte depleted bone marrow allografts in non-malignant hematological disorders. Transplant Proc 1989; 21: 3053.
32. Slavin S. The use of total lymphoid irradiation (TLI) for the treatment of autoimmune disorders. Isr J Med Sci 1988; 24: 375.
33. Fuks Z, Slavin S. The use of total lymphoid irradiation (TLI) as immunosuppressive therapy for organ allotransplantation and autoimmune diseases. Int J Radiat Oncol Biol Phys 1981; 7: 79.
34. Soiffer RJ, Mauch P, Tarbell NJ, et al. Total lymphoid irradiation to prevent rejection in recipients of HLA non-identical T-cell depleted allogeneic marrow. Bone Marrow Transplant 1991; 7: 23.