Population based study of prevalence of islet cell autoantibodies in monozygotic and dizygotic Danish twin pairs with insulin dependent diabetes mellitus

British Medical Journal

Volumn 314, Issue 7094, 1997, Pages 1575-1579

  Petersen, Jacob S ^a,f   Kyvik, Kirsten O ^c   Bingley, Polly J ^e   Gale, Edwin A M ^e   Green, Anders ^c   Dyrberg, Thomas ^b   Beck Nielsen, Henning ^d  

^a HAGEDORN RESEARCH INSTITUTE   (Denmark)

^b NOVO NORDISK A S   (Denmark)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d ODENSE UNIVERSITY HOSPITAL   (Denmark)

^e ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^f ZYMOGENETICS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; ENZYME ANTIBODY; GLUTAMATE DECARBOXYLASE; INSULIN ANTIBODY; PANCREAS ISLET CELL ANTIBODY;

ANTIBODY DETECTION; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; DENMARK; DIZYGOTIC TWINS; ENVIRONMENTAL FACTOR; HUMAN; INHERITANCE; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MONOZYGOTIC TWINS; POPULATION RESEARCH; PRIORITY JOURNAL;

EID: 0030995671     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.314.7094.1575     Document Type: Article

References (29)

1. Kyvik K, Green A, Nielsen H. Concordance rates of insulin dependent diabetes mellitus. A population based study of young Danish twins. BMJ 1995;311:913-7.
2. Kumar D, Gemayel NS, Deapen D, Kapadia D, Yamashita PH, Lee M, et al. North-America n twins with IDDM: genetic, etiological and clinical significance of disease concordance accordingly to age, zygosity, and the interval after diagnosis in the first twin. Diabetes 1993;42:1352-63.
3. Kaprio J, Tuomilehto J, Koskenvuo M, Romanov K, Reunanen A, Eriksson J, et al. Concordance for type 1 (insulin-dependent) diabetes mellius in a population-based cohort of twins in Finland. Diabetologia 1992;35:1060-7.
4. Verge CF, Gianani R, Yu L, Pietropaolo M, Smith T, Jackson RA, et al. Late progression to diabetes and evidence for chronic B-cell autoimmunity in identical twins of patients with type 1 diabetes. Diabetes 1995;44:1176-9.
5. Soothill JF, Hayward AR, Woods CBS. Paediatric immunology. Oxford: Blackwell, 1993.
6. Ward KP, Galloway WH, Auchterlonie JA. Congenital cytomegalovirus infection and diabetes. Lancet 1979;i:479.
7. Menser MA, Forrest JM, Bransby RD. Rubella infection and diabetes mellitus. Lancet 1978;i:57-60.
8. Dahlquist GG, Ivarsson S, Lindberg B, Forsgren M. Maternal enteroviral infector during pregnancy as a risk factor for childhood IDDM. Diabetes 1995;44:408-13.
9. Kostraba JN, Cruickshanks KJ, Lawler-Heavner J, Jobim LF, Rewers MJ, Gay EC, et al. Early exposure to cow's milk and solid foods in infancy, genetic predisposition, and risk of IDDM. Diabetes 1993;42:288-95.
10. Karjalainen J, Martin JM, Knip M, Ilonen J, Robinson BH, Savilahti E, et al. A bovine albumin peptide as a possible trigger of insulin-dependent diabetes mellitus. N Engl J Med 1992;327:302-7.
11. Gerstein HC. Crow's milk exposure and type I diabetes. Diabetes Care 1994;17:13-9.
12. Riley WJ. A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes. N Engl J Med 1990;323:1167-72.
13. Krischer JP, Schatz D, Riley WJ, Spillar RP, Silverstein JH, Schwartz S. et al. Insulin and islet cell autoantibodies as time-dependent covariatea in the development of insulin-dependent diabetes: a prospective study in relatives. J Clin Endocrinol Metab 1993;7:743-9.
14. Bingley PJ, Christie MR, Bonifacio F, Bonfanti R, Shattock M, Fonte MT, et al. Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relative. Diabetes 1994;43:1304-10.
15. Roll U, Christie MR, Standl E, Ziegler AG. Association of antiGAD antibodies with islet cell antibodies and insulin autoantibodies in first-degree relatives of type 1 diabetic patients. Diabetes 1994;43:154-60.
16. Kulmala P, Petersen JS, Vahasalo P, Karjalainen J, Dyrberg T, Akerblom HK, et al. Life-table analysis of progression to diabetes in siblings of children with IDDM in relation to IDDM associated autoantibodies. Autoimmunity 1995;21:26 (abstract).
17. Leslie RDG, Elliott RB. Early environmental events as a cause of IDDM. Diabetes 1994;43:843-50.
18. Kyvik K, Green A, Beck-Nielsen H. The new Danish twin register; establishment and analysis of twinning rates, Int J Epidemiol 1995;24:589-96.
19. Hange M. The Danish twin register. In: Mednick SA, Baert AE, Bachmann BP, eds. Prospective longitudinal research. An empirical basis for the primary prevention of psychosocial disorders, Oxford: Oxford University Press 1981:217-21.
20. Petersen J, Hejnaes KR, Moody A, Karlsen AE, Marshall MO, Hoier-Madsen M, et al. Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radioligand assay. Diabetes 1994;43:459-67.
21. Karlsen AE, Hagopian WA, Grubin CE, Dube S, Disteche CM, Adler DA, et al. Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10. Proc Natl Acad Sci USA 1991;88:8337-41.
22. Karlsen AE, Hagopian WA, Petersen JS, Boel E, Dvrberg T, Grubin CE, et al. Recombinant glutamic acid decarboxylase (representing the single iosform expressed in human islets) detects IDDM-associated 64,000-Mr autoantibodies. Diabetes 1993;41:1355-9.
23. Bottazzo GF, Gleichman H. Immunology and diabetes workshops: report of the first international workshop on standardisation of cytoplasmic islet cell antibodies. Diabetologia 1986;29:125-6.
24. Hagopian WA, Sanjeevi CB, Kockum I, Landin-Olsson M, Karlsen AE, Sundkvisk G, et al. Glutamate decarboxylase, insulin, and islet cell antibodies and HLA tping to detect diabetes in a general population-based study of Swedish children. J Clin Invest 1995;95:1501-11.
25. Lorenzen T, Pociot F, Haugaard P, Nerup J. Long-term risk of IDDM in first-degree relatives of patiens with IDDM. Diabetologia 1994;37:321-7.
26. Hagopian WA, Karlsen AE, Gottsater A, Landin-Olsson M, Grubin CE, Sundkvist G, et al. Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibodies positivity at onset predicts diabetes type. J Clin Invest 1993;91:368-74.
27. Grubin CE, Daniels T, Toivola B, Landin-Olsson M, Hagopian WA, Li I., et al. A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM. Diabetologia 1994;7:344-50.
28. Wagenknecht LE, Roseman JM, Herman WH. Increased incidence of insulin-dependent diabetes mellitus following an epideinic of coxsackie virus BS. Am J Epidemiol 1991;133:1024-31.
29. Gamble DR, The epidemiology of insulin-dependent diabetes with particular reference to the relationship of virus infection to its aetiology. Epidemiol Rev 1980;2:19-70.