Suppression of substance P biosynthesis in sensory neurons of dorsal root ganglion by prodrug esters of potent peptidylglycine α-amidating monooxygenase inhibitors

Journal of Biological Chemistry

Volumn 272, Issue 23, 1997, Pages 14666-14671

  Jeng, Arco Y ^a   Fujimoto, Roger A ^a   Chou, Mary ^a   Tan, Jenny ^a   Erion, Mark D ^a,b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b Gensia Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMIDATING ENZYME; AMIDE; ESTER DERIVATIVE; GLYCINE; HOMOCYSTEINE; NEUROPEPTIDE; OXYGENASE INHIBITOR; PRODRUG; SUBSTANCE P;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SENSORY NERVE CELL; SPINAL GANGLION;

ANIMALS; ANIMALS, NEWBORN; ASCORBIC ACID; CARCINOMA, MEDULLARY; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; ENZYME INHIBITORS; ESTERS; GANGLIA, SPINAL; GENE EXPRESSION; HOMOCYSTEINE; INDICATORS AND REAGENTS; MIXED FUNCTION OXYGENASES; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; NEURONS, AFFERENT; PRODRUGS; PROTEIN PRECURSORS; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTANCE P; THYROID NEOPLASMS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0030995506     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.23.14666     Document Type: Article

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