Identification and mapping of new chromosomal sites affecting response to β-lactams in Staphylococcus aureus

International Journal of Antimicrobial Agents

Volumn 8, Issue 1, 1997, Pages 13-21

  Vasilieva, Evgenia ^a   Labischinski, Harald ^b   Berger Bächi, Brigitte ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b BAYER AG   (Germany)

Author keywords

ctaA; fem; genetic mapping; methicillin resistance; mutagenesis; SCV

Indexed keywords

BETA LACTAM ANTIBIOTIC; CEFOTAXIME; CEFOXITIN; IMIPENEM; MECILLINAM; METICILLIN; OXACILLIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; CHROMOSOME INSERTION; CHROMOSOME MAP; CONTROLLED STUDY; ELECTRON TRANSPORT; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OPERON; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

EID: 0030995185     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(96)00346-9     Document Type: Article

References (39)

1. Reynolds PE. The essential nature of staphylococcal penicillin-binding proteins. In: Actor P, Daneo-Moore L, Higgins ML, Salton MRJ. Shockman GD (eds) Antibiotic Inhibition of Bacterial Cell Surface Assembly and Function. ASM, Washington DC, 1988. pp. 343-351.
2. Beise F, Labischinski H, Giesbrecht P. Selective inhibition of penicillin-binding proteins and its effects on growth and architecture of Staphylococcus aureus. FEMS Microbiol Lett 1988;55:195-202.
3. Curtis NAC, Hayes MV, Wyke AW, Ward JB. A mutant of Staphylococcus aureus H lacking penicillin-binding protein 4 and transpeptidase activity. FEMS Microbiol Lett 1980;9:263-266.
4. Song MD, Wachi M, Doi M, Ishino F, Matsuhashi M. Evolution of an inducible penicillin-target protein in methicillin-resistant Staphylococcus aureus by gene fusion. FEBS Lett 1987;221:167-171.
5. Tomasz A, Drugeon HB, de Lencastre HM, Jabes D, McDougall L. New mechanism for methicillin resistance in Staphylococcus aureus: clinical isolates that lack the PBP 2a gene and contain normal penicillin-binding proteins with modified penicillin-binding capacity. Antimicrob Agents Chemother 1989;33:1869-1874.
6. Berger-Bächi B, Strässle A, Kayser FH. Natural methicillin resistance in comparison with that selected by in vitro drug exposure in Staphylococcus aureus. J Antimicrob Chemother 1989;23:179-188.
7. Georgopapadakou NH, Cummings LM, La Sala ER, Unowsky J, Pruess DL. Overproduction of penicillin-binding protein 4 in Staphylococcus aureus is associated with methicillin resistance. In: Actor P, Daneo-Moore L, Higgins ML, Salton M, Shockman GD (eds) Antibiotic Inhibition of Bacterial Cell Surface Assembly and Function. ASM, Washington, 1988, pp. 597-602.
8. Chambers HF, Sachdeva MJ, Hackbarth CJ. Kinetics of penicillin binding to penicillin-binding proteins of Staphylococcus aureus. Biochem J 1994;301:139-144.
9. Hackbarth CJ, Kocagoz T, Kocagoz S, Chambers HF. Point mutations in Staphylococcus aureus PBP 2 gene affect penicillin-binding kinetics and are associated with resistance. Antimicrob. Agents Chemother 1995;39:103-106.
10. Berger-Bächi B. Expression of resistance to methicillin. Trends in Microbiol 1994;2:389-393.
11. Berger-Bächi B, Strässle A, Gustafson JE, Kayser FH. Mapping and characterization of multiple chromosomal factors involved in methicillin resistance in Staphylocccus aureus. Antimicrob Agents Chemother 1992;36:1367-1373.
12. Labischinski H. Consequences of the interaction of beta-lactam antibiotics with penicillin binding proteins from sensitive and resistant Staphylococcus aureus strains. Med Microbiol Immunol 1992;181:241-265.
13. de Lencastre H, Tomasz A. Reassessment of the number of auxiliary genes essential for expression of high-level methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother 1994;38:2590-2598.
14. Maidhof H, Reinicke B, Blümel P, Berger-Bächi B, Labischinski H. femA, which encodes a factor essential for expression of methicillin resistance, affects glycine content of peptidoglycan in methicillin-resistant and methicillin-susceptible Staphylococcus aureus strains. J Bacteriol 1991;173:3507-3513.
15. Henze U. Sidow T. Wecke J, Labischinski H, Berger-Bächi B. Influence of femB on methicillin resistance and peptidoglycan metabolism in Staphylococcus aureus. J Bacteriol 1993;175:1612-1620.
16. de Jonge BLM, Sidow T, Chang YS et al. Altered muropeptide composition in Staphylococcus aureus strains with an inactivated femA locus. J Bacteriol 1993;175:2779-2782.
17. Kopp U. Roos M, Wecke G, Labischinski H. Staphylococcal peptidoglycan interpeptide bridge biosynthesis: a novel antistaphylococcal target? Microbial Drug Resistance 1996;2:29-41.
18. Gustafson J, Strässle A, Hächler H, Kayser FH, Berger-Bächi B. The femC locus of Staphylococcus aureus required for methicillin resistance includes the glutamine synthetase operon. J. Bacteriol. 1994;176:1460-1467.
19. Tomasz A. Benefit and risk in the β-lactam antibiotic-resistance strategies of Streptococcus peumoniae and Staphylococcus aureus. Trends in Microbiol 1994;2:380-385.
20. Maki H, Yamaguchi T, Murakami K. Cloning and characterization of a gene affecting the methicillin resistance level and the autolysis rate in Staphylococcus aureus. J Bacteriol 1994;176:4993 - 5000.
21. Novick, RP. Genetic systems in staphylococci. In: Miller JH (ed) Methods in Enzymology, Bacterial Genetic Systems. Academic Press, New York, 1991, pp. 587-636.
22. Youngman P. Plasmid vectors for recovering and exploiting Tn917 transpositions in Bacillus and other Gram-positive bacteria. In: Hardy KG (ed) Plasmids: a Practical Approach. IRL Press. Oxford, Washington DC 1987:79-103.
23. Berger-Bächi B, Kohler ML. A novel site on the chromosome of Staphylococcus aureus influencing the level of methicillin resistance: genetic mapping. FEMS Microbiol. Lett. 1983;20:305-309.
24. Maniatis T, Fritsch EF, Sambrook JE. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratories Press, New York, 1982.
25. Baker CN, Stocker SA, Culver DH. Thornsberry C. Comparison of the E-test to agar dilution, broth microdilution, and agar diffusion susceptibility testing techniques by using a special challenge set of bacteria. J Clin Microbiol 1991;29:533-538.
26. Ausubel FM, Brent R, Kingston RE et al. Current protocols in molecular biology. Greene Publishing Associates, New York. 1987.
27. Goering RV, Duensing TD. Rapid field-inversion gel electrophorcsis in combination with rRNA gene probe in the epidemiological evaluation of staphylococci. J Clin Microbiol 1990;8:426-429.
28. Hächler H, Berger-Bächi B, Kayser FH. Genetic characterization of a Clostridium difficile erythromycin-clindamycin resistance determinant that is transferable to Staphylococcus aureus. Antimicrob Agents Chemother 1987;31:1039-1045.
29. Henze UU, Berger-Bächi B. Staphylococcus aureus penicillin-binding protein 4 and intrinsic β-lactam resistance. Antimicrob Agents Chemother 1995;39:2415-2422.
30. Strandén A, Roos M, Berger-Bächi B. Glutamine synthetase and heteroresistance in methicillin resistant Staphylococcus aureus. Microbial Drug Resistance 1996;2:201-207.
31. Lorow D, Jesse J. MAX efficiency DH10B™ a new host for cloning methylated DNA. Focus 1990:12:19.
32. Sanger R, Nicklen S, Coulson AR. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 1977;74:5463-5467.
33. Pattee AP. Genetic and physical map of Staphylococcus aureus NCTC8325. In: O'Brien SJ (ed) Genetic maps 1993. Cold Spring Harbor Laboratory Press, New York, 1993, pp. 106-113.
34. Berger-Bächi, B, Barberis-Maino, L, Strässle, A, Kayser, FH. FemA, a host-mediated factor essential for methicillin resistance in Staphylococcus aureus: molecular cloning and characterization. Mol Gen Genetics 1989;219:263-269.
35. Berger-Bächi B, Strässle A, Kayser FH. Characterization of an isogenic set of methicillin-resistant and susceptible mutants of Staphylococcus aureus. Eur J Clin Microbiol 1986;5:697-701.
36. Mueller JP, Taber HW. Isolation and sequence of ctaA, a gene required for cytochrome aa3 biosynthesis and sporulation in Bacillus subtilis. J Bacteriol 1989;171:4967-4978.
37. Proctor RA, Vanlangevelde P, Kristjansson M, Maslow JN, Arbeit RD. Persistent and relapsing infections associated with small-colony variants of Staphylococcus aureus. Clin Infect Dis 1995;20:95-102.
38. Barber M. Naturally occurring methicillin-resistant staphylococci. J Gen Microbiol 1964;35:183-190.
39. Berger-Bächi B. Factors affecting methicillin resistance in Staphylococcus aureus. Int J Antimicrob Agents 1995;6:13-21.