Racemic ketamine and S-(+)-ketamine: Cerebrovascular and neuroprotective effects after focal ischaemia;Ketamin-Razemat und S-(+)-Ketamin. Zerebrovaskulare Effekte und Neuroprotektion nach fokaler Ischamie

Anaesthesist

Volumn 46, Issue SUPPL. 1, 1997, Pages

  Werner, C ^a,b   Reeker, W ^a   Engelhard, K ^a   Lu, H ^a   Kochs, E ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

cerebral blood flow, cerebral oxygen consumption; cerebral ischaemia; intracranial pressure; neuronal protection; NMDA antagonists

Indexed keywords

KETAMINE;

BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN METABOLISM; BRAIN PROTECTION; DOG; DRUG EFFECT; HUMAN; INTRACRANIAL PRESSURE; INTRAVENOUS DRUG ADMINISTRATION; ISOMERISM; NONHUMAN; OXYGEN CONSUMPTION; RACEMIC MIXTURE; REVIEW;

EID: 0030995178     PISSN: 00032417     EISSN: None     Source Type: Journal    
DOI: 10.1007/pl00002466     Document Type: Review

References (25)

1. Artru AA, Katz RA (1989) Cerebral blood volume and CSF pressure following administration of ketamine in dogs; modification by pre- or posttreatment with hypocapnia or diazepam. J Neurosurg Anesth 1:8-15
2. Cavazzuti M, Porro CA, Biral GP, Benassi C, Gbarbieri GC (1987) Ketamine effects on local cerebral blood flow and metabolism in the rat. J Cereb Blood Flow Metab 7:806-811
3. Church J, Zeman S, Lodge D (1988) The neuroprotective action of ketamine and MK-801 after transient cerebral ischemia in rats. Anesthesiology 69:702-709
4. Dawson B, Michenfelder JD, Theye RA (1971) Effects of ketamine on canine cerebral blood flow and metabolism: modification by prior administration of thiopental. Anesth Analg 50:443-447
5. Gardner AE, Olson BE, Lichtiger M (1971) Cerebrospinal-fluid pressure during dissociative anesthesia with ketamine. Anesthesiology 35:226-228
6. Gibbs JM (1972) The effect of intravenous ketamine on cerebrospinal fluid pressure. Br J Anaesth 44:1298-1302
7. Herrschaft H, SchmidtH (1973) Das Verhalten der globalen und regionalen Hirndurchblutung unter dem Einfluß von Propanidid, Ketamin und Thiopental-Natrium. Anaesthesist 22:486-495
8. Hoffman WE, Pelligrino D, Werner C, Kochs E, Albrecht RF, Schulte am Esch J (1992) Ketamine decreases plasma catecholamines and improves neurologic outcome from incomplete cerebral ischemia in rats. Anesthesiology 76:755-762
9. Hougaard K, Hansen A, Brodersen P (1974) The effect of ketamine on regional cerebral blood flow in man. Anesthesiology 41:562-567
10. Jensen ML, Auer RN (1988) Ketamine fails to protect against ischemic neuronal necrosis in the rat. Br J Anaesth 61:206-210
11. Kreuscher H, Grote J (1967) Die Wirkung des Phencyclidinderivates Ketamine (Cl 581) auf die Durchblutung und Sauerstoffaufnahme des Gehirns beim Hund. Anaesthesist 16:304-307
12. Mayberg TS, Lam AM, Matta BF, Domino KB, Winn HR (1995) Ketamine does not increase cerebral blood flow velocity or intracranial pressure during isoflurane/nitrous oxide anesthesia in patients undergoing craniotomy. Anesth Analg 81:84-89
13. Oren RE, Rasool MA, Rubinstein EH (1987) Effect of ketamine on cerebral cortical blood flow and metabolism in rabbits. Stroke 18:441-444
14. Pfenninger E, Ahnefeld FW, Grünert A (1985) Untersuchung zum intrakraniellen Druckverhalten unter Ketaminapplikation bei erhaltener Spontanatmung. Anaesthesia 34:191-196
15. Pfenninger E, Dick W, Grünert A, Lotz P (1984) Tierexperimentelle Untersuchung zum intrakraniellen Druckverhalten unter Ketaminapplikation. Anaesthesist 33:82-88
16. Pfenninger E, Reith A (1990) Ketamine and intracranial pressure. In: Domino EF (ed) Status of ketamine in Anesthesiology. NPP Books, pp 109-118
17. Schulte am Esch J, Pfeifer G, Thiemig I, Entzian W (1978) The influence of intravenous anesthetic agents on primarily increased intracranial pressure. Acta Neurochirurgica 45:15-25
18. Schwedler M, Miletich DJ, Albrecht RF (1982) Cerebral blood flow and metabolism following ketamine administration. Can Anaesth Soc J 29:222-226
19. Shapira Y, Artru AA (1992) Ketamine decreases cerebral infarct volume and improves neurological outcome following experimental head trauma in rats. J Neurosurg Anesth 4:231-240
20. Shapira Y, Lam AM, Eng CC, Laohaprasit V, Michel M (1994) Therapeutic time window and dose response of the beneficial effects of ketamine in experimental head injury. Stroke 25:1637-1643
21. Shapiro HM, Wyte SR, Harris AB (1972) Ketamine anaesthesia in patients with intracranial pathology. Br J Anaesth 44:1200-1204
22. Takeshita H, Okuda Y, Sari A(1972) The effects of ketamine on cerebral circulation and metabolism in man. Anesthesiology 36:69-75
23. Wendung WW, Daniels FB,Chen D, Harakal C, Carlsson C (1994) Ketamine directly dilates bovine cerebral arteries by acting as a calcium entry blocker. J Neurosurg Anesth 6:186-192
24. White PF, Way WL, Trevor AJ (1982) Ketamine-its pharmacology and therapeutic uses. Anesthesiology 56:119-136
25. Wyte SR, Shapiro HM, Turner P, Harris AB (1972) Ketamine-induced intracranial hypertension. Anesthesiology 36:174-176