Use of LC-MS/MS to cross-validate a radioimmunoassay for the fibrinogen receptor antagonist, Aggrastat (tirofiban hydrochloride) in human plasma

Journal of Pharmaceutical and Biomedical Analysis

Volumn 15, Issue 5, 1997, Pages 561-569

  Ellis, Joan D ^a   Hand, Elizabeth L ^a   Gilbert, John D ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Aggrastat; Cross validation; Liquid chromatography tanden mass spectrometry; Plasma; Radioimmunoassay; Tirofiban hydrochloride

Indexed keywords

FIBRINOGEN RECEPTOR ANTAGONIST; TIROFIBAN;

ANALYTIC METHOD; ARTICLE; BLOOD ANALYSIS; DRUG DETERMINATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

CALIBRATION; CHROMATOGRAPHY, LIQUID; FIBRINOLYTIC AGENTS; HUMANS; MASS SPECTROMETRY; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RADIOIMMUNOASSAY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TYROSINE;

EID: 0030994808     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(96)01848-1     Document Type: Article

References (21)

1. B. Stein, V. Fuster, D.H. Israel, M. Cohen, L. Badimon, J.J. Badimon and J.H. Chesebro, J. Am. Coll. Cardiol., 14 (1989) 813-836.
2. D.J. Fitzgerald, L. Roy, F. Catella and G.A. Fitzgerald, N. Engl. J. Med., 315 (1986) 983-989.
3. D.J. Fitzgerald, F. Catella, L. Roy and G.A. Fitzgerald, Circulation, 77 (1988) 142-150.
4. C.W. Hamm, R.L. Lorenz, W. Bleifeld, W. Kupper, W. Wober and P.C. Weber, J. Am. Coll. Cardiol., 10 (1987) 998-1004.
5. G.A. Marguerie, E.F. Plow and T.S. Edgington, J. Biol. Chem., 254 (1979) 5357-5363.
6. J. Hawiger, S. Parkinson and S. Timmons, Nature (London), 283 (1980) 195-197.
7. E.I. Peerschke, M.B. Zucker R.A. Grant, J.J. Egan and M.M. Johnson, Blood 55 (1980) 841-847.
8. E. Ruoslahti and M.D. Pierschbacher, Science, 238 (1987) 491-497.
9. G.D. Hartman, M.S. Egbertson, W. Halczenko, W.L. Laswell, M.E. Duggan, R.L. Smith, A.M. Naylor, P.D. Manno, R.J. Lynch, G. Zhang, C.T.-C. Chang and R.J. Gould, J. Med. Chem., 35 (1992) 4640-4642.
10. M.S. Egbertson, C.T.-C. Chang, M.E. Duggan, R.J. Gould, W. Halczenko, G.D. Hartman, W.L. Laswell, J.J. Lynch, Jr., R.J. Lynch, P.D. Manno, A.M. Naylor, J.D. Prugh, D.R. Ramjit, G.R. Sitko, R.S. Smith, L.M. Turchi and G. Zhang, J. Med. Chem., 37 (1994) 2537-2551.
11. J.J. Lynch, Jr., J.J. Cook, G.R. Sitko, M.A. Holahan, D.R. Ramjit, M.J. Mellott, M.T. Stranieri, I.I. Stabilito, G. Zhang, R.J. Lynch, P.D. Manno, C.T.-C. Chang, M.S. Egbertson, W. Halczenko, M.E. Duggan, W.L. Laswell, L.M. Vassallo, J.A. Shafer, P.S. Anderson, P.A. Friedman, G.D. Hartman and R.J. Gould, J. Pharmacol Exp. Ther. 272 (1995) 20-32.
12. F.L. Hand, J.D. Gilbert, A.S. Yuan, T.V. Olah and M. Hichens, J. Pharm. Biomed. Anal, 12 (1994) 1047-1053.
13. J.S. Barrett, G. Murphy, K. Peerlinck, I, DeLepeleire, R.J. Gould, D. Panebianco, E. Hand, H. Deckmyn, J. Vermylen and J. Arnout, Clin. Pharmacol. Ther., 56, (1994) 377-388.
14. J.D. Gilbert, E.L. Hand, D.A. McLoughlin, J.D. Ellis, T.V. Olah, A.S. Yuan and C. Fernandez-Metzler, in E. Reid, H.M. Hill and I.D. Wilson (Eds.) Methodological Surveys in Bioanalysis of Drugs, Vol. 24. Royal Society of Chemistry, Cambridge, 1996, in press.
15. W.J. Dixon, Biometrics, 9 (1953) 74-89.
16. M.T. Gilbert, I. Barinov-Colligon and J.R. Miksic, J. Pharm. Biomed. Anal., 13 (1995) 385-394.
17. T. Roy, J. Pharm. Biomed. Anal., 12 (1994) 1265-1269.
18. H. Fouda, M. Nocerini, R. Schneider and C. Gedutis, J. Am. Soc. Mass Spectrom., 2 (1991) 164-167.
19. J.D. Gilbert, E.L. Hand, A.S. Yuan, T.V. Olah and T.R. Covey, Biol. Mass Spectrom., 21 (1992) 63-68.
20. J.D. Gilbert, T.V. Olah and D.A. McLoughlin, in A.P. Snyder (Ed.) Biochemical and Biotechnological Applications of Electrospray Ionization Mass Spectrometry, ACS Symposia Series No. 619, American Chemical Society, Washington, DC, 1996, pp. 330-350.
21. J.D. Gilbert, T.F. Greber, J.D. Ellis, A. Barrish, T.V. Olah, C. Fernadez-Metzler, A.S. Yuan and C.J. Burke, J. Pharm. Biomed. Anal. 13 (1995) 937-950.