Interlaboratory variation in the detection of clinically significant alloantibodies against human platelet alloantigens

British Journal of Haematology

Volumn 97, Issue 1, 1997, Pages 204-207

  Metcalfe, P ^a   Allen, D ^b   Chapman, J ^c   Ouwehand, W H ^a,d  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^d NHS BLOOD AND TRANSPLANT   (United Kingdom)

Author keywords

anti HPA 1a; antibody detection; human platelet alloantigens; neonatal alloimmune thrombocytopenia

Indexed keywords

ALLOANTIBODY; ALLOANTIGEN; THROMBOCYTE ANTIGEN;

ALLOIMMUNITY; ANTIBODY DETECTION; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LABORATORY TEST; NEWBORN; PRIORITY JOURNAL; QUALITY CONTROL; THROMBOCYTE;

EID: 0030993937     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.9992647.x     Document Type: Article

References (7)

1. Allen, D.L., Chapman, J., Phillips, P.K. & Ouwehand, W.H. (1994) Sensitivity of the platelet immunofluorescence test (PIFT) and the MAIPA assay for the detection of platelet reactive alloantibodies: a report of two U.K. National Platelet Workshop Exercises. Transfusion Medicine, 4, 157-164.
2. Cavanagh, G., Dunn, A.N., Chapman, C.E. & Metcalfe, P. (1997) HPA genotyping by sequence-specific priming (PCR-SSP): a streamlined method for routine investigations. Transfusion Medicine (in press).
3. A1, HPA-1a) form of platelet glycoprotein IIIa from a V gene phage display library. Blood, 86, 4430-4436.
4. Kluter, H., Fehlau, K., Panzer, S., Kirchner, H. & Bein, G. (1996) Rapid typing for human platelet antigen systems-1, -2. -3 and -5 by PCR amplification with sequence specific primers. Vox Sanguinis, 71, 121-125.
5. Peterson, J., Newman, P.J., Visentin, G.P. & Aster, R.H. (1995) A recombinant soluble form of the integrin GPIIb/IIIa spontaneously assumes an active, ligand- binding conformation and is recognised by GPIIb/IIIa specific monoclonal, allo, auto- and drug dependent platelet antibodies. Blood, 86, 278a.
6. von dem Borne, A.E.G. Kr., de Haas, M., Simcek, S., Porcelijn, L. & van der School, C.E. (1996) Platelet and neutrophil alloantigens in clinical medicine. Vox Sanguinis, 70, (Suppl. 3), 34-40.
7. Williamson, L.M., Hackett, G.A., Rennie, J.M., Maciver, C.R., Hadfield, R., Hughes, D. & Palmer, P. (1995) Determination of the natural history of neonatal alloimmune thrombocytopenia (NAITP) by antenatal screening. Blood, 86, 538a.