Differential excretion of leucocyte granule components in inflammatory bowel disease: Implications for pathogenesis

Clinical Science

Volumn 92, Issue 3, 1997, Pages 307-313

  Dwarakanath, A D ^a   Finnie, I A ^a   Beesley, C M ^a   O'Dowd, G M ^a   Nash, J ^a   Tsai, H H ^a   Parker, N ^a   Rhodes, Jonathan M ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Lactoferrin; Mast cell; Myeloperoxidase; Ulcerative colitis

Indexed keywords

LACTOFERRIN; LEUKOCYTE ENZYME; MYELOPEROXIDASE;

ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DIARRHEA; ENTERITIS; FECES; FECES LEVEL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE CRYPT; INTESTINE MUCOSA; LEUKOCYTE; MAJOR CLINICAL STUDY; MAST CELL; PATHOGENESIS; PRIORITY JOURNAL; ULCERATIVE COLITIS;

EID: 0030993834     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0920307     Document Type: Article

References (26)

1. Leddin DJ, Paterson WG, Dacosta LR. Indium-III labelled autologous leukocyte imaging and fecal excretion. Dig Dis Sci 1987; 32: 377-87.
2. Saverymuttu SH, Peters AM, Lavender JP, Pepys MB, Hodgson HJF, Chadwick VS. Assessment of disease activity in ulcerative colitis using indium-III labelled leukocyte excretion in the assessment of disease in Crohn's disease. Gastroenterology 1983; 85: 1333-9.
3. Adeyemi EO and Hodgson HJF. Faecal elastase reflects disease activity in active ulcerative colitis. Scand J Gastroenterol 1992; 27: 139-42.
4. Hemrika MH, Costongs GM, Engles LG, Bos LP, Janson PC, Flendrig JA. Clinical relevance of lysozyme in the faeces. Neth J Med 1989; 34: 174-81.
5. Truelove SC and Witts LJ. Cortisone in ulcerative colitis. Final report on a therapeutic trial. Br Med J 1955; 2: 1041-8.
6. Harvey RF and Bradshaw JM. A simple index of Crohn's disease activity. Lancet 1980; 1: 514.
7. Shannon IL and Frome RP. Enhancement of salivary flow rate and buffering capacity. J Can Dent Assoc 1973; 39: 177-81.
8. Jenkins GN. In: Physiology and biochemistry of the mouth 4th. ed. Oxford: Blackwell, 1978.
9. Klebanoff SJ. In: Everse J, Everse E, Grisham MB eds. Peroxidases in chemistry and biology. Boston: CRC Press, 1992: 1-35.
10. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein determination with Folin-phenol reagent J Biol Chem 1951; 193: 265-75.
11. Wang C-S, Chan W-Y, Kloer UH. Comparative studies on the chemical and immunochemical properties of human milk, human pancreatic juice, and bovine milk lactoferrin. Comp Biochem Physiol 1984; 78: 575-80.
12. Magnuson JS, Henry JF, Yip T-T, Hutchens TW. Structural homology of human, bovine, and porcine milk lactoferrins: evidence for shared antigenic determinants. Pediatr Res 1990;28:176-81.
13. Kuizenga A, van Haeringen NJ, Kijlstra A. Inhibition of hydroxyl radical formation by human tears. Invest Ophthalmol Vis 3d 1987; 28: 205-13.
14. Saito N, Takemori N, Tachibana N, Hayashishita N. Ultrastructural evidence for the origin of mast cells in normal human bone marrow. Am J Haematol 1991; 38: 69-71.
15. Adeyemi EO, Hodgson HJF. Lactoferrin: a correlate of disease activity in inflammatory bowel disease. Eur J Castro Hepatol 1991; 3: 51-6.
16. O'Morain C, Smethurst P, Levi AJ, Peters TJ. Biochemical analysis of enzymatic markers of inflammation in rectal biopsies from patients with ulcerative colitis and Crohn's disease. J Clin Pathol 1983; 36: 1312-16.
17. Henson PM, Henson JE, Fittschen C, Bratton DL, Riches DWH. Degradation and secretion by phagocytic cells. In: Gallin Jl, Goldstein IM, Snyderman R, eds. Inflammation basic principles and clinical correlates. New York: Raven Press, 1992: 511-540.
18. Wright DG, Gallin JI. Secondary responses of human neutrophils. Exocytosis of specific (secondary) granules, by human neutrophils during adherence in vitro and during exudation in vivo. J Immunol 1979; 123: 285-94.
19. Wright DG, Bralove DA, Gallin JI. The differential mobilisation of human neutrophil granules: effects of phorbol myristate acetate and ionophore A23187. Am J Pathol 1977; 87:273-81.
20. Fittschen C, Henson PM. Linkage of azurophil granule secretion in neutrophils to chloride ion transport and endosomal transcytosis. J Clin Invest 1994; 93: 247-55.
21. McCormick BA, Colgan SP, Delp-Archer C, Miller SI, MadaraJL Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils. J Cell Biol 1993; 123: 895-907.
22. Boxer LA, Haak RA, Yang HH, Wolack JB, Whitcomb JA, Butterock CJ, Baehner PJ_ Membrane-bound lactoferrin alters the surface properties of polymorphonudear leucocytes. J Clin Invest 1982; 70: 1047-9.
23. Oseas R, Yang HH, Baehner RL, Boxer LA Lactoferrin: a promoter of polymorphonudear leucocyte adhesiveness. Blood 1981; 57: 939-45.
24. Kurose I, Wolf R, Graiser DN. Lactoferrin-induced microvascular and mucosal injury in rat intestine: role of leucocytes. Gastroenterology 1993; 104: A729.
25. Peen E, Ahmer S, Bodemar G, Ryden B-0, Sjolin C, Tejle K, Skogh T. Antilactoferrin antibodies and other types of ANCA in ulcerative colitis, primary sclerosing cholangitis, and Crohn's disease. Gut 1993; 34: 56-62.
26. Saxon A, Shanahan F, Landers C, Ganz T, Targan S. A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease. J Allergy Clin Immunol 1990; 86: 202-20.