Inhibitory control of neural differentiation in mammalian cells

Development Genes and Evolution

Volumn 207, Issue 1, 1997, Pages 19-28

  Hoodless, Pamela A ^a   Hemmati Brivanlou, Ali ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Activin receptor; BMP; Epidermal induction; Neural induction; P19 cells

Indexed keywords

ACTIVIN; BONE MORPHOGENETIC PROTEIN; CELL RECEPTOR; KERATIN; RETINOIC ACID;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONAL CARCINOMA; EPIDERMIS; MAMMAL CELL; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; XENOPUS;

EID: 0030992561     PISSN: 0949944X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004270050088     Document Type: Article

References (55)

1. Bain G, Ray WJ, Yao M, Gottlieb DI (1994) From embryonal carcinoma cells to neurons: The P19 pathway. BioEssays 16:343-348
2. Beddington RSP (1994) Induction of a second neural axis by the mouse node. Development 120:613-620
3. Dawid IB (1994) Intercellular signaling and gene regulation during early embryogenesis of Xenopus laevis. J Biol Chem 269: 6259-6262
4. Dubus E, Weber K, Osborn M (1983) Monoclonal antibodies specific for glial fibrillary acidic (GFA) protein and for each of the neurofilament triplet polypeptides. Differentiation 25:193-203
5. Evan GI, Lewis GK, Ransay G, Bishop JM (1985) Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol Cell Biol 5:3610-3616
6. Godsave SF, Slack JMW (1989) Clonal analysis of mesoderm induction in Xenopus laevis. Dev Biol 134:486-490
7. Graff JM, Thies RS, Song JJ, Celeste AJ, Melton DA (1994) Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79:169-79
8. Grunz H, Tacke L (1989) Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer. Cell Differ Dev 28:211-218
9. Harland RM (1994) The transforming growth factor β family and induction of the vertebrate mesoderm: Bone morphogenetic proteins are ventral inducers. Proc Natl Acad Sci USA 91: 10243-10246
10. Hashimoto M, Kondo S, Sakurai T, Etoh Y, Shibai H, Muramatsu M (1990) Activin/EDF as an inhibitor of neural differentiation. Biochem Biophys Res Commun 173:193-200
11. Hashimoto M, Nakamura T, Inoue S, Kondo T, Yamamda R, Eto Y, Sugino H, Muramatsu M (1992) Follistatin is a developmentally regulated cytokine in neural differentiation. J Biol Chem 267:7203-7206
12. Hawley SH, Wunnenberg-Stapleton K, Hashimoto C, Laurent MN, Watabe T, Blumberg BW, Cho KW (1995) Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. Genes Dev 9:2923-2935
13. Hemmati-Brivanlou A, Melton DA (1992) A truncated activin receptor dominantly inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359:609-614
14. Hemmati-Brivanlou A, Melton DA (1994) Inhibition of activin signaling promotes neuralization in Xenopus. Cell 77:273-281
15. Hemmati-Brivanlou A, Thomsen GH (1995) Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP-2 and BMP-4. Dev Genet 17:78-89
16. Hemmati-Brivanlou A, Kelly OG, Melton DA (1994) Follistatin, an antagonist of activin is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77:283-295
17. Hotten G, Neidhardt H, Schneider C, Pohl J (1995) Cloning of a new member of the TGF-β family: A putative new activin βc chain. Biochem Biophys Res Commun 206:608-613
18. Kessler DS, Melton DA (1995) Induction of dorsal mesoderm by soluble, mature Vg1 protein. Development 121:2155-2164
19. Kintner CR, Dodd J (1991) Hensen's node induces neural tissue in Xenopus ectoderm. Implications for the action of the organizer in neural induction. Development 113:1495-1506
20. Kondo S, Hashimoto M, Etoh Y, Murata M, Shibai H, Muramatsu M (1989) Identification of the two types of specific receptor for activin/EDF expressed on Friend Leukemia and embryonal carcinoma cells. Biochem Biophys Res Commun 161:1267-1272
21. Kopan R, Fuchs E (1989) A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin. Genes Dev 3:1-15
22. Lamb TM, Knecht AK, Smith WC, Stachel SE, Economides AN, Stahl N, Yancopolous GD (1993) Neural induction by the secreted polypeptide noggin. Science 262:713-718
23. Matzuk MM, Kumar TR, Bradley A (1995a) Different phenotypes for mice deficient in either activins or activin receptor type II. Nature 374:356-360
24. Matzuk MM, Kumar TR, Vassalli A, Bickenbach JR, Roop DR, Jaenisch R, Bradley A (1995b) Functional analysis of activins during mammalian development. Nature 374:354-356
25. McBurney MW (1993) P19 embryonal carcinoma cells. Int J Dev Biol 37:135-140
26. Mishina Y, Suzuki A, Ueno N, Behringer RR (1995) Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis. Genes Dev 15:3027-3037
27. Moll R, Franke WW, Schiller DL (1982) The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 31:11-24
28. Morassutti DJ, Staines WA, Magnuson DSK, Marshall KC, McBurney MW (1994) Murine embryonal carcinoma-derived neurons survive and mature following transplantation into adult rat striatum. Neuroscience 58:753-763
29. Mummery CL, van den Eijnden-van Raaij AJM (1993) Type β transforming growth factors and activins in differentiating embryonal carcinoma cells, embryonic stem cells and early embryonic development. Int J Dev Biol 37:169-182
30. Nye JS, Kopan R, Axel R (1994) An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells. Development 120:2421-2430
31. Oda S, Nishimatsu S, Murakami K, Ueno N (1995) Molecular cloning and functional analysis of a new activin β subunit: A dorsal mesoderm-inducing activity in Xenopus. Biochem Biophys Res Commun 210:581-588
32. Piccolo S, Sasai Y, Lu B, Robertis EM de (1996) Dorsovental patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 86:589-598
33. Rossant J, McBurney MW (1982) The developmental potential of a euploid male teratocarcinoma cell line after blastocyst injection. J Embryol Exp Morphol 70:99-112
34. Rudnicki MA, McBurney MW (1987) Cell culture methods and induction of differentiation of embryonal carcinoma cell lines. In: Robertson EJ (ed) Teratocarcinomas and embryonic stem cells, a practical approach. IRL Press, Oxford, pp 19-50
35. Sasai Y, Lu B, Steinbeisser H, Geissert D, Gont LK, Robertis EM de (1994) Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79:779-790
36. Sasai Y, Lu B, Steinbeisser H, Robertis EM de (1995) Regulation of neural induction by the Chd and BMP-4 antagonistic patterning signals in Xenopus. Nature 376:333-336
37. Sato SM, Sargent TD (1989) Development of neural inducing capacity in dissociated Xenopus embryos. Dev Biol 134:263-266
38. Schmidt JW, Brugge JS, Nelson WJ (1992) pp60src tyrosine kinase modulates P19 embryonal carcinoma cell fate by inhibiting neuronal but not epithelial differentiation. J Cell Biol 116:1019-1033
39. Schubert D, Kimura H, LaCorbiere M, Vaughan J, Karr D, Fischer WH (1990) Activin is a nerve cell survival molecule. Nature 344:868-870
40. Schulte-Merker S, Smith JC, Dale L (1994) Effects of truncated activin and FGF receptors and of follistatin on the inducing activity of BVg1 and activin: does activin play a role on mesoderm induction. EMBO J 13:3533-3541
41. Smith JC (1993) Mesoderm-inducing factors in early vertebrate development. EMBO J 12:4463-4470
42. Spemann H (1938) Embryonic development and induction. Yale University Press, New York
43. Spemann H, Mangold H (1924) Über Induktion von Embryonanlagen durch Implantation artfremder Organisatoren. Arch Mikrosk Anat Entwicklungsmech 100:599-638
44. Suzuki A, Theis RS, Yamaji N, Song JJ, Wozney J, Murakami K, Ueno N (1994) A truncated BMP receptor affects dorsal-ventral patterning in the early Xenopus embryo. Proc Natl Acad Sci USA 91:10255-1259
45. Eijnden-van Raaij AJM van den, Feijen A, Lawson KA, Mummery CL (1992) Differential expression of inhibin subunits and follistatin, but not of activin receptor type II, during early murine embryonic development. Dev Biol 154:356-365
46. Eijnden-van Raaij AJM van den, Achterberg TAE van, Kruijssen CMM van der, Piersma AH, Huylebroeck D, Laat SW de, Mummery CL (1991) Differentiation of aggregated murine P19 embryonal carcinoma cells is induced by a novel visceral endoderm-specific FGF-like factor and inhibited by activin A. Mech Dev 33:157-166
47. Vassalli A, Matzuk MM, Gardner HAR, Lee K-F, Jaenisch R (1994) Activin/inhibin βB subunit gene disruption leads to defects in eyelid development and female reproduction. Genes Dev 8:414-427
48. Vidricaire G, Jardine K, McBurney MW (1994) Expression of the Brachyury gene during mesoderm development in differentiation embryonal carcinoma cell cultures Development 120: 115-122
49. Waddington CH, Schmidt CA (1933) Induction by heteroplastic grafts of the primitive streak in birds. Wilhelm Roux Arch Entwicklungsmech Org 128:522-563
50. Wigler M, Pellicer A, Silverstein S, Axel R, Urlaub G, Chasin L (1979) DNA-mediated transfer of the adenine phosphoribosyl-transferase locus into mammalian cells. Proc Natl Acad Sci USA 76:1373-1376
51. Wilson PA, Hemmati-Brivanlou A (1995) Induction of epidermis and inhibition of neural fate by BMP-4. Nature 376:331-333
52. Winnier G, Blessing M, Labosky PA, Hogan BL (1995) Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev 9:2105-2116
53. Xu RH, Kim J, Taira M, Zhan S, Sredni D, Kung HF (1995) A dominant negative bone morphogenetic protein 4 receptor causes neuralization in Xenopus ectoderm. Biochem Biophys Res Commun 212:212-219
54. Yamashita H, Dijke P ten, Huylebroeck D, Sampath TK, Andries M, Smith JC, Heldin CH, Miyazono K (1995) Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects. J Cell Biol 130: 217-226
55. Zimmerman LB, Jesús-Escobar JM de, Harland RM (1996) The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86:599-606