Intracellular acidosis activates c-Src

American Journal of Physiology - Cell Physiology

Volumn 272, Issue 3 41-3, 1997, Pages

  Yamaji, Yasuyoshi ^a   Tsuganezawa, Hirohiko ^a   Moe, Orson W ^a,b   Alpern, Robert J ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

MCT cells; proximal tubule; tyrosine phosphorylation; vanadate

Indexed keywords

ANIMAL CELL; ARTICLE; CELL PH; ENZYME ACTIVATION; KIDNEY PROXIMAL TUBULE; METABOLIC ACIDOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALIA;

EID: 0030992199     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.272.3.c886     Document Type: Article

References (41)

1. 31P-NMR in vivo measurement of renal intracellular pH: effects of acidosis and K depletion in rats. Am. J. Physiol. 251 (Renal Fluid Electrolyte Physiol. 20): F904-F910, 1986.
2. Alpern, R. J. Nephrology forum: trade-offs in the adaptation to acidosis. Kidney Int. 47: 1205-1215, 1995.
3. c-src. Nature Lond. 349: 172-175, 1991.
4. + exchanger isoform of the renal brush border. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F736-F742, 1993.
5. Chow, L. H., and E. P. Nord. Non-receptor tyrosine kinase expression in rat renal cortex detected by in situ reverse transcription and polymerase chain reaction (Abstract). J. Am. Soc. Nephrol. 3: 484, 1993.
6. Chu, T.-S., H. Tsuganezawa, Y. Peng, A. Cano, M. Yanagisawa, and R. J. Alpern. Role of tyrosine kinase pathways in ETB receptor activation of NHE3. Am. J. Physiol. 271 (Cell Physiol. 40): C763-C771, 1996.
7. Cooper, J. A., and B. Howell. The when and how of src regulation. Cell 73: 1051-1054, 1993.
8. Courtneidge, S. A., R. Dhand, D. Pilat, G. M. Twamley, M. D. Waterfield, and M. F. Roussel. Activation of src family kinases by colony stimulating factor-1, and their association with its receptor. EMBO J. 12: 943-950, 1993.
9. Craig, S. W., and R. P. Johnson. Assembly of focal adhesions: progress, paradigms, and portents. Curr. Opin. Cell Biol. 8: 74-85, 1996.
10. c-src and is involved in neuronal differentiation. EMBO J. 12: 3789-3798, 1993.
11. Devary, Y., R. A. Gottlieb, T. Smeal, and M. Karin. The mammalian ultraviolet response is triggered by activation of src tyrosine kinases. Cell 71: 1081-1091, 1992.
12. Force, T., J. M. Kyriakis, J. Avruch, and J. V. Bonventre. Endothelin, vasopressin, and angiotensin II enhance tyrosine phosphorylation by protein kinase C-dependent and -independent pathways in glomerular mesangial cells. J. Biol. Chem. 266: 6650-6656, 1991.
13. Gordon, J. A. Use of vanadate as protein-phosphotyrosine phosphatase inhibitor. Methods Enzymol. 201: 477-482, 1991.
14. 2+. J. Gen. Physiol. 98: 791-813, 1991.
15. Horie, S., O. Moe, A. Tejedor, and R. J. Alpern. Preincubation in acid medium increases Na/H antiporter activity in cultured renal proximal tubule cells. Proc. Natl. Acad. Sci. USA 87: 4742-4745, 1990.
16. Huckle, W. R., C. A. Prokop, R. C. Dy, B. Herman, and S. Earp. Angiotensin II stimulates protein-tyrosine phosphorylation in a calcium-dependent manner. Mol. Cell Biol. 10: 6290-6298, 1990.
17. 1 renal epithelial cells. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F83-F88, 1992.
18. Kaiser, S., and N. P. Curthoys. Effect of pH and bicarbonate on phosphoenolpyruvate carboxykinase and glutaminase mRNA levels in cultured renal epithelial cells. J. Biol. Chem. 266: 9397-9402, 1991.
19. Kaiser, S., J. J. Hwang, H. Smith, C. Banner, T. C. Welbourne, and N. P. Curthoys. Effect of altered acid-base balance and of various agonists on levels of renal glutamate dehydrogenase mRNA. Am. J. Physiol. 262 (Renal Fluid Electrolyte Physiol. 31): F507-F512, 1992.
20. Krieger, N. S., N. E. Sessler, and D. A. Bushinsky. Acidosis inhibits osteoblastic and stimulates osteoclastic activity in vitro. Am. J. Physiol. 262 (Renal Fluid Electrolyte Physiol. 31): F442-F448, 1992.
21. Kypta, R. M., Y. Goldberg, E. T. Ulug, and S. A. Courtneidge. Association between the PDGF receptor and members of the src family of tyrosine kinases. Cell 62: 481-492, 1990.
22. Lattanzio, F. A., Jr. The effects of pH and temperature on fluorescent calcium indicators as determined with Chelex-100 and EDTA buffer systems. Biochem. Biophys. Res. Commun. 171: 102-108, 1990.
23. Levi, M., L. A. McDonald, P. A. Preisig, and R. J. Alpern. Chronic K depletion stimulates rat renal brush-border membrane Na-citrate cotransporter. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F767-F773, 1991.
24. Lotspeich, W. D. Renal hypertrophy in metabolic acidosis and its relation to ammonia excretion. Am. J. Physiol. 208: 1135-1142, 1965.
25. Lowe, C., T. Yoneda, B. F. Boyce, H. Chen, G. R. Mundy, and P. Soriano. Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts. Proc. Natl. Acad. Sci. USA 90: 4485-4489, 1993.
26. Moe, O. W., R. T. Miller, S. Horie, A. Cano, P.A. Preisig, and R. J. Alpern. Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts. J. Clin. Invest. 88: 1703-1708, 1991.
27. c-src. Nature Lond. 351: 69-72, 1991.
28. Okada, M., S. Nada, Y. Yamanashi, T. Yamamoto, and H. Nakagawa. CSK: a protein-tyrosine kinase involved in regulation of src family kinases. J. Biol. Chem. 266: 24249-24252, 1991.
29. Peng, Z.-Y., and C. A. Cartwright. Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association. Oncogene 11: 1955-1962, 1995.
30. Slotki, I., J. H. Schwartz, and E. A. Alexander. Interrelationship between cell pH and cell calcium in rat inner medullary collecting duct cells. Am. J. Physiol. 265 (Cell Physiol. 34): C432-C438, 1993.
31. Smith, J. B., S. D. Dwyer, and L. Smith. Lowering extracellular pH evokes inositol polyphosphate formation and calcium mobilization. J. Biol. Chem. 264: 8723-8728, 1989.
32. 3 cotransport in rat renal cortex. J. Clin. Invest. 86: 1076-1083, 1990.
33. Tamaoki, T. Use and specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors. Methods Enzymol. 201: 340-347, 1991.
34. Tannen, R. L. Relationship of renal ammonia production and potassium homeostasis. Kidney Int. 11: 453-465, 1977.
35. Teti, A., H. C. Blair, P. Schlesinger, M. Grano, A. Zambonin-Zallone, A. J. Kahn, S. L. Teitelbaum, and K. A. Hruska. Extracellular protons acidify osteoclasts, reduce cytosolic calcium, and promote expression of cell-matrix attachment structures. J. Clin. Invest. 84: 773-780, 1989.
36. Torres, V. E., D. K. Mujwid, D. M. Wilson, and K. H. Holley. Renal cystic disease and ammoniagenesis in Han:SPRD rats. J. Am. Soc. Nephrol. 5: 1193-1200, 1993.
37. Wakabayashi, S., P. Fafournoux, C. Sardet, and J. Pouyssegur. The Na/H antiporter cytoplasmic domain mediates growth factor signals and controls "H-sensing." Proc. Natl. Acad. Sci. USA 89: 2424-2428, 1992.
38. Yamaji, Y., M. Amemiya, A. Cano, P. A. Preisig, R. T. Miller, O. W. Moe, and R. J. Alpern. Overexpression of csk inhibits acid-induced activation of NHE-3. Proc. Natl. Acad. Sci. USA 92: 6274-6278, 1995.
39. Yamaji, Y., O. W. Moe, R. T. Miller, and R. J. Alpern. Acid activation of immediate early genes in renal epithelial cells. J. Clin. Invest. 94: 1297-1303, 1994.
40. Zhao, Y., M. Sudol, H. Hanafusa, and J. Krueger. Incresed tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation. Proc. Natl. Acad. Sci. USA 89: 8298-8302, 1992.
41. c-src by overexpression of a protein tyrosine phosphatase. Nature Lond. 359: 336-339, 1992.