Neural correlates of a spatial sensory-to-motor transformation in primary motor cortex

Journal of Neurophysiology

Volumn 77, Issue 3, 1997, Pages 1171-1194

  Shen, Liming ^a   Alexander, Garrett E ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARM MOVEMENT; ARTICLE; CONTROLLED STUDY; FEMALE; FORELIMB; MACACA; MOTOR CORTEX; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SENSORIMOTOR FUNCTION; TASK PERFORMANCE; TRAINING;

EID: 0030992196     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1997.77.3.1171     Document Type: Article

References (72)

1. ALEXANDER, G. E. AND CRUTCHER, M. D. Preparation for movement: neural representations of intended direction in three motor areas of the monkey. J Neurophysiol. 64: 133-150, 1990a.
2. ALEXANDER, G. E. AND CRUTCHER, M. D. Neural representations of the target (goal) of visually guided arm movements in three motor areas of the monkey. J Neurophysiol. 64: 164-178, 1990b.
3. ANDERSEN, R. A., BRACEWELL, R. M., BARASH, S., GNADT, J. W., AND FOGASSI, L. Eye position effects on visual, memory, and saccade-related activity in areas LIP and 7a of macaque. J. Neurosci. 10: 1176-1196, 1990.
4. BARBAS, H. AND PANDYA, D. N. Architecture and frontal cortical connections of the premotor cortex (area 6) in the rhesus monkey. J Comp. Neurol. 256: 211-228, 1987.
5. BAUSWEIN, E., FROMM, C., WERNER, W., AND ZIEMANN, U. Phasic and tonic responses of premotor and primary motor cortex neurons to torque changes. Exp. Brain Res. 86: 303-310, 1991.
6. BIBER, M. P., KNEISLEY, L. W., AND LA VAIL, J. H. Cortical neurons projecting to the cervical and lumbar enlargements of the spinal cord in young and adult rhesus monkeys. Exp. Neurol. 59: 492-508, 1978.
7. BOUSSAOUD, D. Primate premotor cortex: modulation of preparatory neuronal activity by gaze angle. J Neurophysiol. 73: 886-890, 1995.
8. BOUSSAOUD, D., BARTH, T. M., AND WISE, S. P. Effects of gaze on apparent visual responses of frontal cortex neurons. Exp. Brain Res. 93: 423-434, 1993.
9. BOUSSAOUD, D. AND WISE, S. P. Primate frontal cortex: neuronal activity following attentional versus intentional cues. Exp. Brain Res. 95: 1-27, 1993.
10. CAMINITI, R., JOHNSON, P. B., GALLI, C., FERRAINA, S., AND BURNOD, Y. Making arm movements within different parts of space: the premotor and motor cortical representation of a coordinate system for reaching to visual targets. J Neurosci. 11: 1182-1197, 1991.
11. CAMINITI, R., JOHNSON, P. B., AND URBANO, A. Making arm movements within different parts of space: dynamic aspects in the primate motor cortex. J Neurosci. 10: 2039-2058, 1990.
12. CAVADA, C. AND GOLDMAN-RAKIC, P. S. Posterior parietal cortex in rhesus monkey. II. Evidence for segregated corticocortical networks linking sensory and limbic areas with the frontal lobe. J Comp. Neurol. 287: 422-445, 1989.
13. CHAVIS, D. A. AND PANDYA, D. N. Further observations on corticofrontal connections in the rhesus monkey. Brain Res. 117: 369-386, 1976.
14. COLBY, C. L. AND DUHAMEL, J.-R. Heterogeneity of extrastriate visual areas and multiple parietal areas in the macaque monkey. Neuropsychotogia 29: 517-537, 1991.
15. CRUTCHER, M. D. AND ALEXANDER, G. E. Movement-related neuronal activity selectively coding either direction or muscle pattern in three motor areas of the monkey. J Neurophysiol. 64: 151-163, 1990.
16. DIPELLEGRiNO, G. AND WISE, S. P. Effects of attention on visuomotor activity in the premotor and prefrontal cortex of a primate. Somatosens. Mot. Res. 10: 245-262, 1993a.
17. DIPELLEGRINO, G. AND WISE, S. P. Visuospatial versus visuomotor activity in the premotor and prefrontal cortex of a primate. J Neurosci. 13: 1227-1243, 1993b.
18. DUM, R. P. AND STRICK, P. L. The origin of corticospinal projections from premotor areas in the frontal lobe. J Neurosci. 11: 667-689, 1991.
19. FU, Q.-G., FLAMENT, D., COLTZ, J. D., AND EBNER, T. J Temporal encoding of movement kinematics in the discharge of primary motor and premotor neurons. J Neurophysiol. 73: 836-854, 1995.
20. FU, Q.-G., SUAREZ, J. I., AND EBNER, T. J Neuronal specification of direction and distance during reaching movements in the superior precentral premotor area and primary motor cortex of monkeys. J Neurophysiol. 70: 2097-2116, 1993.
21. GEORGOPOULOS, A. P. Current issues in directional motor control. Trends Neurosci. 18: 506-510, 1995.
22. GEORGOPOULOS, A. P., ASHE, J., SMYRNIS, N., AND TAIRA, M. The motor cortex and the coding of force. Science Wash. DC 256: 1692-1695, 1992.
23. GEORGOPOULOS, A. P., KALASKA, J. F., AND CAMINITI, R. Relations between two-dimensional arm movements and single-cell discharge in motor cortex and area 5: movement direction versus movement end point. Exp. Brain Res. Suppl. 10: 175-183, 1985.
24. GEORGOPOULOS, A. P., KALASKA, J. F., CAMINTTI, R., AND MASSEY, J. T. On the relations between the direction of two-dimensional arm movements and cell discharge in primate motor cortex. J Neurosci. 2: 1527-1537, 1982.
25. GEORGOPOULOS, A. P., KALASKA, J. F., CRUTCHER, M. D., CAMINITI, R., AND MASSEY, J. T. The representation of movement direction in the motor cortex: single cell and population studies. In: Dynamic Aspects of Neocortical Function, edited by G. M. Edelman and W. M. Cowan. New York: Neurosciences Research Foundation, 1984, p. 501-524.
26. GEORGOPOULOS, A. P., KETTNER, R. E., AND SCHWARTZ, A. B. Primate motor cortex and free arm movements to visual targets in three-dimensional space. II. Coding of the direction of movement by a neuronal population. J Neurosci. 8: 2928-2937, 1988.
27. GEORGOPOULOS, A. P., LURITO, J, T., PETRIDES, M., SCHWARTZ, A. B., AND MASSEY, J. T. Mental rotation of the neuronal population vector. Science Wash. DC 243: 234-236, 1989.
28. GEORGOPOULOS, A. P., SCHWARTZ, A.B., AND KETTNER, R.E. Neuronal population coding of movement direction. Science Wash. DC 233: 1416-1419, 1986.
29. GEORGOPOULOS, A. P., TAIRA, M., AND LUKASHIN, A. Cognitive neurophysiology of the motor cortex. Science Wash. DC 260: 47-52, 1993.
30. HE, S.-Q., DUM, R. P., AND STRICK, P. S. Topographic organization of corticospinal projections from the frontal lobe: motor areas on the lateral surface of the hemisphere. J Neurosci. 13: 952-980, 1993.
31. HE, S.-Q., DUM, R. P., AND STRICK, P. S. Topographic organization of corticospinal projections from the frontal lobe: motor areas on the medial surface of the hemisphere. J Neurosci. 13: 3284-3306, 1995.
32. HOCHERMAN, S. AND WISE, S. P. Effects of hand movement path on motor cortical activity in awake, behaving rhesus monkeys. Exp. Brain Res. 83: 285-302, 1991.
33. JOHNSON, P. B., FERRAINA, S., BIANCHI, L., AND CAMINITI, R. Cortical networks for visual reaching: physiological and anatomical organization of frontal and parietal lobe arm regions. Cereb. Cortex 6: 102-119, 1996.
34. JUDGE, S. J., RICHMOND, B. J., AND CHU, F. C. Implantation of magnetic search coils for measurement of eye position: an improved method. Brain Res. 20: 535-538, 1980.
35. KALASKA, J. F., COHEN, D.A.D., HYDE, M. L., AND PRUD'HOMME, M. A comparison of movement direction-related versus load direction-related activity in primate motor cortex, using a two-dimensional reaching task. J Neurosci. 9: 2080-2102, 1989.
36. KALASKA, J. F. AND HYDE, M. L. Area 4 and 5: differences between the load direction-dependent variability of cells during active postural fixation. Exp. Brain Res. 59: 197-202, 1985.
37. KURATA, K. Corticocortical inputs to the dorsal and ventral aspects of the premotor cortex of macaque monkeys. Neurosci. Res. 12: 263-280, 1991.
38. KWAN, H. C., MACKAY, W. A., MURPHY, J. T., AND WONG, Y. C. Distribution of responses to visual cues for movement in precentral cortex of awake primates. Neurosci. Lett. 24: 123-128, 1981.
39. KWAN, H. C., MACKAY, W. A., MURPHY, J. T., AND WONG, Y. C. Properties of visual cue responses in primate precentral cortex. Brain Res. 343: 24-35, 1985.
40. LAMARRE, Y., BUSBY, L., AND SPIDALIERI, G. Fast ballistic arm movements triggered by visual, auditory and somesthetic stimuli in the monkey. I. Activity of precentral cortical neurons. J Neurophysiol. 50: 1343-1358, 1983.
41. LUPPINO, G., MATELLI, M., CAMARDA, R. M., GALLESE, V., AND RIZZOLATTI, G. Multiple representations of body movements in medial area 6 and adjacent cingulate cortex: an intracortical microstimulation study in macaque monkey. J Comp. Neurol. 311: 463-482, 1991.
42. LUPPINO, G., MATELLI, M., CAMARDA, R., AND RIZZOLATTI, G. Corticocortical connections of area F3 (SMA-proper) and area F6 (pre-SMA) in the macaque monkey. J. Comp. Neurol. 338: 114-140, 1993.
43. LURITO, J. T., GEORGAKOPOULOS, T., AND GEORGOPOULOS, A. P. Cognitive spatial-motor processes. 7. The making of movements at an angle from a stimulus direction: studies of motor cortical activity at the single cell and population levels. Exp. Brain Res. 87: 562-580, 1991.
44. MARTIN, J. H. AND GHEZ, C. Task-related coding of stimulus and response in cat motor cortex. Exp. Brain Res. 57: 427-442, 1985.
45. MATSUMURA, M. AND KUBOTA, K. Cortical projections to hand-arm motor area from postarcuate area in macaque monkeys: a histological study of retrograde transport of horseradish peroxidase. Neurosci. Lett. 11: 241-246, 1979.
46. MATSUZAKA, Y., AIZAWA, H., AND TANJI, J. A motor area rostral to the supplementary motor area (presupplementary motor area) in the monkey: neuronal activity during a learned motor task. J Neurophysiol. 68: 653-662, 1992.
47. MOUNTCASTLE, V. B., ANDERSEN, R. A., AND MOTTER, B. C. The influence of attentive fixation upon the excitability of the light-sensitive neurons of the posterior parietal cortex. J Neurosci. 1: 1218-1235, 1981.
48. MOUNTCASTLE, V. B., ATLURI, P. P., AND ROMO, R. Selective output-discriminative signals in the motor cortex of waking monkeys. Cereb. Cortex 2: 277-294, 1992.
49. MURRAY, E. A. AND COULTER, J. D. Organization of corticospinal neurons in the monkey. J Comp. Neurol. 195: 339-365, 1981.
50. MUSHIAKE, H., INASE, M., AND TANJI, J. Neuronal activity in the primate premotor, supplementary, and precentral motor cortex during visually guided and internally determined sequential movements. J Neurophysiol. 66: 705-718, 1991.
51. PETRIDES, M. AND PANDYA, D. N. Projections to the frontal cortex from the posterior parietal region in the rhesus monkey. J Comp. Neurol. 228: 105-116, 1984.
52. RIEHLE, A. Visually induced signal-locked neuronal activity changes in precentral motor areas of the monkey: hierarchical progression of signal processing. Brain Res. 540: 131-137, 1991.
53. RIEHLE, A., KORNBLUM, S., AND REQUIN, J. Neuronal coding of stimulus-response association rules in the motor cortex. Neuroreport 5: 2462-2464, 1994a.
54. RIEHLE, A., MACKAY, W. A., AND REQUIN, J. Are extent and force independent movement parameters? Preparation- and movement-related neuronal activity in the monkey cortex. Exp. Brain Res. 99: 56-74, 1994b.
55. RIEHLE, A. AND REQUIN, J. Monkey primary motor and premotor cortex: single-cell activity related to prior information about direction and extent of an intended movement. J Neurophysiol. 61: 534-549, 1989.
56. RIEHLE, A. AND REQUIN, J. Neuronal correlates of the specification of movement direction and force in four cortical areas of the monkey. Behav. Brain Res. 70: 1-13, 1995.
57. ROBINSON, D. A. A method of measuring eye movement using a scleral search coil in a magnetic field. IEEE Trans. Biomed. Electron. 10: 137-145, 1963.
58. SALTZMAN, E. Levels of sensorimotor representation. J Math. Psychol. 20: 91-163, 1979.
59. SCHWARTZ, A. B., KETTNER, R. E., AND GEORGOPOULOS, A. P. Primate motor cortex and free arm movements to visual targets in three-dimensional space. I. Relations between single cell discharge and direction of movement. J Neurosci. 8: 2913-2927, 1988.
60. SCOTT, S. H. AND KALASKA, J. F. Motor cortical activity is altered by changes in arm posture for identical hand trajectories. J Neurophysiol. 73: 2563-2567, 1995.
61. SCOTT, S. H. AND KALASKA, J. F. Reaching movements with similar hand paths but different arm orientations. I. Activity of individual cells in motor cortex. J Neurophysiol. 77: 826-852, 1997.
62. SHEN, L. AND ALEXANDER, G. E. Primate motor cortex: neuronal activity coding for operations in external space that are independent of limb trajectory. Soc. Neurosci. Abstr. 20: 981, 1994.
63. SHEN, L. AND ALEXANDER, G. E. Preferential representation of instructed target location versus limb trajectory in dorsal premotor area. J Neurophysiol. 77: 1195-1212, 1997.
64. SNEDECOR, G. W. AND COCHRAN, W. G. Statistical Methods. Ames, IA: Iowa State Univ. Press, 1989.
65. STEINMETZ, M. A., CONNOR, C. E., CONSTANTINIDIS, C., AND MCLAUGHLIN, J. R. Covert attention suppresses neuronal responses in area 7a of the posterior parietal cortex. J. Neurophysiol. 72: 1020-1023, 1994.
66. STEINMETZ, M. A. AND CONSTANTINTDIS, C. Neurophysiological evidence for a role of posterior parietal cortex in redirected visual attention. Cereb. Cortex 5: 448-456, 1995.
67. THACH, W. T. Correlation of neural discharge with pattern and force of muscular activity, joint position, and direction of intended next movement in motor cortex and cerebellum. J Neurophysiol. 41: 654-676, 1978.
68. TOKUNO, H. AND TANJI, J. Input organization of distal and proximal forelimb areas in the monkey primary motor cortex: a retrograde double labeling study. J Comp. Neurol. 333: 199-209, 1993.
69. VOGT, B. A. AND PANDYA, D. N. Cingulate cortex of the rhesus monkey. II. Cortical afferents. J Comp. Neurol. 262: 271-289, 1987.
70. WANNIER, T. M. W., MAIER, M. A., AND HEPP-REYMOND, M.-C. Responses of motor cortex neurons to visual stimulation in the alert monkey. Neurosci. Lett. 98: 63-68, 1989.
71. WEINRICH, M. AND WISE, S. P. The premotor cortex of the monkey. J Neurosci. 2: 1329-1345, 1982.
72. WERNER, W., BAUSWEIN, E., AND FROMM, C. Static firing rates of premotor and primary motor cortical neurons associated with torque and joint position. Exp. Brain Res. 86: 293-302, 1991.