Effects of α1-adrenoceptor and Ca2+ channel inhibition on norepinephrine-induced thermoregulatory behavior in the cold

Pharmacology Biochemistry and Behavior

Volumn 57, Issue 1-2, 1997, Pages 185-189

  Carlisle, Harry J ^a   Stock, Michael J ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Behavior; Nifedipine; Norepinephrine; Rat; Temperature regulation; WB 4101

Indexed keywords

2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; NIFEDIPINE; NORADRENALIN BITARTRATE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; COLD EXPOSURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; FEMALE; INSTRUMENTAL CONDITIONING; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; TEMPERATURE MEASUREMENT; THERMOREGULATION;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; BODY TEMPERATURE REGULATION; CALCIUM CHANNEL BLOCKERS; COLD; CONDITIONING, OPERANT; DIOXANES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; NIFEDIPINE; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030992094     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(96)00307-3     Document Type: Article

References (26)

1. Bray, G. A.; Fisler, J.; York, D. A. Neuroendocrine control of the development of obesity: Understanding gained from studies of experimental animal models. In Frontiers in Neuroendocrinology, Vol. 57, No. 2. New York: Raven Press, 1990:pp. 128-181.
2. Carlisle, H. J. Heat intake and hypothalamic temperature during behavioral temperature regulation. J. Comp. Physiol. Psychol. 61: 388-397;1966.
3. Carlisle, H. J.; Dubuc, P. U.; Stock, M. J. Effects of epinephrine on thermoregulatory behavior in lean and obese Zucker rats in the cold. Pharmacol. Biochem. Behav. 51:255-261;1995.
4. 3) adrenergic agonists on thermoregulatory behavior. Pharmacol. Biochem. Behav. 40:249-254;1991.
5. Carlisle, H. J.; Stock, M. J. Potentiation of thermoregulatory responses to isoproterenol by β-adrenergic antagonists. Am. J. Physiol. 263:R915-R923;1992.
6. Carlisle, H. J.; Stock, M. J. Effect of cold ambient temperatures on metabolic responses to β-adrenergic agonists. Exp. Physiol. 78:775-786;1993.
7. Carlisle, H. J.; Stock, M. J. Thermoregulatory effects of beta adrenoceptors: Effects of selective agonists and the interaction of antagonists with isoproterenol and BRL-35135 in the cold. J. Pharmacol. Exp. Ther. 266:1446-1453;1993.
8. Carlisle, H. J.; Stock, M. J. Temperature-dependent effects of α-adrenergic agonists and antagonists in the cold. Pharm. Biochem. Behav. 51:263-270;1995.
9. 2-adrenoceptors as cutaneous thermosensors. News in Physiol. Sci. 6:251-255;1991.
10. Flavahan, N. A.; Vanhoutte, P. M. Effect of cooling on alpha-1 and alpha-2 adrenergic responses in canine saphenous and femoral veins. J. Pharmacol. Exp. Ther. 238:139-147;1986.
11. Gagalo, I. T.; Hac, E. E.; Szreder, Z. A comparative study of the effect of verapamil and prazosin on the thermoregulatory responses induced by cold or exogenous noradrenaline. Gen. Pharmacol. 23:475-479;1992.
12. Granger, D. N.; Richardson, P. D. I.; Kvietys, P. R.; Mortillaro, N. A. Intestinal blood flow. Gastroenterology 78:837-863;1980.
13. Himms-Hagen, J. Brown adipose tissue thermogenesis: role in thermoregulation, energy regulation and obesity. In: Schonbaum, E.; Lomax, P., eds. Thermoregulation - Physiology and Biochemistry. New York: Pergamon Press;1990:327-414.
14. Kent, S.; Satinoff, E. Influence of ambient temperature on sleep and body temperature after phentolamine in rats. Brain Res. 511:227-233;1990.
15. Kent, S.; Hurd, M.; Satinoff, E. Phentolamine and thermoregulation in rats. Pharmacol. Biochem. Behav. 40:709-716;1991.
16. Lin, M. T.; Chandra, A.; Fung, T. C. Effects of phentolamine on thermoregulatory functions of rats to different ambient temperatures. Can. J. Physiol. Pharmacol. 57:1401-1406;1979.
17. Nichols, A. J.; Hiley, C. R. Identification of adrenoceptors and dopamine receptors mediating vascular responses in the superior mesenteric arterial bed of the rat. J. Pharm. Pharmacol. 37: 110-115; 1985.
18. Refinetti, R.; Menaker, M. The circadian rhythm of body temperature. Physiol. Behav. 51:613-637;1992.
19. Ruffulo, R. R.; Nichols, A. J.; Stadel, J. M; Hieble, J. P Structure and function of α-adrenoceptors. Pharmacol. Revs. 43:475-505;1991.
20. Szreder, Z. Comparison of the effect of prazosin with that of dihydrobenzperidol and nifedipine on thermoregulatory responses produced by pyrogen in rabbits. Gen. Pharmacol. 21: 833-838;1990.
21. Szreder, Z. Do central mechanisms participate in the thermoregulatory activity of prazosin? Gen. Pharmacol. 23:1121-1124;1992.
22. Szreder, Z. Antipyresis as a result of alpha-1 adrenoceptor blockade. Gen. Pharmacol. 24:455-460;1993a.
23. 2adrenoceptors in normothermic and febrile rabbits. Gen. Pharmacol. 24:929-941;1993b.
24. Szreder, Z.; Gagalo, I. A comparative study on the thermoregulatory effects of prazosin, dihydrobenzperidol and nifedipin on 2,4-dinitrophenol induced hyperthermia in rabbits. Gen. Pharmacol. 22:1139-1142;1991.
25. Zylan, K. D.; Carlisle, H. J. Paradoxical effects of exogenous norepinephrine on cold-induced thermogenesis in the rat. Pharmacol. Biochem. Behav. 39:21-24;1991.
26. Zylan, K. D.; Carlisle, H. J. Effect of ambient temperature on paradoxical responses to norepinephrine. Pharmacol. Biochem. Behav. 43:577-582, 1992.