Serum aminotransferase levels and histological disease in chronic hepatitis C

Acta Gastro-Enterologica Belgica

Volumn 60, Issue 1, 1997, Pages 11-14

  Michielsen, P P ^a,c   Hauben, E I ^a   Ramon, A M ^a,b   Van Marck, E A ^a   Pelckmans, P A ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b Intl Institute of Immunopathology   (Germany)

^c ANTWERP UNIVERSITY HOSPITAL   (Belgium)

Author keywords

alanine aminotransferase; aspartate aminotransferase; chronic hepatitis C; grading; liver histology; staging

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; INTERFERON; VIRUS RNA;

ADULT; AGED; ARTICLE; DISEASE SEVERITY; FEMALE; HEPATITIS C; HISTOLOGY; HUMAN; LIVER BIOPSY; MAJOR CLINICAL STUDY; MALE;

ADULT; AGED; AGED, 80 AND OVER; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BIOPSY; FEMALE; HEPATITIS C; HEPATITIS, CHRONIC; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC;

EID: 0030991461     PISSN: 00015644     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. DE GROOTE J., DESMET V.J., GEDIGK P., KORB G., POULSEN H., SCHEUER P.J., SCHMID M , THALER H., UEHLINGER E A classification of chronic hepatitis. Lancet, 1968, 2 : 626-628.
2. LUDWIG J. Histopathological diagnosis and terminology of chronic hepatitis. J. Hepatol , 1995, 23 (Suppl. 1) : 49-53.
3. DESMET V.J., GERBER M., HOOFNAGLE J.H., MANNS M., SCHEUER P.J. Classification of chronic hepatitis . diagnosis, grading and staging. Hepatology, 1994, 19: 1513-1520.
4. International Working Party. Terminology of chronic hepatitis. Am J. Gastroenterol., 1995, 90 : 181 -189
5. KNODELL R.G., ISHAK K.G., BLACK W.C., CHEN T.S., CRAIG R.G., KAPLOWITZ N., KIERNAN T.W., WOLLMAN J. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology, 1981, 1 , 431-435.
6. BlANCHI L., GUDAT F. Chronic hepatitis. In MACSWEEN R N.M., ANTHONY P P., SCHEUER P.J., BURT A.D., PORTMANN B C. (eds). Pathology of the Liver. Churchill Livingstone, Edinburgh, 1994 349-395.
7. ESTEBAN J.I , LÓPEZ-TALAVERA J.C., GENESCÀ J., MADOZ P., VILADOMIU L., MUÑIZ E., MARTIN-VEGA C., ROSELL M., ALLFNDE H., VIDAL X, GONZÁLEZ J.M., ESTEBAN R., GUARDIA J. High rate of infectivity and liver disease in blood donors with antibodies to hepatitis C virus. Ann. Intern. Med., 1991, 115 : 443-449
8. BROUWER J.T., NEVENS F., KLETER G.E.M., ELEWAUT A., ADLER M., BRENARD R., CHAMULEAU R.A.F.M., MICHIELSEN P., PIROTTE J., HAUTEKEETE M., ARENDT V., FEVERY J , SCHALM S.W. Efficacy of Interferon dose and factors predictive of sustained response in chronic hepatitis C . final results of a Benelux multicentre study in 350 patients. J. Hepatol., 1995, 23 (Suppl. 1) : 85 (Abstract)
9. GORDON S.C., KODALI V.P., SILVERMAN A.L., DMUCHOWSKI C.F., URDEA M.S., CHAN C.S., WILBER J.C Levels of hepatitis C virus RNA and liver histology in chronic type C hepatitis. Am. J. Gastroenterol., 1994, 89 : 1458- 1461.
10. YUKI N., HAYASHI N., TAKEHARA T., HAGIWARA H., HIRAMATSU N., NAITO M., KAWANISHI Y , KATAYAMA K., KASAHARA A., FUSAMOTO H., KAMADA T Serum hepatitis C virus RNA levels and liver injury in volunteer blood donors. Am. J. Gastroenterol., 1994, 89 : 1462-1466.
11. PEPSICO M., ROMANO M. Alanine aminotransferase measurements and histological disease in hepatitis C. Lancet, 1993, 342 : 1369-1370 (Letter).
12. CAHEN D L., VAN LEEUWEN D.J., TEN KATE F.J.W., BLOK A.P R., OUSTING J., CHAMULEAU R.A.F.M. Do serum ALAT values reflect the inflammatory activity in the liver of patients with chronic viral hepatitis ? Liver, 1996, 16 : 105-109.
13. McINTYRE N., ROSALKI S. Biochemical investigations in the management of liver disease. In Oxford Textbook of Clinical Hepatology, Oxford University Press, Oxford, 1991 : 293-309.
14. DI BISCEGLIE A.M. MARTIN P., KASSIANIDES C , LISKERMELMAN M., MURRAY L., WAGGONER J., GOODMAN, Z., BANKS S M., HOOFNAGLE J.H. Recombinant interferon alfa theraphy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. N. Engl. J. Med., 1989, 321 . 1506-1510.
15. Benelux Multicentre Trial Study Group. Benelux multicentre trial of alpha interferon treatment for chronic hepatitis C : standard v high dose treatment monitored by biochemical and virological markers (interim analysis). Gut, 1993, 34 (Suppl.) : S119-S120.
16. VAN THIEL D.H., CARACENI P., MOLLOY P.J., HASSANEIN T , KANIA R.J., GURAKAR A , FRIEDLANDER L. Chronic hepatitis C in patients with normal or near normal alaninc aminotransferase levels : the role of interferon α2b therapy. J. Hepatol., 1995, 23 : 503-508.