Synthesis and transporter binding properties of 2,3-diphenyltropane stereoisomers. Comparison to 3β-phenyltropane-2β-carboxylic acid esters

Journal of Medicinal Chemistry

Volumn 40, Issue 8, 1997, Pages 1247-1251

  Chang, An Chih ^a   Burgess, Jason P ^a   Mascarella, S Wayne ^a   Abraham, Philip ^a   Kuhar, Michael J ^b   Carroll, F Ivy ^a  

^a RTI INTERNATIONAL   (United States)

^b NIDA Addiction Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2ALPHA,3ALPHA DIPHENYLTROPANE; 2BETA,3BETA DIPHENYLTROPANE; ALPHA ADRENERGIC RECEPTOR; COCAINE; DOPAMINE TRANSPORTER; SEROTONIN RECEPTOR; TROPARIL; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG CONFORMATION; DRUG SELECTIVITY; DRUG SYNTHESIS; DRUG TRANSPORT; HYDROPHOBICITY; RACEMIC MIXTURE; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

BINDING, COMPETITIVE; CARRIER PROTEINS; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS;

EID: 0030991135     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960703k     Document Type: Article

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