Methamphetamine-induced decrease in tryptophan hydroxylase activity: Role of 5-hydroxytryptaminergic transporters

European Journal of Pharmacology

Volumn 324, Issue 2-3, 1997, Pages 179-186

  Fleckenstein, Annette E ^a   Beyeler, Meisha L ^a   Jackson, Jonathan C ^a   Wilkins, Diana G ^a   Gibb, James W ^a   Hanson, Glen R ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

5 HT (5 hydroxytryptamine, serotonin); Dopamine transport; Fluoxetine; Hyperthermia; Methamphetamine

Indexed keywords

CHLORAMPHETAMINE; CITALOPRAM; DOPAMINE; FLUOXETINE; METHAMPHETAMINE; PARGYLINE; TRYPTOPHAN HYDROXYLASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; DOPAMINE UPTAKE; ENZYME ACTIVITY; IN VITRO STUDY; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONINERGIC SYSTEM;

ANIMALS; CARRIER PROTEINS; CENTRAL NERVOUS SYSTEM STIMULANTS; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; FLUOXETINE; HIPPOCAMPUS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; METHAMPHETAMINE; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TRYPTOPHAN HYDROXYLASE; VISUAL CORTEX;

EID: 0030991076     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)00081-2     Document Type: Article

References (35)

1. Albers, D.S. and P.K. Sonsalla, 1995, Methamphetamine-induced hyperthermia and dopaminergic neurotoxicity in mice: pharmacological profile of protective and nonprotective agents, J. Pharmacol. Exp. Ther. 275, 1104.
2. Axt, K.J. and M.E. Molliver, 1991, Immunocytochemical evidence for methamphetamine-induced serotonergic axon loss in the rat brain, Synapse 9, 302.
3. 3H]Desipramine binding to rat brain tissue: binding to both noradrenaline uptake sites and sites not related to noradrenaline neurons, J. Neurochem. 52, 1099.
4. Bakhit, C. and J.W. Gibb, 1981, Methamphetamine-induced depression of tryptophan hydroxylase: Recovery following acute treatment, Eur. J. Pharmacol. 76, 229.
5. Bakhit, C., M.E. Morgan, M.A. Peat and J.W. Gibb, 1981, Long-term effects of methamphetamine on the synthesis and metabolism of 5-hydroxytryptamine in various regions of the rat brain, Neuropharmacology 20, 1135.
6. Berger, B. and J. Glowinski, 1978, Dopamine uptake into serotoninergic terminals in vitro: a valuable tool for the histochemical differentiation of catecholaminergic and serotoninergic terminals in rat cerebral structures, Brain Res. 147, 29.
7. Boja, J.W., R. McNeill, A. Lewin, P. Abraham, F.I. Carroll and M.J. Kuhar, 1992, Selective dopamine transport inhibition by cocaine analogs, Neuroreport 3, 984.
8. Bowyer, J.F., A.W. Tank, G.D. Newport, W. Slikker Jr., S.F. Ali and R.R. Holson, 1992, The influence of environmental temperature on the transient effects of methamphetamine on dopamine levels and dopamine release in rat striatum, J. Pharmacol. Exp. Ther. 260, 817.
9. Bowyer, J.F., D.L. Davies, L. Schmued, H.W. Broening, G.D. Newport, G.D., W. Slikker and R.R. Holson, 1994, Further studies of hyperthermia in methamphetamine neurotoxicity. J. Pharmacol. Exp. Ther. 268, 1571.
10. Brownstein, D.M. and J.-S. Hong, 1995, Effects of sulpiride and SCH23390 on methamphetamine-induced changes in body temperature and lethality, J. Pharmacol. Exp. Ther. 274, 943.
11. De Souza, E.B. and B.L. Kuyatt, 1987, Autoradiographic localization of H-paroxetine-labeled serotonin uptake sites in rat brain, Synapse 1, 488.
12. Farfel, G.M. and L.S. Seiden, 1995, Role of hypothermia in the mechanism of protection against serotonergic toxicity. II. Experiments with methamphetamine, p-chloroamphetamine, fenfluramine, dizocilpine and dextromethorphan, J. Pharmacol. Exp. Ther. 272, 868.
13. th Annual Meeting, Society for Neuroscience, Abstract 815.7.
14. Gibb, J.W., G.R. Hanson and M. Johnson, 1994, Neurochemical mechanisms of toxicity, in: Amphetamine and its Analogs, eds. A.K. Cho and D.S. Segal (Academic Press, New York, NY) p. 269.
15. Giovanni, A., L.P. Liang, T.G. Hastings and M.J. Zigmond, 1995, Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine, J. Neurochem. 64, 1819.
16. Habert, E., D. Graham and S.Z. Langer, 1986, Solubilization and characterization of the 5-hydroxytryptamine transporter complex from rat cerebral cortical membranes, Eur. J. Pharmacol. 122, 197.
17. Hotchkiss, A.J. and J.W. Gibb, 1980, Long-term effects of multiple doses of methamphetamine on tryptophan hydroxylase and tyrosine hydroxylase activity in rat brain, J. Pharmacol. Exp. Ther. 214, 257.
18. Hyttel, J., 1982, Citalopram - pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity, Prog. Neuropsychopharmacol. Biol. Psychiat. 6, 277.
19. Johnson, M., I. Elayan, G.R. Hanson, R.L. Foltz, J.W. Gibb and H.K. Lim, 1992, Effects of 3,4-dihydroxymethamphetamine and 2,4,5-trihydroxymethamphetamine, two metabolites of 3,4-methylenedioxymethamphetamine, on central serotonergic and dopaminergic systems, J. Pharmacol. Exp. Ther. 261, 447.
20. Johnson, M., D.M. Stone, G.R. Hanson and J.W. Gibb, 1987, Role of the dopaminergic nigrostriatal pathway in methamphetamine-induced depression of the neostriatal serotonergic system, Eur. J. Pharmacol. 135, 231.
21. McPherson, G.A., 1986, EBDA-LIGAND-KINETIC-LOWRY, Elsevier-BIOSOFT, Cambridge, UK.
22. Ricaurte, G.A., R.W. Fuller, K.W. Perry, L.S. Seiden and C.R. Schuster, 1983, Fluoxetine increases long-lasting neostriatal dopamine depletion after administration of d-methamphetamine and d-amphetamine, Neuropharmacology 22, 1165.
23. Ricaurte, G.A., C.R. Schuster and L.S. Seiden, 1980, Long-term effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: a regional study, Brain Res. 193, 153.
24. Sanders-Bush, E., J.A. Bushing and F. Sulser, 1975, Long-term effects of p-chloroamphetamine and related drugs on central serotonergic mechanisms, J. Pharmacol. Exp. Ther. 192, 33.
25. Schmidt, C.J. and J.W. Gibb, 1985, Role of the serotonin uptake carrier in the neurochemical response to methamphetamine: effects of citalopram and chlorimipramine, Neurochem. Res. 10, 637.
26. Schmidt, C.J. and W. Lovenberg, 1985, In vitro demonstration of dopamine uptake by neostriatal serotonergic neurons of the rat, Neurosci. Lett. 59, 9.
27. Schmidt, C.J., J.K. Ritter, P.K. Sonsalla, G.R. Hanson and J.W. Gibb, 1985, Role of dopamine in the neurotoxic effects of methamphetamine, J. Pharmacol. Exp. Ther. 233, 539.
28. Sette, M., M.S. Briley and S.Z. Langer, 1983, Complex inhibition of H-imipramine binding by serotonin and nontricyclic serotonin uptake blockers, J. Neurochem. 40, 622.
29. 3-dopamine uptake into rat brain homogenates, J. Pharmacol. Exp. Ther. 165, 78.
30. 2 dopamine receptor subtypes in mediating the methamphetamine-induced changes in monoamine systems, J. Pharmacol. Exp. Ther. 238, 932.
31. Sprague, J.E. and D.E. Nichols, 1995, The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits, J. Pharmacol. Exp. Ther. 273, 667.
32. Stone, D.M., M. Johnson, G.R. Hanson and J.W. Gibb, 1989, Acute inactivation of tryptophan hydroxylase by amphetamine analogs involves the oxidation of sulfhydryl sites, Eur. J. Pharmacol. 172, 93.
33. 3H]Nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding, J. Pharmacol. Exp. Ther. 260, 427.
34. Wong, D.T., J.S. Horng, F.P. Bymaster, K.L. Hauser and B.B. Molloy, 1974, A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine, Life Sci. 15, 471.
35. Woolverton, W.L., G.A. Ricaurte, L.S. Forno and L.S. Seiden, 1989, Long-term effects of chronic methamphetamine administration in rhesus monkeys, Brain Res. 486, 73.