메뉴 건너뛰기




Volumn 40, Issue 3, 1997, Pages 397-409

Biologic agents for treating rheumatoid arthritis: Concepts and progress

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD5 ANTIGEN; CD7 ANTIGEN; CELL SURFACE MARKER; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 6; MONOCLONAL ANTIBODY; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; T LYMPHOCYTE RECEPTOR; TISSUE INHIBITOR OF METALLOPROTEINASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030991059     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.1780400302     Document Type: Review
Times cited : (128)

References (123)
  • 1
    • 0027408042 scopus 로고
    • Do nonimmunologically mediated pathways play a role in the pathogenesis of rheumatoid arthritis?
    • Koopman WJ, Gay S: Do nonimmunologically mediated pathways play a role in the pathogenesis of rheumatoid arthritis? Rheum Dis Clin North Am 19:107-122, 1993
    • (1993) Rheum Dis Clin North Am , vol.19 , pp. 107-122
    • Koopman, W.J.1    Gay, S.2
  • 2
    • 0023278475 scopus 로고
    • Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4
    • Wofsy D, Seaman WE: Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4. J Immunol 138:3247-3253, 1987
    • (1987) J Immunol , vol.138 , pp. 3247-3253
    • Wofsy, D.1    Seaman, W.E.2
  • 7
    • 0030063898 scopus 로고    scopus 로고
    • Percentage of anti-CD4 monoclonal antibody-coated lymphocytes in the rheumatoid joint is associated with clinical improvement: Implications for the development of immunotherapeutic dosing regimens
    • Choy EHS, Pitzalis C, Cauli A, Bijl JA, Schantz A, Woody J, Kingsley GH, Panyi GS: Percentage of anti-CD4 monoclonal antibody-coated lymphocytes in the rheumatoid joint is associated with clinical improvement: Implications for the development of immunotherapeutic dosing regimens. Arthritis Rheum 39:52-56, 1996
    • (1996) Arthritis Rheum , vol.39 , pp. 52-56
    • Choy, E.H.S.1    Pitzalis, C.2    Cauli, A.3    Bijl, J.A.4    Schantz, A.5    Woody, J.6    Kingsley, G.H.7    Panyi, G.S.8
  • 9
    • 0029115051 scopus 로고
    • A randomized, double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis
    • Van der Lubbe PA, Dijkmans BAC, Markusse HM, Nässander U, Breedveld FC: A randomized, double-blind, placebo-controlled study of CD4 monoclonal antibody therapy in early rheumatoid arthritis. Arthritis Rheum 38:1097-1106, 1995
    • (1995) Arthritis Rheum , vol.38 , pp. 1097-1106
    • Van der Lubbe, P.A.1    Dijkmans, B.A.C.2    Markusse, H.M.3    Nässander, U.4    Breedveld, F.C.5
  • 10
    • 0028238428 scopus 로고
    • Treatment of refractory rheumatoid arthritis with a chimeric anti-CD4 monoclonal antibody: Long-term followup of CD4+ T cell counts
    • Moreland LW, Pratt PW, Bucy RP, Jackson BS, Feldman JW, Koopman WJ: Treatment of refractory rheumatoid arthritis with a chimeric anti-CD4 monoclonal antibody: long-term followup of CD4+ T cell counts. Arthritis Rheum 37:834-838, 1994
    • (1994) Arthritis Rheum , vol.37 , pp. 834-838
    • Moreland, L.W.1    Pratt, P.W.2    Bucy, R.P.3    Jackson, B.S.4    Feldman, J.W.5    Koopman, W.J.6
  • 12
    • 0023839324 scopus 로고
    • Induction of immune tolerance during administration of monoclonal antibody to L3T4 does not depend on depletion of L3T4+ cells
    • Carteron NL, Wofsy D, Seaman WE: Induction of immune tolerance during administration of monoclonal antibody to L3T4 does not depend on depletion of L3T4+ cells. J Immunol 140:713-716, 1988
    • (1988) J Immunol , vol.140 , pp. 713-716
    • Carteron, N.L.1    Wofsy, D.2    Seaman, W.E.3
  • 14
    • 0000056486 scopus 로고    scopus 로고
    • T cell hypothesis in rheumatoid arthritis tested by humanized non-depleting anti-CD4 monoclonal antibody treatment I: Suppression of disease activity and acute phase response
    • Panayi GS, Choy EHS, Connolly DJA, Regan T, Manna VK, Rapson N, Kingsley GH, Johnston JM: T cell hypothesis in rheumatoid arthritis tested by humanized non-depleting anti-CD4 monoclonal antibody treatment I: suppression of disease activity and acute phase response (abstract). Arthritis Rheum 39 (suppl 9):S244, 1996
    • (1996) Arthritis Rheum , vol.39 , Issue.SUPPL. 9
    • Panayi, G.S.1    Choy, E.H.S.2    Connolly, D.J.A.3    Regan, T.4    Manna, V.K.5    Rapson, N.6    Kingsley, G.H.7    Johnston, J.M.8
  • 15
    • 0008585117 scopus 로고
    • Clinical activity in an early phase I trial of Primatized™ IDEC-CE9.1 - An anti-CD4 monoclonal antibody - in RA
    • Solinger AM, Yocum DE, Tesser J, Gluck O, O'Sullivan F, Henkel C, Cornell M, Lipani J: Clinical activity in an early phase I trial of Primatized™ IDEC-CE9.1 - an anti-CD4 monoclonal antibody - in RA (abstract). Arthritis Rheum 37 (suppl 9):S337, 1994
    • (1994) Arthritis Rheum , vol.37 , Issue.SUPPL. 9
    • Solinger, A.M.1    Yocum, D.E.2    Tesser, J.3    Gluck, O.4    O'Sullivan, F.5    Henkel, C.6    Cornell, M.7    Lipani, J.8
  • 24
    • 0024512227 scopus 로고
    • Beneficial effects of monoclonal antibody to interleukin-2 receptor on activated T-cells in rheumatoid arthritis
    • Kyle V, Coughlan RJ, Tighe H, Waldmann H, Hazleman BL: Beneficial effects of monoclonal antibody to interleukin-2 receptor on activated T-cells in rheumatoid arthritis. Ann Rheum Dis 48:428-429, 1989
    • (1989) Ann Rheum Dis , vol.48 , pp. 428-429
    • Kyle, V.1    Coughlan, R.J.2    Tighe, H.3    Waldmann, H.4    Hazleman, B.L.5
  • 28
    • 0023900553 scopus 로고
    • Possible role of Vβ T cell receptor genes in susceptibility to collagen-induced arthritis in mice
    • Banerjee S, Haqqi TM, Luthra HS, Stuart JM, David CS: Possible role of Vβ T cell receptor genes in susceptibility to collagen-induced arthritis in mice. J Exp Med 167:532-539, 1988
    • (1988) J Exp Med , vol.167 , pp. 532-539
    • Banerjee, S.1    Haqqi, T.M.2    Luthra, H.S.3    Stuart, J.M.4    David, C.S.5
  • 29
    • 0025360562 scopus 로고
    • Clinical modeling of T-cell vaccination against autoimmune disease in rats: Selection of antigen-specific T-cells using a mitogen
    • Mor F, Lohse AW, Karin N, Cohen IR: Clinical modeling of T-cell vaccination against autoimmune disease in rats: selection of antigen-specific T-cells using a mitogen. J Clin Invest 85:1594-1598, 1990
    • (1990) J Clin Invest , vol.85 , pp. 1594-1598
    • Mor, F.1    Lohse, A.W.2    Karin, N.3    Cohen, I.R.4
  • 30
    • 0028973013 scopus 로고
    • Vaccination with a recombinant Vα domain of a TCR prevent the development of collagen-induced arthritis
    • Rosloniec EF, Brand DD, Whittington KB, Stuart JM, Ciubotaru M, Ward ES: Vaccination with a recombinant Vα domain of a TCR prevent the development of collagen-induced arthritis. J Immunol 155:4504-4511, 1995
    • (1995) J Immunol , vol.155 , pp. 4504-4511
    • Rosloniec, E.F.1    Brand, D.D.2    Whittington, K.B.3    Stuart, J.M.4    Ciubotaru, M.5    Ward, E.S.6
  • 31
    • 0029886958 scopus 로고    scopus 로고
    • Immunization with T-cell receptor Vβ chain peptides deletes pathogenic T-cells and prevents the induction of collagen-induced arthritis in mice
    • Haqqi TM, Qu X-M, Anthony D, Ma J, Sy MS: Immunization with T-cell receptor Vβ chain peptides deletes pathogenic T-cells and prevents the induction of collagen-induced arthritis in mice. J Clin Invest 987:2849-2858, 1996
    • (1996) J Clin Invest , vol.987 , pp. 2849-2858
    • Haqqi, T.M.1    Qu, X.-M.2    Anthony, D.3    Ma, J.4    Sy, M.S.5
  • 32
    • 0028172613 scopus 로고
    • Increased frequency of Vβ17-positive T cells in patients with rheumatoid arthritis
    • Zagon G, Tumang JR, Li Y, Friedman SM, Crow MK: Increased frequency of Vβ17-positive T cells in patients with rheumatoid arthritis. Arthritis Rheum 37:1431-1440, 1994
    • (1994) Arthritis Rheum , vol.37 , pp. 1431-1440
    • Zagon, G.1    Tumang, J.R.2    Li, Y.3    Friedman, S.M.4    Crow, M.K.5
  • 34
    • 0025840491 scopus 로고
    • Limited T-cell receptor B-chain heterogenity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis
    • Howell MD, Diveley JP, Lundeen KA, Esty A, Winters ST, Carlo DJ, Brostoff SW: Limited T-cell receptor B-chain heterogenity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis. Proc Natl Acad Sci U S A 88:10921-10925, 1991
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 10921-10925
    • Howell, M.D.1    Diveley, J.P.2    Lundeen, K.A.3    Esty, A.4    Winters, S.T.5    Carlo, D.J.6    Brostoff, S.W.7
  • 36
    • 0020608458 scopus 로고
    • Treatment of (NZB/ NZW)F1 disease with anti-I-A monoclonal antibodies
    • Adelman NE, Watling DL, McDevitt HO: Treatment of (NZB/ NZW)F1 disease with anti-I-A monoclonal antibodies. J Exp Med 158:1350-1355, 1983
    • (1983) J Exp Med , vol.158 , pp. 1350-1355
    • Adelman, N.E.1    Watling, D.L.2    McDevitt, H.O.3
  • 37
    • 0021943982 scopus 로고
    • Type-II collagen-induced arthritis in mice. III. Suppression of arthritis by using monoclonal and polyclonal anti-Ia antisera
    • Wooley PH, Luthra HS, Lafuse WP, Huse A, Stuart JM, David CS: Type-II collagen-induced arthritis in mice. III. Suppression of arthritis by using monoclonal and polyclonal anti-Ia antisera. J Immunol 134:2366-2374, 1985
    • (1985) J Immunol , vol.134 , pp. 2366-2374
    • Wooley, P.H.1    Luthra, H.S.2    Lafuse, W.P.3    Huse, A.4    Stuart, J.M.5    David, C.S.6
  • 38
    • 0027275821 scopus 로고
    • Maternal-fetal disparity in HLA class II alloantigens and the pregnancy-induced amelioration of rheumatoid arthritis
    • Nelson JL, Hughes KA, Smith AG, Nisperos BB, Branchaud AM, Hansen JA: Maternal-fetal disparity in HLA class II alloantigens and the pregnancy-induced amelioration of rheumatoid arthritis. N Engl J Med 329:466-471, 1993
    • (1993) N Engl J Med , vol.329 , pp. 466-471
    • Nelson, J.L.1    Hughes, K.A.2    Smith, A.G.3    Nisperos, B.B.4    Branchaud, A.M.5    Hansen, J.A.6
  • 43
    • 0021855053 scopus 로고
    • Human placenta-eluted gammaglobulins in immunomodulating treatment of rheumatoid arthritis
    • Combe B, Cosso B, Clot J, Bonneau M, Sany J: Human placenta-eluted gammaglobulins in immunomodulating treatment of rheumatoid arthritis. Am J Med 78:920-928, 1985
    • (1985) Am J Med , vol.78 , pp. 920-928
    • Combe, B.1    Cosso, B.2    Clot, J.3    Bonneau, M.4    Sany, J.5
  • 44
    • 0023216719 scopus 로고
    • Identification of class II HLA alloantibodies in placenta-eluted gamma globulins used for treating rheumatoid arthritis
    • Moynier M, Cosso B, Brochier J, Clot J: Identification of class II HLA alloantibodies in placenta-eluted gamma globulins used for treating rheumatoid arthritis. Arthritis Rheum 30:375-381, 1987
    • (1987) Arthritis Rheum , vol.30 , pp. 375-381
    • Moynier, M.1    Cosso, B.2    Brochier, J.3    Clot, J.4
  • 45
    • 0344855995 scopus 로고
    • Treatment of rheumatoid arthritis by murine anitiidiotypic monoclonal antibodies to a syngeneic anti-HLA class II monoclonal antibody
    • Fiocco U, Cozzi L, Cozzi E: Treatment of rheumatoid arthritis by murine anitiidiotypic monoclonal antibodies to a syngeneic anti-HLA class II monoclonal antibody. Br J Rheumatol 30:90-94, 1991
    • (1991) Br J Rheumatol , vol.30 , pp. 90-94
    • Fiocco, U.1    Cozzi, L.2    Cozzi, E.3
  • 46
    • 0030000365 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis by immunization with mononuclear white blood cells: Results of a preliminary trial
    • Smith JB, Fort JG: Treatment of rheumatoid arthritis by immunization with mononuclear white blood cells: results of a preliminary trial. J Rheumatol 23:220-225, 1996
    • (1996) J Rheumatol , vol.23 , pp. 220-225
    • Smith, J.B.1    Fort, J.G.2
  • 47
    • 0000413349 scopus 로고
    • Safety and immunogenecity of a single intramuscular injection of a synthetic HLA-DR4/1-peptide vaccine with alum adjuvant in rheumatoid arthritis patients
    • Pratt W, Heck L, Moreland E, Koopman W, Parkhill T, Pratt G, Hanavan S, Wehner N, Holcenberg J, Winkelhake J: Safety and immunogenecity of a single intramuscular injection of a synthetic HLA-DR4/1-peptide vaccine with alum adjuvant in rheumatoid arthritis patients (abstract). Arthritis Rheum 38 (suppl 9):S281, 1995
    • (1995) Arthritis Rheum , vol.38 , Issue.SUPPL. 9
    • Pratt, W.1    Heck, L.2    Moreland, E.3    Koopman, W.4    Parkhill, T.5    Pratt, G.6    Hanavan, S.7    Wehner, N.8    Holcenberg, J.9    Winkelhake, J.10
  • 48
    • 0028861236 scopus 로고
    • Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis
    • Arend WP, Dayer J-M: Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis. Arthritis Rheum 38:151-160, 1995
    • (1995) Arthritis Rheum , vol.38 , pp. 151-160
    • Arend, W.P.1    Dayer, J.-M.2
  • 49
    • 0028226982 scopus 로고
    • Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis
    • Williams RO, Mason LJ, Feldmann M, Maini RN: Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis. Proc Natl Acad Sci 91:2762-2766, 1994
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 2762-2766
    • Williams, R.O.1    Mason, L.J.2    Feldmann, M.3    Maini, R.N.4
  • 50
    • 0027371372 scopus 로고
    • The effect of an interleukin-1 receptor antagonist protein on type II collagen-induced arthritis and antigen-induced arthritis in mice
    • Wooley PH, Whalen JD, Chapman DL, Berger AE, Richard KA, Aspar DG, Staite ND: The effect of an interleukin-1 receptor antagonist protein on type II collagen-induced arthritis and antigen-induced arthritis in mice. Arthritis Rheum 36:1305-1314, 1993
    • (1993) Arthritis Rheum , vol.36 , pp. 1305-1314
    • Wooley, P.H.1    Whalen, J.D.2    Chapman, D.L.3    Berger, A.E.4    Richard, K.A.5    Aspar, D.G.6    Staite, N.D.7
  • 51
    • 0028957027 scopus 로고
    • Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD-4
    • Williams RO, Ghrayeb J, Feldman M, Maini RN: Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD-4. Immunology 84:433-439, 1995
    • (1995) Immunology , vol.84 , pp. 433-439
    • Williams, R.O.1    Ghrayeb, J.2    Feldman, M.3    Maini, R.N.4
  • 52
    • 0027422060 scopus 로고
    • Influence of a recombinant human soluble tumor necrosis factor receptor FC fusion protein on type II collagen-induced arthritis in mice
    • Wooley PH, Dutcher J, Widmer MB, Gillis S: Influence of a recombinant human soluble tumor necrosis factor receptor FC fusion protein on type II collagen-induced arthritis in mice. J Immunol 11:6602-6607, 1993
    • (1993) J Immunol , vol.11 , pp. 6602-6607
    • Wooley, P.H.1    Dutcher, J.2    Widmer, M.B.3    Gillis, S.4
  • 53
    • 0028342682 scopus 로고
    • Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment
    • Van den Berg WB, Joosten LM, Helsen M, van de Loo FA: Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment. Clin Exp Immunol 95:237-243, 1994
    • (1994) Clin Exp Immunol , vol.95 , pp. 237-243
    • Van den Berg, W.B.1    Joosten, L.M.2    Helsen, M.3    Van de Loo, F.A.4
  • 55
    • 0030176045 scopus 로고    scopus 로고
    • Long-term protection against the effects of tumor necrosis factor by controlled delivery of the soluble p55 TNF receptor
    • Eliaz R, Wallach D, Kost J: Long-term protection against the effects of tumor necrosis factor by controlled delivery of the soluble p55 TNF receptor. Cytokine 8:482-487, 1996
    • (1996) Cytokine , vol.8 , pp. 482-487
    • Eliaz, R.1    Wallach, D.2    Kost, J.3
  • 56
    • 0029875804 scopus 로고    scopus 로고
    • Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: A comparative study using anti-TNFα, anti-IL-1α/β, and IL-1Ra
    • Joosten LAB, Helsen MMA, van de Loo FAJ, van den Berg WB: Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: a comparative study using anti-TNFα, anti-IL-1α/β, and IL-1Ra. Arthritis Rheum 39:797-809, 1996
    • (1996) Arthritis Rheum , vol.39 , pp. 797-809
    • Lab, J.1    Helsen, M.M.A.2    Van de Loo, F.A.J.3    Van den Berg, W.B.4
  • 57
    • 0028891167 scopus 로고
    • Role of interleukin-1, tumor necrosis factor α, and interleukin-6 in cartilage proteoglycan metabolism and destruction: Effect of in situ blocking in murine antigen- and zymosan-induced arthritis
    • Van de Loo FAJ, Joosten LAB, van Lent PLEM, Arntz OJ, van den Berg WB: Role of interleukin-1, tumor necrosis factor α, and interleukin-6 in cartilage proteoglycan metabolism and destruction: effect of in situ blocking in murine antigen- and zymosan-induced arthritis. Arthritis Rheum 38:164-172, 1995
    • (1995) Arthritis Rheum , vol.38 , pp. 164-172
    • Van de Loo, F.A.J.1    Joosten, L.A.B.2    Van Lent, P.L.E.M.3    Arntz, O.J.4    Van den Berg, W.B.5
  • 58
    • 0025787689 scopus 로고
    • Interleukin-1 receptor antagonist: A new member of the interleukin family
    • Arend WP: Interleukin-1 receptor antagonist: a new member of the interleukin family. J Clin Invest 88:1445-1451, 1991
    • (1991) J Clin Invest , vol.88 , pp. 1445-1451
    • Arend, W.P.1
  • 59
    • 0029943271 scopus 로고    scopus 로고
    • Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis
    • Campion GV, Lebsack ME, Lookabaugh J, Gordon G, Catalano M, and the IL-1Ra Arthritis Study Group: Dose-range and dose-frequency study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis. Arthritis Rheum 39:1092-1101, 1996
    • (1996) Arthritis Rheum , vol.39 , pp. 1092-1101
    • Campion, G.V.1    Lebsack, M.E.2    Lookabaugh, J.3    Gordon, G.4    Catalano, M.5
  • 60
    • 0000168402 scopus 로고    scopus 로고
    • Treatment with recombinant human interleukin-1 receptor antagonist (rhuIL-1ra) in rheumatoid arthritis: Results of a randomized double-blind, placebo-controlled multicenter
    • Bresnihan B, on behalf of the collaborating investigators, Lookabaugh J, Witt K, Musikic P: Treatment with recombinant human interleukin-1 receptor antagonist (rhuIL-1ra) in rheumatoid arthritis: results of a randomized double-blind, placebo-controlled multicenter (abstract). Arthritis Rheum 39 (suppl 9)S73, 1996
    • (1996) Arthritis Rheum , vol.39 , Issue.SUPPL. 9
    • Bresnihan, B.1    Lookabaugh, J.2    Witt, K.3    Musikic, P.4
  • 62
    • 0025954301 scopus 로고
    • Purification and characterization of a novel soluble receptor for interleukin-1
    • Symons JA, Eastgate JA, Duff GW: Purification and characterization of a novel soluble receptor for interleukin-1. J Exp Med 174:1251-1254, 1991
    • (1991) J Exp Med , vol.174 , pp. 1251-1254
    • Symons, J.A.1    Eastgate, J.A.2    Duff, G.W.3
  • 63
    • 0028172557 scopus 로고
    • Binding of the IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble IL-1 receptors by synovial fluids
    • Arend WP, Malyak M, Smith MF Jr, Whisenend TD, Slack JL, Sims JE, Giri JG, Dower SK: Binding of the IL-1 alpha, IL-1 beta, and IL-1 receptor antagonist by soluble IL-1 receptors and levels of soluble IL-1 receptors by synovial fluids. J Immunol 153:4766-4774, 1994
    • (1994) J Immunol , vol.153 , pp. 4766-4774
    • Arend, W.P.1    Malyak, M.2    Smith Jr., M.F.3    Whisenend, T.D.4    Slack, J.L.5    Sims, J.E.6    Giri, J.G.7    Dower, S.K.8
  • 64
    • 0001925856 scopus 로고
    • Phase I study of recombinant human interleukin-1 receptor (rhu IL-1R) administered intra-articularly in active rheumatoid arthritis
    • Drevlow B, Capezio J, Lovis R, Jacobs C, Landay A, Pope RM: Phase I study of recombinant human interleukin-1 receptor (rhu IL-1R) administered intra-articularly in active rheumatoid arthritis (abstract). Arthritis Rheum 36 (suppl 9):S39, 1993
    • (1993) Arthritis Rheum , vol.36 , Issue.SUPPL. 9
    • Drevlow, B.1    Capezio, J.2    Lovis, R.3    Jacobs, C.4    Landay, A.5    Pope, R.M.6
  • 68
    • 0025266158 scopus 로고
    • Analysis of improvement in individual rheumatoid arthritis patients treated with disease-modifying antirheumatic drugs, based on the findings in patients treated with placebo
    • Paulus HE, Egger MJ, Ward JR, Williams HJ, and the Cooperative Systematic Studies of Rheumatic Diseases Group: Analysis of improvement in individual rheumatoid arthritis patients treated with disease-modifying antirheumatic drugs, based on the findings in patients treated with placebo. Arthritis Rheum 33:477-484, 1990
    • (1990) Arthritis Rheum , vol.33 , pp. 477-484
    • Paulus, H.E.1    Egger, M.J.2    Ward, J.R.3    Williams, H.J.4
  • 69
    • 0028143212 scopus 로고
    • Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldmann M, Long-Fox A, Charles P, Bijl H, Woody JN: Repeated therapy with monoclonal antibody to tumour necrosis factor α (cA2) in patients with rheumatoid arthritis. Lancet 344:1125-1127, 1994
    • (1994) Lancet , vol.344 , pp. 1125-1127
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3    Long-Fox, A.4    Charles, P.5    Bijl, H.6    Woody, J.N.7
  • 70
    • 0029896957 scopus 로고    scopus 로고
    • Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor α monoclonal antibody treatment inpatients with rheumatoid arthritis
    • Tak PP, Taylor PC, Breedveld FC, Smeets TJM, Daha MR, Kluin PM, Meinders AE, Maini RN: Decrease in cellularity and expression of adhesion molecules by anti-tumor necrosis factor α monoclonal antibody treatment inpatients with rheumatoid arthritis. Arthritis Rheum 39:1077-1081, 1996
    • (1996) Arthritis Rheum , vol.39 , pp. 1077-1081
    • Tak, P.P.1    Taylor, P.C.2    Breedveld, F.C.3    Smeets, T.J.M.4    Daha, M.R.5    Kluin, P.M.6    Meinders, A.E.7    Maini, R.N.8
  • 71
    • 0029671297 scopus 로고    scopus 로고
    • In vivo blockade of TNF-α by intravenous infusion of a chimeric monoclonal TNF-α antibody in patients with rheumatoid arthritis: Short-term cellular and molecular effects
    • Lorenz H-M, Antoni C, Valerius T, Repp R, Grünke M, Schwerdtner N, NüBlein H, Woody J, Kalden JR, Manger B: In vivo blockade of TNF-α by intravenous infusion of a chimeric monoclonal TNF-α antibody in patients with rheumatoid arthritis: short-term cellular and molecular effects. J Immunol 156:1646-1653, 1996
    • (1996) J Immunol , vol.156 , pp. 1646-1653
    • Lorenz, H.-M.1    Antoni, C.2    Valerius, T.3    Repp, R.4    Grünke, M.5    Schwerdtner, N.6    Nüblein, H.7    Woody, J.8    Kalden, J.R.9    Manger, B.10
  • 72
    • 0030013609 scopus 로고    scopus 로고
    • Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor α antibody in rheumatoid arthritis
    • Paleolog EM, Hunt M, Elliott MJ, Feldmann M, Maini RN, Woody JN: Deactivation of vascular endothelium by monoclonal anti-tumor necrosis factor α antibody in rheumatoid arthritis. Arthritis Rheum 39:1082-1091, 1996
    • (1996) Arthritis Rheum , vol.39 , pp. 1082-1091
    • Paleolog, E.M.1    Hunt, M.2    Elliott, M.J.3    Feldmann, M.4    Maini, R.N.5    Woody, J.N.6
  • 75
    • 0028299220 scopus 로고
    • Adherence of neutrophils induces release of soluble tumor necrosis factor receptor forms
    • Lantz M, Bjornberg F, Olsson I, Richter J: Adherence of neutrophils induces release of soluble tumor necrosis factor receptor forms. J Immunol 152:1362-1369, 1994
    • (1994) J Immunol , vol.152 , pp. 1362-1369
    • Lantz, M.1    Bjornberg, F.2    Olsson, I.3    Richter, J.4
  • 76
    • 0027198002 scopus 로고
    • Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists
    • Mohler KM, Torrance DS, Smith CA, Goodwin RG, Stremler KE, Fung VP, Madani H, Widmer MB: Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J Immunol 151:1548-1561, 1993
    • (1993) J Immunol , vol.151 , pp. 1548-1561
    • Mohler, K.M.1    Torrance, D.S.2    Smith, C.A.3    Goodwin, R.G.4    Stremler, K.E.5    Fung, V.P.6    Madani, H.7    Widmer, M.B.8
  • 77
    • 0029858740 scopus 로고    scopus 로고
    • Recombinant soluble tumor necrosis factor receptor (p80) fusion protein: Toxicity and dose finding trial in refractory rheumatoid arthritis
    • Moreland LW, Margolies GR, Heck LW, Saway PA, Blosch C, Hanna R, Koopman WJ: Recombinant soluble tumor necrosis factor receptor (p80) fusion protein: toxicity and dose finding trial in refractory rheumatoid arthritis. J Rheumatol 23:1849-1855, 1996
    • (1996) J Rheumatol , vol.23 , pp. 1849-1855
    • Moreland, L.W.1    Margolies, G.R.2    Heck, L.W.3    Saway, P.A.4    Blosch, C.5    Hanna, R.6    Koopman, W.J.7
  • 79
    • 0001649520 scopus 로고    scopus 로고
    • Efficacy of tumor necrosis factor binding protein (TNF-bp) in streptococcal cell wall-induced reaction model of arthritis
    • Evans RJ, McCabe JG, Bendele AM, Kieft GL, McAbee TJ, Edwards CK III: Efficacy of tumor necrosis factor binding protein (TNF-bp) in streptococcal cell wall-induced reaction model of arthritis (abstract). Arthritis Rheum 39 (suppl 9):S284, 1996
    • (1996) Arthritis Rheum , vol.39 , Issue.SUPPL. 9
    • Evans, R.J.1    McCabe, J.G.2    Bendele, A.M.3    Kieft, G.L.4    McAbee, T.J.5    Edwards III, C.K.6
  • 83
    • 0026348703 scopus 로고
    • Multicenter double-blind trial of interferon-γ versus placebo in the treatment of rheumatoid arthritis
    • Lemmel EM, Gaus W, Hofschneider PH: Multicenter double-blind trial of interferon-γ versus placebo in the treatment of rheumatoid arthritis. Arthritis Rheum 34:1621-1622, 1991
    • (1991) Arthritis Rheum , vol.34 , pp. 1621-1622
    • Lemmel, E.M.1    Gaus, W.2    Hofschneider, P.H.3
  • 85
    • 0026767264 scopus 로고
    • Recombinant human interferon gamma in the treatment of rheumatoid arthritis: Double blind placebo controlled study
    • Machold KP, Neumann K, Smolen JS: Recombinant human interferon gamma in the treatment of rheumatoid arthritis: double blind placebo controlled study. Ann Rheum Dis 51:1039-1043, 1992
    • (1992) Ann Rheum Dis , vol.51 , pp. 1039-1043
    • Machold, K.P.1    Neumann, K.2    Smolen, J.S.3
  • 86
    • 0027402917 scopus 로고
    • Treatment of severe rheumatoid arthritis by anti-interleukin-6 monoclonal antibody
    • Wendling D, Racadot E, Wijdenes J: Treatment of severe rheumatoid arthritis by anti-interleukin-6 monoclonal antibody. J Rheumatol 20:259-262, 1993
    • (1993) J Rheumatol , vol.20 , pp. 259-262
    • Wendling, D.1    Racadot, E.2    Wijdenes, J.3
  • 87
    • 0026530464 scopus 로고
    • IL-10, T lymphocyte inhibitor of human blood cell production of IL-1 and tumor necrosis factor
    • Ralph P, Nakoinz I, Sampson-Johannes A, Fong S, Lowe D, Min HY, Lin L: IL-10, T lymphocyte inhibitor of human blood cell production of IL-1 and tumor necrosis factor. J Immunol 148:808-814, 1992
    • (1992) J Immunol , vol.148 , pp. 808-814
    • Ralph, P.1    Nakoinz, I.2    Sampson-Johannes, A.3    Fong, S.4    Lowe, D.5    Min, H.Y.6    Lin, L.7
  • 88
    • 0027517422 scopus 로고
    • Interleukin (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes: Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide
    • Cassatella MA, Meda L, Bonora S, Ceska M, Constantin G: Interleukin (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes: evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide. J Exp Med 178:2207-2211, 1993
    • (1993) J Exp Med , vol.178 , pp. 2207-2211
    • Cassatella, M.A.1    Meda, L.2    Bonora, S.3    Ceska, M.4    Constantin, G.5
  • 89
    • 0028855894 scopus 로고
    • IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes
    • Lacraz S, Nicod LP, Chicheportiche R, Welgus HG, Dayer JM: IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes. J Clin Invest 96:2304-2310, 1995
    • (1995) J Clin Invest , vol.96 , pp. 2304-2310
    • Lacraz, S.1    Nicod, L.P.2    Chicheportiche, R.3    Welgus, H.G.4    Dayer, J.M.5
  • 90
    • 0026503448 scopus 로고
    • Coordinated antiinflammatory effects of interleukin-4: Interieukin-4 suppresses interleukin 1 production but upregulates gene expression and synthesis of interleukin-1 receptor antagonist
    • Vannier E, Miller LC, Dinarello CA: Coordinated antiinflammatory effects of interleukin-4: interieukin-4 suppresses interleukin 1 production but upregulates gene expression and synthesis of interleukin-1 receptor antagonist. Proc Natl Acad Sci U S A 89:4076-4080, 1992
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 4076-4080
    • Vannier, E.1    Miller, L.C.2    Dinarello, C.A.3
  • 91
    • 0027370379 scopus 로고
    • Suppression of monocyte function and differential regulation of IL-1 and IL-1ra by IL-4 contribute to resolution of experimental arthritis
    • Allen JB, Wong HL, Costa GL, Bienkowski MJ, Wahl SM: Suppression of monocyte function and differential regulation of IL-1 and IL-1ra by IL-4 contribute to resolution of experimental arthritis. J Immunol 151:4344-4351, 1993
    • (1993) J Immunol , vol.151 , pp. 4344-4351
    • Allen, J.B.1    Wong, H.L.2    Costa, G.L.3    Bienkowski, M.J.4    Wahl, S.M.5
  • 93
    • 0024996678 scopus 로고
    • Suppression of adjuvant arthritis in Lewis rats by oral administration of type II collagen
    • Zhang ZJ, Lee CSY, Lider O, Weiner HL: Suppression of adjuvant arthritis in Lewis rats by oral administration of type II collagen. J Immunol 145:2489-2493, 1990
    • (1990) J Immunol , vol.145 , pp. 2489-2493
    • Zhang, Z.J.1    Lee, C.S.Y.2    Lider, O.3    Weiner, H.L.4
  • 97
    • 0030572184 scopus 로고    scopus 로고
    • Adhesion molecules - Part I
    • Frenette PS, Wagner DD: Adhesion molecules - part I. N Engl J Med 334:1526-1529, 1996
    • (1996) N Engl J Med , vol.334 , pp. 1526-1529
    • Frenette, P.S.1    Wagner, D.D.2
  • 98
  • 99
    • 0026725640 scopus 로고
    • Amelioration of antigen-induced arthritis in rabbits treated with monoclonal antibodies to leukocyte adhesion molecules
    • Jasin HE, Lightfoot E, Davis LS, Rothlein R, Faanes RB, Lipsky PE: Amelioration of antigen-induced arthritis in rabbits treated with monoclonal antibodies to leukocyte adhesion molecules. Arthritis Rheum 35:541-549, 1992
    • (1992) Arthritis Rheum , vol.35 , pp. 541-549
    • Jasin, H.E.1    Lightfoot, E.2    Davis, L.S.3    Rothlein, R.4    Faanes, R.B.5    Lipsky, P.E.6
  • 102
    • 0028937951 scopus 로고
    • Induction of persistent T cell hyporesponsiveness in vivo by monoclonal antibody to ICAM-1 in patients with rheumatoid arthritis
    • Davis LS, Kavanaugh AF, Nichols LA, Lipsky PE: Induction of persistent T cell hyporesponsiveness in vivo by monoclonal antibody to ICAM-1 in patients with rheumatoid arthritis. J Immunol 154:3525-3537, 1995
    • (1995) J Immunol , vol.154 , pp. 3525-3537
    • Davis, L.S.1    Kavanaugh, A.F.2    Nichols, L.A.3    Lipsky, P.E.4
  • 103
    • 0000196397 scopus 로고
    • Retreatment of rheumatoid arthritis patients with an anti-ICAM-1 monoclonal antibody (abstract)
    • Kavanaugh A, Davis L, Nichols L, Lipsky P: Retreatment of rheumatoid arthritis patients with an anti-ICAM-1 monoclonal antibody (abstract). Arthritis Rheum (suppl 9)38:S280, 1995
    • (1995) Arthritis Rheum (Suppl 9) , vol.38
    • Kavanaugh, A.1    Davis, L.2    Nichols, L.3    Lipsky, P.4
  • 106
    • 0027493906 scopus 로고
    • In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD4, gp39
    • Foy TM, Shepherd DM, Durie FH, Aruffo A, Ledbetter JA, Noelle RJ: In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD4, gp39. J Exp Med 178:1567-1575, 1993
    • (1993) J Exp Med , vol.178 , pp. 1567-1575
    • Foy, T.M.1    Shepherd, D.M.2    Durie, F.H.3    Aruffo, A.4    Ledbetter, J.A.5    Noelle, R.J.6
  • 107
    • 0027816953 scopus 로고
    • Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40
    • Durie FH, Fava RA, Foy TM, Aruffo A, Ledbetter JA, Noelle RJ: Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40. Science 261:1328-1330, 1993
    • (1993) Science , vol.261 , pp. 1328-1330
    • Durie, F.H.1    Fava, R.A.2    Foy, T.M.3    Aruffo, A.4    Ledbetter, J.A.5    Noelle, R.J.6
  • 108
    • 0028123024 scopus 로고
    • Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease
    • Durie FH, Aruffo A, Ledbetter J, Crassi KM, Green WR, Fast LD, Noelle RJ: Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease. J Clin Invest 94:1333-1338, 1994
    • (1994) J Clin Invest , vol.94 , pp. 1333-1338
    • Durie, F.H.1    Aruffo, A.2    Ledbetter, J.3    Crassi, K.M.4    Green, W.R.5    Fast, L.D.6    Noelle, R.J.7
  • 111
    • 0028483990 scopus 로고
    • Treatment of murine lupus with CTLA4Ig
    • Finck BK, Linsley PS, Wofsy D: Treatment of murine lupus with CTLA4Ig. Science 265:1225-1227, 1994
    • (1994) Science , vol.265 , pp. 1225-1227
    • Finck, B.K.1    Linsley, P.S.2    Wofsy, D.3
  • 112
    • 0029162499 scopus 로고
    • Collagen induced arthritis in the BB rat: Prevention of disease by treatment with CTLA-4-Ig
    • Knoerzer DB, Karr RW, Schwartz BD, Mengle-Gaw LJ: Collagen induced arthritis in the BB rat: prevention of disease by treatment with CTLA-4-Ig. J Clin Invest 96:987-993, 1995
    • (1995) J Clin Invest , vol.96 , pp. 987-993
    • Knoerzer, D.B.1    Karr, R.W.2    Schwartz, B.D.3    Mengle-Gaw, L.J.4
  • 113
    • 0024337629 scopus 로고
    • Systemic administration of TIMP in the treatment of collagen-induced arthritis in mice
    • Carmichael DF, Stricklin GP, Stuart JM: Systemic administration of TIMP in the treatment of collagen-induced arthritis in mice. Agents Actions 27:378-379, 1989
    • (1989) Agents Actions , vol.27 , pp. 378-379
    • Carmichael, D.F.1    Stricklin, G.P.2    Stuart, J.M.3
  • 114
    • 0023597374 scopus 로고
    • Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts
    • Clark SD, Kobayashi DK, Welgus HG: Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts. J Clin Invest 890:1280-1288, 1987
    • (1987) J Clin Invest , vol.890 , pp. 1280-1288
    • Clark, S.D.1    Kobayashi, D.K.2    Welgus, H.G.3
  • 115
    • 0027133240 scopus 로고
    • In vivo suppression of immune complex induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2
    • Mulligan MS, Desrochers PE, Chinnaiyan AM, Gibbs DF, Varani J, Johnson KJ, Weiss SJ: In vivo suppression of immune complex induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2. Proc Natl Acad Sci U S A 90:11523-111527, 1993
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 11523-111527
    • Mulligan, M.S.1    Desrochers, P.E.2    Chinnaiyan, A.M.3    Gibbs, D.F.4    Varani, J.5    Johnson, K.J.6    Weiss, S.J.7
  • 116
    • 0029891449 scopus 로고    scopus 로고
    • Paradoxical effects of a synthetic metalloproteinase inhibitor that blocks both p55 and p75 TNF receptor shedding and TNFα processing in RA synovial membrane cell cultures
    • Williams LM, Gibbons DL, Gearing A, Maini RN, Feldman M, Brennan FM: Paradoxical effects of a synthetic metalloproteinase inhibitor that blocks both p55 and p75 TNF receptor shedding and TNFα processing in RA synovial membrane cell cultures. J Clin Invest 97:2833-2841, 1996
    • (1996) J Clin Invest , vol.97 , pp. 2833-2841
    • Williams, L.M.1    Gibbons, D.L.2    Gearing, A.3    Maini, R.N.4    Feldman, M.5    Brennan, F.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.