Potentiation to vasodilators by nitric oxide synthase blockade in superior mesenteric but not hepatic artery

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 272, Issue 3 35-3, 1997, Pages

  Macedo, M Paula ^a   Lautt, W Wayne ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

adenosine; intestine; isoproterenol; liver

Indexed keywords

ADENOSINE; ARGININE; ISOPRENALINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PENTOBARBITAL; VASODILATOR AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTERY TONE; ARTICLE; CAT; CONTROLLED STUDY; FEMALE; HEPATIC ARTERY; MALE; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; SUPERIOR MESENTERIC ARTERY;

EID: 0030990211     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1997.272.3.g507     Document Type: Article

References (32)

1. Browser, D. J., R. T. Mathie, I. S. Benjamin, and B. Alexander. The transhepatic action of ATP on the hepatic arterial and portal venous vascular beds of the rabbit: the role of nitric oxide. Br. J. Pharmacol. 113: 987-993, 1994.
2. Busse, R., P. Ulrich, A. Mulsch, and E. Bassenge. Modulation of the vasodilator action of SIN-1 by the endothelium. J. Cardiovasc. Pharmacol. 14, Suppl. 11: S81-S85, 1989.
3. Eckly, A. E., and C. Lugnier. Role of phosphodiesterases III and IV in the modulation of vascular cyclic AMP content by the NO/cyclic GMP pathway. Br. J. Pharmacol. 113: 445-450, 1994.
4. Ezzat, W. R., and W. W. Lautt. Hepatic arterial pressure-flow autoregulation is adenosine mediated. Am. J. Physiol. 252 (Heart Circ. Physiol. 21): H836-H845, 1987.
5. G-nitro-L-arginine methyl ester on vasodilator responses to acetylcholine, 5′-N-ethylcarboxamidoadenosine or salbutamol in conscious rats. Br. J. Pharmacol. 103: 1725-1732, 1991.
6. Greenblatt, E. P., A. L. Loeb, and D. E. Longnecker. Marked regional heterogeneity in the magnitude of EDRF/NO-mediated vascular tone in awake rats. J. Cardiovasc. Pharmacol. 21: 235-240, 1993.
7. Hernandez, F., S. P. H. Alexander, and D. A. Kendall. Forskolin and 3-isobutyl-1-methylxanthine increase basal and sodium nitroprusside-elevated cyclic GMP levels in adult guinea pig cerebellar slices. J. Neurochem. 62: 2212-2218, 1994.
8. Heuze-Jouber, L., P. Mennecier, S. Simonet, M. Laubie, and T. J. Verbeuren. Effect of vasodilators, including nitric oxide, on the release of cGMP and cAMP in the isolated perfused rat kidney. Eur. J. Pharmacol. 220: 161-171, 1992.
9. Ignarro, L. J. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circ. Res. 65: 1-21, 1989.
10. Jacobson, E. D., and W. W. Pawlik. Adenosine regulation of mesenteric vasodilation. Gastroenterology 107: 1168-1180, 1994.
11. Komas, N., C. Lugnier, and J. C. Stoclet. Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors. Br. J. Pharmacol. 104: 495-503, 1991.
12. Lautt, W. W. Autoregulation of superior mesenteric artery is blocked by adenosine antagonism. Can. J. Physiol. Pharmacol. 64: 1291-1295, 1986.
13. Lautt, W. W., D. J. Legare, and M. S. d'Almeida. Adenosine as putative regulator of hepatic arterial flow (the buffer response). Am. J. Physiol. 248 (Heart Circ. Physiol. 17): H331-H338, 1985.
14. Li, J., and C. Iadecola. Nitric oxide and adenosine mediate vasodilation during functional activation in cerebellar cortex. Neuropharmacology 33: 1453-1461, 1994.
15. 2+ by cAMP in vascular smooth muscle cells. Am. J. Physiol. 258 (Cell Physiol. 27): C399-C407, 1990.
16. Luscher, T., V. Richard, and Z. Yang. Interaction between endothelium-derived nitric oxide and SIN-1 in human and porcine blood vessels. J. Cardiovasc. Pharmacol. 14, Suppl. 11: S76-S80, 1989.
17. Macedo, M. P., and W. W. Lautt. Nitric oxide synthase antagonism potentiates pressure-flow autoregulation in the superior mesenteric artery. Proc. West. Pharmacol. Soc. 38: 33-34, 1995.
18. Macedo, M. P., and W. W. Lautt. Shear-induced modulation by nitric oxide of sympathetic nerves in mesenteric artery. Can. J. Physiol. Pharmacol. 74: 692-700, 1996.
19. 2-purinoceptors. Br. J. Pharmacol. 103: 1103-1107, 1991.
20. Mathie, R. T., V. Ralevic, B. Alexander, and G. Burnstock. Nitric oxide is the mediator of ATP-induced dilation of the rabbit hepatic arterial vascular bed. Br. J. Pharmacol. 103: 1603-1606, 1991.
21. Maurice, D. H., D. Crankshaw, and R. J. Haslam. Synergetic actions of nitrovasodilators and isoprenaline on rat aortic smooth muscle. Eur. J. Pharmacol. 192: 235-242, 1991.
22. Maurice, D. H., and R. J. Haslam. Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP. Mol. Pharmacol. 37: 671-681, 1990.
23. Murthy, K. S., and G. M. Makhlouf. Interaction of cA-kinase and cG-kinase in mediating relaxation of dispersed smooth muscle cells. Am. J. Physiol. 268 (Cell Physiol. 37): C171-C180, 1995.
24. G-nitro-L-arginine methyl ester attenuates vasodilator responses to acetylcholine but enhances those to sodium nitroprusside. J. Pharm. Pharmacol. 43: 871-874, 1991.
25. Ralevic, V., P. Milner, K. A. Kirkpatrick, and G. Burnstock. Flow-induced release of adenosine 5′-triphosphate from endothelial cells of the rat mesenteric arterial bed. Experientia 48: 31-34, 1992.
26. Rees, D. D., R. M. J. Palmer, H. F. Hodson, and S. Moncada. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol. 101: 746-752, 1990.
27. Shirasaki, Y., and C. Su. Endothelium removal augments vasodilation by sodium nitroprusside and sodium nitrate. Eur J. Pharmacol. 114: 93-96, 1985.
28. Taira, N., Y. Yabuuchi, and S. Yamashita. Profile of β-adrenoceptors in femoral, superior mesenteric and renal vasculature beds of dogs. Br. J. Pharmacol. 59: 577-583, 1977.
29. Taylor, P. D., B. B. Oon, C. R. Thomas, and L. Poston. Prevention by insulin treatment of endothelium dysfunction but not enhanced noradrenaline-induced contractility in mesenteric resistance arterioles from streptozotocin-induced diabetic rats. Br. J. Pharmacol. 111: 35-41, 1994.
30. 2+-dependent intracellular signalling mechanisms in brain capillary endothelial cells. J. Neurochem. 62: 2269-2274, 1994.
31. White, B., and D. C. Klein. Stimulation of cyclic GMP accumulation by sodium nitroprusside is potentiated via a Gs mechanism in intact pinealocytes. J. Neurochem. 62: 711-717, 1995.
32. Woolfson, R. G., V. C. Patel, G. H. Neild, and D. M. Yellow. Inhibition of nitric oxide synthesis reduces infarct size by an adenosine-dependent mechanism. Circulation 91: 1545-1551, 1995.