In vivo effects of recombinant human granulocyte colony-stimulating factor on neutrophil oxidative functions in normal human volunteers

Journal of Infectious Diseases

Volumn 175, Issue 5, 1997, Pages 1184-1192

  Allen, Robert C ^a   Stevens, Paul R ^a   Price, Thomas H ^a   Chatta, Gurkamal S ^a   Dale, David C ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

MYELOPEROXIDASE; N(G) METHYLARGININE; OPSONIN; OXIDOREDUCTASE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; SUPEROXIDE DISMUTASE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HUMAN; HUMAN EXPERIMENT; LEUKOCYTOSIS; MALE; NEUTROPHIL; NORMAL HUMAN; OXIDATION; PHAGOCYTE; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030990161     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/595866     Document Type: Article

References (18)

1. Demetri GD, Griffin JD. Granulocyte colony-stimulating factor and its receptor. Blood 1991;78:2791-808.
2. Roilides E, Walsh TJ, Pizzo PA, Rubin M. Granulocyte colony-stimulating factor enhances the phagocytic and bactericidal activity of normal and defective human neutrophils. J Infect Dis 1991;163:579-83.
3. Roilides E, Uhlig K, Venzon D, Pizzo PA, Walsh TJ. Enhancement of oxidative response and damage caused by human neutrophils to Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferon. Infect Immun 1993;61:1185-93.
4. Kerst JM, van de Winkel JGJ, Evans AH, et al. Granulocyte colony-stimulating factor induces hFcγRI (CD64 antigen)-positive neutrophils via an effect on myeloid precursor cells. Blood 1993;81:1457-64.
5. Kerst JM, de Haas M, van der School CE, et al. Recombinant granulocyte colony-stimulating factor administration to healthy volunteers: induction of immunophenotypically and functionally altered neutrophils via an effect on myeloid progenitor cells. Blood 1993;82:3265-72.
6. Valerius T, Repp R, de Wit TPM, et al. Involvement of the high-affinity receptor for IgG (FcγRI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy. Blood 1993;82:931-9.
7. Yasuda H, Ajiki L, Shimozato T, et al. Therapeutic efficacy of granulocyte colony-stimulating factor alone and in combination with antibiotics against Pseudomonas aeruginosa infections in mice. Infect Immun 1990;58:2502-9.
8. Cairo MS, Mauss D, Kommareddy S, Norris K, Van de ven C, Modanlou H. Prophylactic and simultaneous administration of recombinant human granulocyte colony stimulating factor in the treatment of group B streptococcal sepsis in neonatal rats. Pediatric Res 1990;27:612-6.
9. Cairo MS, Plunkett JM, Mauss D, van de Ven C. Seven-day administration of recombinant human granulocyte colony-stimulating factor in newborn rats: modulation of neonatal neutrophilia, myelopoiesis, and group B sepsis. Blood 1990;76:1788-94.
10. Herbert JC, O'Reilly M, Gamelli RL. Protective effect of recombinant human granulocyte colony-stimulating factor against pneumococcal infections in splenectomized mice. Arch Surg 1990;125:1075-8.
11. Nelson S, Summer W, Bagby G, et al. Granulocyte colony-stimulating factor enhances pulmonary host defenses in normal and ethanol-treated rats. J Infect Dis 1991;164:901-6.
12. Chatta GS, Price TH, Allen RC, Dale DC. Effects of in vivo recombinant methionyl human granulocyte colony-stimulating factor on neutrophil response and peripheral blood colony-forming cells in healthy young and elderly adult volunteers. Blood 1994;84:2923-9.
13. Price TH, Chatta GS, Dale DC. The effect of recombinant granulocyte colony-stimulating factor on neutrophil kinetics in normal young and elderly humans. Blood 1996;88:335-40.
14. Allen RC, Stevens DL. The circulating phagocyte reflects the in vivo state of immune defense. Curr Opin Infect Dis 1992;5:389-98.
15. Allen RC. Role of oxygen in phagocyte microbicidal action. Environ Health Perspect 1994;102(suppl 10):201-8.
16. Wollen PS, Menconi MJ, Wang H, et al. Prior exposure to endotoxin exacerbates lipopolysaccharide-induced hypoxemia and alveolitis in anesthetized swine. Shock 1994;2:362-9.
17. Stevens DL, Bryant AE, Huffman J, Thompson K, Allen RC. Analysis of circulating phagocyte activity measured by whole blood luminescence: Correlation with clinical status. J Infect Dis 1994;170:1463-72.
18. Allen RC. Phagocytic leukocyte oxygenation activity and chemiluminescence: a kinetic approach to analysis. Methods Enzymol 1986;133:449-93.