Percutaneous absorption and skin erythema: Quantification of capsaicin and its synthetic derivatives from gels incorporated with benzalkonium chloride by using non-invasive bioengineering methods

Drug Development Research

Volumn 40, Issue 1, 1997, Pages 56-67

  Fang, Jia You ^a   Tsai, Ming Jun ^a   Huang, Yaw Bin ^a   Wu, Pao Chu ^a   Tsai, Yi Hung ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Benzalkonium chloride; Bioengineering method; Capsaicin; Percutaneous absorption

Indexed keywords

BENZALKONIUM CHLORIDE; CAPSAICIN; CAPSAICIN DERIVATIVE; CARBOPOL 940; NONIVAMIDE;

ADULT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; COLORIMETRY; CONTROLLED STUDY; DRUG SAFETY; DRUG TISSUE LEVEL; ERYTHEMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; IN VITRO STUDY; LASER DOPPLER FLOWMETRY; MALE; NONHUMAN; NORMAL HUMAN; SKIN ABSORPTION; SKIN BLOOD FLOW; SKIN IRRITATION; SKIN PERMEABILITY; SKIN WATER LOSS; SWINE; TOPICAL DRUG ADMINISTRATION;

EID: 0030990125     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199701)40:1<56::AID-DDR6>3.0.CO;2-S     Document Type: Article

References (46)

1. Agache DG, Dupond A (1994): Recent advances in non-invasive assessment of human skin blood flow. Acta Derm Venereol (Stockh) (Suppl) 185:47-51.
2. Agner T (1992): Noninvasive measuring methods for the investigation of irritant patch test reaction. Acta Derm Venereol (Stockh) (Suppl) 73:1-26.
3. Agner T, Serup J (1989): Skin reactions to irritants assessed by noninvasive bioengineering methods. Contact Dermatitis 20:352-359.
4. Agner T, Serup J (1990): Sodium laurylsulfate for irritant patch testing: A dose response study using bioengineering methods for determination of skin irritation. J Invest Dermatol 95:543-547.
5. Berardesea E, Maibach HI (1988): Bioengineering and the patch test. Contact Dermatitis 18:3-9.
6. Bircher A, DeBoer EM, Agner T, Wahlberg JE, Serup J (1994): Guidelines for measurement of cutaneous blood flow by laser Doppler flowmetry. Contact Dermatitis 30:65-72.
7. Bronaugh RL, Stewart RF (1986): Methods for in vitro percutaneous absorption studies 6: Preparation of the barrier layer. J Pharm Sci 75:487-491.
8. Buckley TL, Brain SD, Williams TJ (1990): Ruthenium red selectively inhibits oedema formation and increased blood (low induced by capsaicin in rabbit skin. Br J Pharmacol 99:7-8.
9. Catz P, Friend DR (1990): Transdermal delivery of levonorgestriol 8. Effect of enhancers on rat skin, hairless mouse skin, hairless guinea pig skin, and human skin. Int J Pharm 58:93-102.
10. Chan SY, Li Wan Po A (1992): Quantitative skin blanching assay for corticosteroid creams using tristimulus colour analysis. J Pharm Pharmacol 44:371-378.
11. Chen IJ, Yang JM, Yeh JL, Wu BN, Lo YC, Chen SJ (1992): Hypotensive and antinociceptive effects of ether-linked and relatively nonpungent analogues of N-nonanoyl vanillylamide. Eur J Med Chem 27:187-192.
12. Clozel JP, Roberts AM, Huffman JIE, Coleridge HM, Coleridge JCG (1985): Vagal chemoreflex coronary vasodilation evoked by stimulating pulmonary C-fibers in dogs. Circ Res 57:450-460.
13. Crimi N, Polosa R, Maccarrone C, Palermo B, Palermo F, Mistretta A (1992): Effect of topical application with capsaicin on skin responses to bradykinin and histamine in man. Clin Exp Allergy 22:933-939.
14. Dempski RE, De Marco JD, Markus AD (1965): An in vitro study of the relative moisture occlusive properties of several topical vehicles and saran wrap. J Invest Dermatol 44:361-363.
15. Fang JY, Tsai YH (1996a): Stability of nonivamide and sodium nonivamide acetate in solution at various pH values. Pharmazie 51:191-192.
16. Fang JY, Wu PC, Huang YB, Tsai YH (1995): In vitro permeation study of capsaicin and its synthetic derivatives from ointment bases using various skin types. Int J Pharm 126:119-128.
17. Fang JY, Wu PC, Huang YB, Tsai YH (1996b): Percutaneous absorption of capsaicin, nonivamide and sodium nonivamide acetate from gel and ointment bases: In vitro formulation evaluations in pigs and in vivo bioengineering methods in humans. Int J Pharm 130:121-135.
18. Glinski W, Glinska-Ferenz M, Pierozynska-Dubowska M (1991): Neurogenic inflammation induced by capsaicin in patients with psoriasis. Acta Derm Venereol (Stockh) 71:51-54.
19. Haves AG, Skingler M, Tyers MB (1981): Effects of single dose of capsaicin on nociceptive thresholds in the rodents. Neuropharmacology 20:505-511.
20. Hayes AG, Orford A, Reynolds M, Skingler AH, Skingler M, Smith C, Tyers MB (1984): The effects of a series of capsaicin analogues on nociception and body temperature in the rat. Life Sci 34:154-156.
21. Hoffmann K, Auer T, Stucker M, Dirschka T, el-Gammal S, Altmeyer P (1994): Evaluation of the efficacy of H1 blockers by noninvasive measurement techniques. Dermatology 189:146-151.
22. Hsu LR, Tsai YH, Huang YB (1991): The effect of pretreatment by penetration enhancers on the in vivo percutaneous absorption of piroxicam from its gel form in rabbits. Int J Pharm 71:193-200.
23. Imai S (1991): Effect of topically applied capsaicin on the cutaneous reaction to histamine. Arch Dermatol Res 283:414-416.
24. Kilo S, Schmelz M, Koltzenburg M, Handwerker HO (1994): Different patterns of hyperalgesia induced by experimental inflammation in human skin. Brain 117:385-396.
25. Lakmaker O, Pickering JW, van Gemert MJC (1993): Modeling the color perception of port wine stains and its relation to the depth of laser coagulated blood vessels. Lasers Surg Med 13:219-226.
26. La Motte RH, Lundberg LER, Torebjork HE (1992): Pain, hyperalgesia and activity in nociceptive-C units in humans after intradermal injection of capsaicin. J Physiol (Lond) 448:749-764.
27. Mathias T, Wilson DM, Maibach HI (1981): Transepidermal water loss as a function of skin surface temperature. J Invest Dermatol 77:219-220.
28. Neumann RA, Knobler RM, Lindmaier AP (1991): Photoelectric quantitative evaluation of argon laser treatment of port wine stains. Br J Dermatol 124:181-186.
29. Nose T, Tsurumi K (1993): Pharmacological studies on cutaneous inflammation induced by ultraviolet irradiation (1): Quantification of erythema by reflectance colorimetry and correlation with cutaneous blood flow. Jpn J Pharmacol 62:245-256.
30. Pierard GE, Pierard-Franchimont C (1993): Dihydroxyacetone test as a substitute for the dansyl chloride test. Dermatology 186:133-137.
31. Roberts RGD, Westerman RA, Widdop RE, Kotzmann RR, Payne R (1992): Effects of capsaicin on cutaneous vasodilator responses in humans. Agents Actions 37:53-59.
32. Schabauer AMA, Rooke TW (1994): Cutaneous laser Doppler flowmetry: Applications and findings. Mayo Clin Proc 69:564-574.
33. Serup J, Agner T (1990): Colorimetric quantification of erythema: A comparison of two colorimeters with a clinical scoring scheme and laser Doppler flowmetry. Clin Exp Dermatol 15:267-272.
34. Simone DA, Ochoa J (1991): Early and late effects of prolonged topical capsaicin on cutaneous sensibility and neurogenic inflammation induced by capsaicin in patients with psoriasis. Acta Derm Venereol (Stockh) 71:51-54.
35. Snater E, Janssen EAAJ, van der Valk PGM, van der Kerkhof PCM (1995): Transepidermal water vapour loss is not increased during and following dithranol irritation. Br J Dermatol 132:908-912.
36. Szocsanyi J, Jancso-Gaher A (1975): Sensory effects of capsaicin congeners part 1: Relationship between chemical structure and pain-producing potency of pungent agent. Arzneimittelforschung Drug Res 25:1877-1881.
37. Tominack RL, Spyker DA (1987): Capsicum and capsaicin. A review: Case report of the use of hot peppers in child abuse. Clin Toxicol 25:591-601.
38. Tsai YH, Hnang YB, Fang JY, Wu PC (1994): Percutaneous absorption of capsaicin and its derivatives. Drug Dev Ind Pharm 20:719-730.
39. van der Valk PGM, Kruis-de Vries MH, Nater JP, Bleumink E, de Jong MCJM (1985): Eczematous (irritant and allergic) reactions of the skin and barrier function as determined by water vapour loss. Clin Exp Dermatol 10:185-193.
40. Wang JP, Hsu MF, Teng CM (1984): Antiplatelet effect of capsaicin. Thromb Res 36:497-507.
41. Westerhof W, van Hasselt BAAM, Kammeijer A (1986): Quantification of UV-induced erythema with a portable computer controlled chromameter. Photodermatology 3:310-314.
42. Wilhelm KP, Surber C, Maibach HI (1989): Quantification of sodium laurylsulfate irritant dermatitis in man: Comparison of four techniques: Skin color refectance, transepidermal water loss, laser Doppler flow measurement and visual scores. Arch Dermatol Res 281:293-295.
43. Williams AC, Barry BW (1992): Skin absorption enhancers. Crit Rev Ther Drug Carrier Syst 9:305-353.
44. Wu PC, Fang JY, Huang YB, Tsai YH (1995): In vitro effect of penetration enhancers on sodium nonivainide acetate in rat skin. Biol Pharm Bull 18:1790-1792.
45. Yalkowsky SH, Zografi G (1972): Calculation of partial molal volume in micellar systems. J Pharm Sci 61:793-795.
46. Yang JM, Wu BN, Chen IJ (1992): Depressor response of sodium nonivamide acetate: A newly synthesized nonpungent analogue of capsaicin. Asia Pac J Pharmacol 7:95-102.