Significant reduction of human monocyte chemotactic response to monocyte-chemotactic protein 1 in patients with primary and metastatic malignant melanoma

Experimental Dermatology

Volumn 6, Issue 2, 1997, Pages 81-86

  Müller, Rembert ^a   Zheng, Min ^b   Mrowietz, Ulrich ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

chemotaxis; MCP 1; melanoma; monocyte; tumor

Indexed keywords

CHEMOTACTIC PEPTIDE;

ARTICLE; BASAL CELL CARCINOMA; CHEMOTAXIS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MELANOMA; METASTASIS; MONOCYTE; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, BASAL CELL; CHEMOKINE CCL2; CHEMOTAXIS; FEMALE; HUMANS; MALE; MELANOMA; MIDDLE AGED; MONOCYTES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEOPLASM METASTASIS; SKIN NEOPLASMS;

EID: 0030989936     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0625.1997.tb00151.x     Document Type: Article

References (19)

1. Garbe C, Büttner P, Bertz J et al. Dic Prognose des primären maligner Melanoms. Eine multizentrische Studie an 5093 Patienten. In: Orfanos CE, Garbe C, eds. Das maligne Melanom der Haut. München: Zuckschwerdt, 1990: 41-59.
2. Evans R. The immunological network at the site of tumor rejection. Biochim Biophys Acta 1986: 865: 1-11.
3. Mantovani A, Bottazzi B, Colotta F et al. The origin and function of tumor-associated macrophages. Immunol Today 1992: 13: 265-270.
4. Matsushima K, Larsen C G, Du Bois G et al. Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line. J Exp Med 1989: 169: 1485-1490.
5. Carr M W, Roth S J, Luther E et al. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc Natl Acad Sci USA 1994: 91: 3652-3656.
6. Graves D T, Barnhill R, Galanopoulos T et al. Expression of monocyte chemotactic protein-1 in human melanoma in vivo. Am J Pathol 1992: 140: 9-14.
7. Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Scand J Clin Lab Invest 1968: 21: 77-89.
8. Zheng M, Yang H, Mrowietz U. Isolation of human monocyte subpopulations by single-step counterflow centrifugation elutriation using a Sanderson chamber. Phenotypical and functional characterization of isolated cells. Clin Biotechnol 1991: 3: 197-201.
9. Mrowietz U, Jürgens G. A method for the determination of leukocyte migration for large sample numbers by automated densitometric quantification. J Biochem Biophys Methods 1995: 30: 49-58.
10. Poppema S, Bröcker E B, De Leij L et al. In situ analysis of the mononuclear cell infiltrate in primary malignant melanoma of the skin. Clin exp Immunol 1983: 51: 77-82.
11. Bröcker E B, Kolde G, Steinhausen D et al. The pattern of the mononuclear infiltrate as a prognostic parameter in flat superficial spreading melanomas. J Cancer Res Clin Oncol 1984: 107: 48-52.
12. Bröcker E B, Zwadlo G, Holzmann B et al. Inflammatory cell infiltrates in human melanoma at different stages of tumor progression. Int J Cancer 1988: 41: 562-567.
13. Mantovani A, Ming WJ, Balotta C et al. Origin and regulation of tumor-associated macrophages: the role of tumor-derived chemotactic factor. Biochim Biophys Acta 1986: 865: 59-67.
14. Snyderman R, Seigler H F, Meadows L. Abnormalities of monocyte chemotaxis in patients with melanoma: effects on immunotherapy and tumor removal. J Natl Cancer Inst 1977: 58: 37-41.
15. Norris D A, Huff J C, Swinehart J M et al. Cryoglobulinemia and decreased monocyte chemotaxis in malignant melanoma. J Invest Dermatol 1980: 75: 219-223.
16. Krasagakis K, Garbe C, Orfanos C E. Cytokines in human melanoma cells: synthesis, autocrine stimulation and regulatory functions - an overview. Melanoma Research 1993: 3: 425-433.
17. Armstrong C A, Tara D C, Hart C E et al. Heterogeneity of cytokine production by human malignant melanoma cells. Exp Dermatol 1992: 1: 37-45.
18. Mattei S, Colombo M P, Melani C et al. Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes. Int J Cancer 1994: 56: 853-857.
19. Zachariae C O C, Thestrup-Pedersen K, Matsushima K. Expression and secretion of leukocyte chemotactic cytokines by normal human melanocytes and melanoma cells. J Invest Dermatol 1991: 97: 593-599.