Studies on a new series of THA analogues: Effects of the aromatic residues that line the gorge of AChE

FEBS Letters

Volumn 409, Issue 2, 1997, Pages 155-160

  Pomponi, Massimo ^a   Marta, Maurizio ^a   Colella, Annalisa ^a   Sacchi, Silvia ^a   Patamia, Maria ^b   Gatta, Franco ^c   Capone, Francesca ^d   Oliverio, Alberto ^d   Pavone, Flaminia ^e  

^a CATHOLIC UNIVERSITY   (Italy)

^b CNR   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

^e Ist Psicobiologia Psicofarmacologia   (Italy)

Author keywords

Acetylcholinesterase catalysis; Acetylcholinesterase inhibitors; Acetylcholinesterase mechanism; Tacrine analogues

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; TACRINE DERIVATIVE;

ARTICLE; BINDING SITE; CATALYSIS; ENZYME INHIBITION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; ANIMALS; CHOLINESTERASE INHIBITORS; CRYSTALLOGRAPHY, X-RAY; ELECTROPHORUS; KINETICS; MODELS, MOLECULAR; PROTEIN CONFORMATION; TACRINE; TORPEDO;

ELECTROPHORUS ELECTRICUS;

EID: 0030989863     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00492-4     Document Type: Article

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