Glucose regulation of islet amyloid polypeptide gene expression in rat pancreatic islets

American Journal of Physiology - Endocrinology and Metabolism

Volumn 272, Issue 4 35-4, 1997, Pages

  Gasa, R ^a   Gomis, R ^a,b   Casamitjana, R ^a   Rivera, F ^a   Novials, A ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

Author keywords

amylin; glucose metabolism; insulin; messenger ribonucleic acid

Indexed keywords

AMYLIN; AMYLOID; DIAZOXIDE; MANNOHEPTULOSE; MESSENGER RNA; POLYPEPTIDE; VERAPAMIL;

ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; ENZYME REGULATION; GENE EXPRESSION REGULATION; GLUCOSE METABOLISM; GLYCOLYSIS; NONHUMAN; PANCREAS ISLET CELL; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROMOTER REGION; RAT; RNA ANALYSIS; SECOND MESSENGER; TRANSCRIPTION REGULATION;

EID: 0030989115     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1997.272.4.e543     Document Type: Article

References (33)

1. Alam, T., L. Chen, A. Ogawa, J. D. Leffert, R. H. Unger, and K. L. Luskey. Coordinate regulation of amylin and insulin expression in response to hypoglycemia and fasting. Diabetes 41: 508-514, 1992.
2. Bretherton-Watt, D., M. A. Gathei, S. R. Bloom, H. Jamal, G. J. Ferrier, S. I. Girgis, and S. Legon. Altered islet amyloid polypeptide (amylin) gene expression in rat models of diabetes. Diabetologia 32: 881-883, 1989.
3. Brunstedt, J., and S. J. Chan. Direct effect of glucose on preproinsulin mRNA levels in isolated pancreatic islets. Biochem. Biophys. Res. Commun. 106: 1383-1389, 1982.
4. Clark, A., C. A. Edwards, L. R. Ostle, R. Sutton, J. B. Rothbard, J. F. Morris, and R. C. Turner. Localisation of islet amyloid peptide in lipofucsin bodies and secretory granules of human B-cells and in islets of type 2 diabetic subjects. Cell Tissue Res. 257: 179-185, 1989.
5. Cooper, G. J. S., A. C. Willis, A. Clark, R. C. Turner, R. B. Sim, and K. B. Reid. Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc. Natl. Acad. Sci. USA 84: 8628-8632, 1987.
6. German, M. S., L. G. Moss, and W. J. Rutter. Regulation of insulin gene expression by glucose and calcium in transfected primary islet cultures. J. Biol. Chem. 265: 22063-22066, 1990.
7. German, M. S., L. G. Moss, J. H. Wang, and W. J. Rutter. The insulin and islet amyloid polypeptide genes contain similar cell-spcific promoter elements that bind identical beta-cell nuclear complexes. Mol. Cell. Biol. 12: 1777-1788, 1992.
8. Giddings, S. J., L. R. Carnaghi, and R. A. Shalwitz. Hypoglycemia but not hyperglycemia induces rapid changes in pancreatic beta-cell gene transcription. Am. J. Physiol. 265 (Endocrinol. Metab. 28): E259-E266, 1993.
9. Goodison, S., S. Kenna, and J. H. Ashcroft. Control of insulin gene expression by glucose. Biochem. J. 285: 563-568, 1992.
10. Hammonds, P., P. N. Schofield, and J. H. Ashcroft. Glucose regulates preproinsulin mRNA levels in a clonal cell line of simian virus 40-transformed β-cells. FEBS Lett. 213: 149-154, 1987.
11. Hammonds, P., P. N. Schoffield, S. J. H. Ashcroft, R. Sutton, and D. W. R. Gray. Regulation and specificity of glucose-stimulated insulin gene expression in human islets of Langerhans. FEBS Lett. 223: 131-137, 1987.
12. Johnson, K. H., T. D. O'Brien, D. W. Hayden, K. Jordon, H. K. J. Ghobrial, W. C. Mahoney, and P. Westermark. Immunolocalization of islet amyloid polypeptide (IAPP) in pancreatic beta cells by means of peroxidase-antiperoxidase (PAP) and protein-A-gold techniques. Am. J. Pathol. 130: 1-8, 1988.
13. Leighton, B., and G. J. S. Cooper. Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro. Nature 335: 632-635, 1988.
14. Leinweber, K. P., and H. Schatz. Long-term and short-term effects of calcium, verapamil and diazoxide on biosynthesis and release of (pro)insulin in isolated islets of rat pancreas. Acta Endocrinologica 99: 94-100, 1982.
15. Madsen, O., J. H. Nielsen, B. Michelsen, P. Westermark, C. Betsholtz, M. Nishi, and D. F. Steiner. Islet amyloid polypeptide and insulin expression are controlled differently in primary and transformed islet cells. Mol. Endocrinol. 5: 143-148, 1991.
16. McDonald, M. J., L. A. Fahien, D. I. McKenzie, and S. M. Moran. Novel effects of insulin secretagogues on capacitation of insulin release and survival of cultured pancreatic islets. Am. J. Physiol. 259 (Endocrinol. Metab. 22): E548-E554, 1990.
17. Melloul, D., and E. Cerasi. Transcription of the insulin gene: towards defining the glucose-sensitive elements and trans-acting factors Diabetologia 37, Suppl. 2: S3-S10, 1994.
18. Moore, C. X., and G. J. S. Cooper. Co-secretion of amylin and insulin from cultured islet β-cells: modulation by nutrient secretagogues, islet hormones and hypoglycemic islets. Biochem. Biophys. Res. Commun. 179: 1-9, 1991.
19. Mosselman, S., J. W. H. Höppener, L. de Wit, W. Soeller, C. J. M. Lips, and H. S. Jansz. IAPP/amylin gene transcriptional region. Evidence for negative regulation. FEBS Lett. 271: 33-36, 1990.
20. Mulder, H., B. Ahren, M. Stridsberg, and F. Sundler. Non-parallellism of islet amyloid polypeptide (amylin) and insulin expression in rat islets following dexamethasone treatment. Diabetologia 38: 395-402, 1995.
21. Nagamatsu, S., M. Nishi, and D. F. Steiner. Biosynthesis of islet amyloid polypeptide. Elevated expression in mouse βTC3 cells. J. Biol. Chem. 266: 13737-13741, 1991.
22. Nicholl, C. G., J. M. Bhatavdekar, J. Mak, S. I. Girgis, and S. Legon. Extra-pancreatic expression of the rat islet amyloid polypeptide (amylin) gene. J. Mol. Endocrinol. 9: 157-163, 1992.
23. Nielsen, D.A., M. Welsh, M. J. Casadaban, and D. F. Steiner. Control of gene expression in pancreatic β-cells and in an insulin-producing cell line RIN 5F cells. J. Biol. Chem. 260: 13585-13589, 1985.
24. Novials, A., Y. Sarri, R. Casamitjana, F. Rivera, and R. Gomis. Regulation of islet amyloid polypeptide in human pancreatic islets. Diabetes 42: 1514-1519, 1993.
25. Philippe, J. Structure, and pancreatic expression of the insulin and glucagon genes. Endocr. Rev. 12: 252-271, 1991.
26. Schuppin, G. T., and C. J. Rhodes. Specific co-ordinated regulation of PCS and PC2 gene expression with that of preproinsulin in insulin-producing βTC3 cells. Biochem. J. 313: 259-268, 1996.
27. Stridsberg, M., S. Sandler, and E. Wilander. Cosecretion of islet amyloid polypeptide (IAPP) and insulin from isolated rat pancreatic islets following stimulation and inhibition of beta-cell functions. Regul. Pept. 45: 363-370, 1993.
28. Vaulont, S., and A. Kahn. Transcriptional control of metabolic regulation genes by carbohydrates. FASEB J. 8: 28-35, 1994.
29. Welsh, M., D. A. Nielsen, A. J. MacKrell, and D. F. Nielsen. Control of insulin gene expression in pancreatic β cells and in an insulin-producing cell line, RIN-5F cells. J. Biol. Chem. 260: 13590-13594, 1985.
30. Welsh, M., N. Scherberg, R. Gilmore, and D. F. Steiner. Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal recognition particle-mediated translational arrest by glucose. Biochem. J. 235: 459-467, 1986.
31. 2+, and a phorbol ester. Biochem. Biophys. Acta 47: 299-303, 1988.
32. Westermark, P., C. Wenstedt, E. Wilander, and K. Sletten. A novel peptide in the calcitonin gene-related peptide family as an amyloid fibril protein in the endocrine pancreas. Biochem. Biophys. Res. Commun. 140: 827-831, 1986.
33. Young, D. A., R. O. Deems, R. W. Deacon, R. H. McIntosh, and J. E. Foley. Effects of amylin on glucose metabolism and glycogenolysis in vivo and in vitro. Am. J. Physiol. 259 (Endocrinol. Metab. 22): E457-E461, 1990.