A 4-week and a 26-week repeated oral toxicity studies of betotastine besilate in dogs

Pharmacometrics

Volumn 53, Issue 4-5, 1997, Pages 319-326

  Koguchi, Atsushi ^a   Kawai, Yoshiaki ^a   Ichiki, Tsutomu ^b   Ogata, Hidehiro ^b   Kuwasaki, Emiko ^b   Masunaga, Akihiko ^b  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^b Panapharm Laboratories Co Ltd   (Japan)

Author keywords

(dogs, p.o.); Betotastine besilate; Toxicity study

Indexed keywords

ANTIALLERGIC AGENT; BETOTASTINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOG; DOSE RESPONSE; DRUG STRUCTURE; EPITHELIUM HYPERPLASIA; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; SALIVATION; TOXICITY TESTING; UROTHELIUM; VOMITING;

EID: 0030988696     PISSN: 03008533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (2)

1. de Groot, A.P., Feron, V.J. and Immel, H.R. (1988): Induction of hyperplasia in the bladder epithelium of rats by a dietary excess of acid or base: implications for toxicity/ carcinogenicity testing, Fd. Chem. Toxic., 26(5), 425-434.
2. (1997): Betotastine besilate 26 53, 299-318.