Malaria in East Africa

Journal of Pharmacy and Pharmacology

Volumn 49, Issue SUPPL. 2, 1997, Pages 9-12

  Watkins, W M ^a,b   Marsh, K ^a,c  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ; CHLOROQUINE; FANSIDAR; HALOFANTRINE; MEFLOQUINE; PYRONARIDINE; QUININE;

AFRICA; ARTICLE; CAUSE OF DEATH; CLINICAL TRIAL; DISEASE SEVERITY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG COST; DRUG HALF LIFE; DRUG MECHANISM; EPIDEMIC; FEVER; HEALTH CARE COST; HOST PARASITE INTERACTION; HUMAN; INFECTION CONTROL; INTRAMUSCULAR DRUG ADMINISTRATION; MALAISE; MALARIA; MORBIDITY; MORTALITY; PARASITEMIA; PARENTERAL DRUG ADMINISTRATION; PREVALENCE;

EID: 0030988602     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1997.tb06153.x     Document Type: Article

References (19)

1. Arnold, K. (1994) Early treatment of malaria in the community using artemisinin - hope or hazard? Trans. R. Soc. Trop. Med. Hyg 88 (Suppl. 1): 47-49
2. Clarke, D., Odialla, H., Ouma, J., Kenny, V., MacCabe, R., Rapuoda, B., Watkins, W. M. (1996) A malariometric survey in Turkana District, Kenya: chemosensitivity of in-vivo Plasmodium falciparum infections and identity of the vector. Trans. R. Soc. Trop. Med. Hyg. 90: 302-304
3. English, M., Crawley, J., Waruiru, C., Mwangi, I., Amukoiye, E., Marsh, K. (1996) Cerebral malaria is not an homogenous clinical syndrome. 17th African Health Sciences Congress, Kenya Medical Research Institute, Nairobi, Kenya, 5-9th Feb. (abstract)
4. Foster, S. D. (1991) Pricing, distribution and use of antimalarial drugs. Bull. World Health Organisation 69: 349-363
5. Greenwood, B. M., Bradley, A. K., Greenwood, A. M., Byass, P., Jammeh, K., Marsh, K., Tulloch, S., Oldfield, F. J. S., Hayes, R. (1987) Mortality and morbidity from malaria among children in a rural area of the Gambia. Trans. R. Soc. Trop. Med. Hyg. 81: 478-486
6. Marsh, K., Forster, D., Waruini, C., Mwangi, I., Winstanley, M., Marsh, V., Newton, C., Winstanley, P. A., Warn, P., Peshu, N., Pasvol, G., Snow, R. W. (1995) Indicators of life-threatening malaria in African children. N. Engl. J. Med. 332: 1399-1404
7. Murphy, S. A., Watkins, W. M., Bray, P., Lowe, B., Winstanley, P. A., Marsh, K. (1995) Parasite viability during treatment of severe falciparum malaria: differential effects of artemether and quinine. Am. J. Trop. Med. Hyg. 53: 303-305
8. Murphy, S., English, M., Waruiru, C., Mwangi, I., Amukoye, E., Crawley, J., Newton, C., Winstanley, P. A., Peshu, N., Marsh, K. (1996) An open randomised trial of artemether versus quinine in the treatment of cerebral malaria in African children. Trans. R. Soc. Trop. Med. Hyg. 90: 298-302
9. Pavitt, N. (1989) Kenya: the first explorers. Aurum Press Ltd, London
10. Ringwald, P., Bickii, J., Basco, L. (1996) Randomised trial of pyronaridine versus chloroquine for acute uncomplicated falciparum malaria in Africa. Lancet 347: 24-28
11. Waller, D., Krishna, S., Crawley, J., Miller, K., Kosten, F., Chapman, D., ter Kuile, F. O., Craddock, C., Berry, C., Holloway, P. A. H., Brewster, D., Greenwood, B. M., White, N. J. (1995). Clinical features and outcome of severe malaria in Gambian children. Clin. Infect. Dis. 21: 577-587
12. Warrell, D. A. (1993) Treatment and prevention of malaria. In: Gilles, H. M., Warrell, D. A. (eds) Essential Malariology. 3rd edn, Edward Arnold, London, p. 183
13. Watkins, W. M., Mosobo, M. (1993) Treatment of Plasmodium falciparum malaria with pyrimethamine-sulfadoxine: selective pressure for resistance is a function of long elimination half life. Trans. R. Soc. Trop. Med. Hyg. 87: 75-78
14. Watkins, W. M., Woodrow, C., Marsh, K. (1993) Falciparum malaria: differential effects of antimalarial drugs on ex vivo parasite viability during the critical early phase of therapy. Am. J. Trop. Med. Hyg. 49: 106-112
15. White, N. J., Ho, M. (1992) The pathophysiology of malaria. Adv. Parasitol 31: 84-173
16. White, N. J., Krishna, S. (1989) Treatment of malaria: some considerations and limitations of the current methods of assessment. Trans. R. Soc. Trop. Med. Hyg. 83: 767-777
17. White, N. J., Chapman, D., Watt, G. (1992) The effect of multiplication and synchronicity on the vascular distribution of parasites in falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 86: 590-597
18. Winstanley, P. A., Watkins, W. M., Newton, C. R. J. C., Nevill, C., Mberu, E., Warn, P. A., Waruira, C. M., Mwangi, I. N., Warrell, D. A., Maesh, K. (1992) The disposition of oral and intramuscular pyrimethamine/sulfadoxine in Kenyan children with high parasitaemia but clinically non-severe falciparum malaria. Br. J. Clin. Pharmacol. 33: 143-148
19. World Health Organization, Division of Control of Tropical Diseases. (1990) Severe and complicated malaria. Second Edition. Trans. R. Soc. Trop. Med. Hyg. 84 (Suppl. 2): 1-65