Enhancement or inhibition of HIV-1 replication by intracellular expression of sense or antisense RNA targeted at different intermediates of reverse transcription

AIDS

Volumn 11, Issue 5, 1997, Pages 587-595

  Peng, Hairong ^a   Callison, Deborah E ^a   Li, Peng ^a   Burrell, Christopher J ^a,b  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Antisense RNA; Gene therapy; Retroviral vector; Reverse transcription

Indexed keywords

ANTIGEN P24; COMPLEMENTARY RNA; METHIONINE TRANSFER RNA; VIRUS DNA; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; EXPRESSION VECTOR; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LEUKEMIA CELL LINE; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RETROVIRUS; REVERSE TRANSCRIPTION; RNA SEQUENCE; T LYMPHOCYTE; VIRION; VIRUS REPLICATION;

CELL LINE; GENE EXPRESSION REGULATION, VIRAL; HIV-1; HUMANS; RNA, ANTISENSE; TRANSCRIPTION, GENETIC; TRANSFECTION; VIRUS REPLICATION;

EID: 0030988065     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199705000-00006     Document Type: Article

References (38)

1. Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, Markowitz M: Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 1995, 373:123-126.
2. Wei X, Ghosh SK, Taylor ME, et al.: Viral dynamics in human immunodeficiency virus type 1 infection. Nature 1995, 373:117-195.
3. Rhodes A, James W: Inhibition of human immunodeficiency virus replication in cell culture by endogenously synthesized antisense RNA. J Gen Virol 1990, 71:1965-1974.
4. Sczakiel G, Pawlita M: Inhibition of human immunodeficiency virus type 1 replication in human T cells stably expressing antisense RNA. J Virol 1991, 65:468-472.
5. Sczakiel G, Oppenlénder M, Rittner K, Pawlita M: Tat- and Rev-directed antisense RNA expression inhibits and abolishes replication of human immunodeficiency virus type 1: a temporal analysis. J Virol 1992, 66:5576-5581.
6. Chatterjee S, Johnson PR, Wong Jr KK: Dual-target inhibition of HIV-1 in vitro by means of an adeno-associated virus antisense vector. Science 1992, 258:1485-1488.
7. Joshi S, Brunschot AV, Asad S, Elst JVD, Read SE, Bernstein A: Inhibition of human immunodeficiency virus type 1 multiplication by antisense and sense RNA expression. J Virol 1991, 65:5524-5530.
8. Rhodes A, James W: Inhibition of heterologous strains of HIV by antisense RNA. AIDS 1991, 5:145-151.
9. Lee SW, Gallardo HF, Gilboa E, Smith C: Inhibition of human immunodeficiency virus type 1 in human 1 cells by a potent rev response element decoy consisting of the 13-nucleotide minimal rev-binding domain. J Virol 1994, 68:8254-8264.
10. Sullenger BA, Gallardo HF, Ungers GF, Gilboa E: Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation. J Virol 1991, 65:6811-6816.
11. Lisziewicz J, Sun D, Smythe J, et al.: Inhibition of human immunodeficiency virus type 1 replication by regulated expression of a polymeric tat activation response RNA decoy as a strategy for gene therapy in AIDS. Proc Natl Acad Sci USA 1993, 90:8000-8004.
12. Sarver N, Cantin EM, Chang PS, et al.: Ribozymes as potential anti-HIV-1 therapeutic agents. Science 1990, 247:1222-1225.
13. Dropic B, Lin NH, Martin MA, Jeang K-T: Functional characterization of a U5 ribozyme: intracellular suppression of human immunodeficiency virus type 1 expression. J Virol 1992, 66:1432-1441.
14. Lo KMS, Biasolo MA, Dehni G, Palú G, Haseltine W: Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA. Virology 1992, 190:176-183.
15. Ojwang JO, Hampel A, Looney DJ, Wong-Staal F, Rappaport J: Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme. Proc Natl Acad Sci USA 1992, 89:10802-10806.
16. Weerasinghe M, Liem SE, Asad S, Read SE, Joshi S: Resistance to human immunodeficiency virus type 1 (HIV-1) infection in human CD4+ lymphocyte-derived cell lines conferred by using retroviral vectors expressing an HIV-1 RNA-specific ribozyme. J Virol 1991, 65:5531-5534.
17. Yu M, Ojwang J, Yamada O, et al.: A hairpin ribozyme inhibits expression of diverse strains of human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1993, 90:6 340-6 344.
18. Yamada O, Yu M, Yee J-K, Kraus G, Looney D, Wong-Staal F: Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1. Gene Ther 1994, 1:38-45.
19. Sun LQ, Warrilow D, Wang L, Witherington G, Macpherson J, Symond G: Ribozyme-mediated suppression of Moloney murine leukemia virus and human immunodeficiency virus type 1 replication in permissive cell lines. Proc Natl Acad Sci USA 1994, 91:9715-9719.
20. Yu M, Leavitt MC, Maruyama M, et al.: Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1995, 92:699-703.
21. Panganiban AT, Fiore D: Ordered interstrand and intrastrand DNA transfer during reverse transcription. Science 1988, 241:1064-1069.
22. Hu W-S, Temin HM: Retroviral recombination and reverse transcription. Science 1990, 250:1227-1233.
23. Li P, Stephenson AJ, Kuiper LJ, Burrell CJ: Double-stranded strong-stop DNA and the second template switch in human immunodeficiency virus (HIV) DNA synthesis. Virology 1993, 194:82-88.
24. Jones JS, Allan RW, Temin HM: One retroviral RNA is sufficient for synthesis of viral DNA. J Virol 1994, 68:207-216.
25. Karageorgos L, Li P, Burrell CJ: Stepwise analysis of reverse transcription in a cell-to-cell human immunodeficiency virus infection model: kinetics and implications. J Gen Virol 1995, 76:1675-1686.
26. Kupiec J-J, Sonigo P: Reverse transcriptase jumps and gaps. J Gen Virol 1996, 77:1987-1991.
27. Hantzopoulos P, Sullenger BA, Ungers G, Gilsa E: Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector. Proc Nat Acad Sci USA 1989, 86:3519-3523.
28. Peng H, Callison D, Li C, Burrell C: Long term protection against HIV-1 infection conferred by tat or rev antisense RNA was affected by the design of retroviral vector. Virology 1996, 220:377-389.
29. Peng H, Reinhart TA, Retzel EF, Staskus KA, Zupancic M, Haase AT: Single cell transcript analysis of human immunodeficiency virus gene expression in the transition from latent to productive infection. Virology 1995, 206:16-27.
30. Sambrook J, Fritsch EF, Maniatis T (eds): Molecular Cloning: A Laboratory Manual. 2nd Edn. Cold Spring Harbor: Cold Spring Harbor Laboratory Press; 1989.
31. Miller AD, Buttimore C: Redesign of retrovirus packaging cell line to avoid recombination leading to helper virus production. Mol Cell Biol 1986, 6:2895-2902.
32. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidium thiocynate-phenol-chloroform extraction. Anal Biochem 1987, 162:156-159.
33. Gilman M: Preparation of cytoplasmic RNA from tissue culture cells. In Current Protocols in Molecular Biology. Edited by Ausubel FM, Brent R, Kington RE, et al. New York: John Wiley & Sons; 1992; 4.1.2-4.1.6.
34. Hirt B: Selective extraction of polyoma DNA from infected mouse cell culture. J Mol Biol 1967, 26:365-369.
35. Li P, Burrell CJ: Synthesis of human immunodeficiency virus DNA in a cell-to-cell transmission model. AIDS Res Hum Retrovirus 1992, 8:253-259.
36. Sattentau QJ, Dalgleish AG, Weiss RA, Beverley PCL: Epitopes of the CD4 antigen and HIV infection. Science 1986, 234:1120-1123.
37. Bauer HM, Yi T, Greer CE, et al.: Genital human papillomavirus infection in female university students as determined by PCR-based method. JAMA 1991, 265:472-477.
38. Parrott C, Seidner T, Duh E, et al.: Variable role of the long terminal repeat Sp1-binding sites in human immunodeficiency virus replication in T lymphocytes. J Virol 1991, 65:1414-1419.