1,25-Dihydroxyvitamin D3 induces the expression of vascular endothelial growth factor in osteoblastic cells

Endocrine Research

Volumn 23, Issue 3, 1997, Pages 213-229

  Schlaeppi, Jean Marc ^b   Gutzwiller, Sabine ^b   Finkenzeller, Günter ^a   Fournier, Brigitte ^b  

^a TUMOR BIOLOGY CENTER   (Germany)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; DEXAMETHASONE; PARATHYROID HORMONE[1-34]; VASCULOTROPIN; VITAMIN D RECEPTOR;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HORMONAL REGULATION; HUMAN; HUMAN CELL; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0030987617     PISSN: 07435800     EISSN: None     Source Type: Journal    
DOI: 10.3109/07435809709031855     Document Type: Article

References (38)

1. Folkman J, Shing Y. 1992 Angiogenesis. J Biol Chem 267:10931-10934.
2. Winet H. 1996 The role of microvasculature in normal and perturbed bone healing as revealed by intravital microscopy. Bone 19:39S-57S.
3. Trueta J, Amato VP. 1960 The vascular contribution to osteogenesis. III. Changes in the growth cartilage caused by experimentally induced ischaemia. J Bone Joint Surg 42B:571-587.
4. Brighton CT. 1978 Structure and function of the growth plate. Clin Orthop Rel Res 136:22-32.
5. Burkhardt R, Kettner G, Böhm W, Schmidmeier M, Schlag R, Frisch B, Mallmann B, Eisenmenger W, Gilg TH. 1987 Changes in trabecular bone, hematopoiesis and bone marrow vessels in aplastic anemia, primary osteoporosis, and old age: a comparative histomorphometric study. Bone 8:157-164.
6. Hunter WL, Arsenault L, Hodsman AB. 1991 Rearrangement of the metaphyseal vasculature of the rat growth plate in rickets and rachitic reversal: a model of vascular arrest and angiogenesis renewed. Anat Rec 229:453-461.
7. Streeten EA, Brandi ML. 1990 Biology of bone endothelial cells. Bone Miner 10:85-94.
8. Guenther HL, Fleisch H, Sorgente N. 1986 Endothelial cells in culture synthesize a potent bone cell active mitogen. Endocrinology 119:193-201.
9. Dvorak HF, Brown LF, Detmar M, Dvorak AM. 1995 Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 146:1029-1039.
10. Ferrara N, Houck K, Jakeman L, Leung DW. 1992 Molecular and biological properties of the vascular endothelial growth factor family of proteins. Endocrine Rev 13:18-32.
11. Ferrara N. 1995 The role of vascular endothelial growth factor in pathological angiogenesis. Breast Cancer Res Treat 36:127-137.
12. 1 in osteoblasts. J Clin Invest 93:2490-2496.
13. Goad DL, Rubin J, Wang H, Tashjian Jr AH, Patterson C. 1996 Enhanced expression of vascular endothelial growth factor in human SaOS-2 osteoblast-like cells and murine osteoblasts induced by insulin-like growth factor I. Endocrinology 137:2262-2268.
14. 3 in human osteoblast-like cells. J Bone Miner Res 11:472-479.
15. Tischer E, Mitchell R, Hartman T, Silva M, Gospodarowicz D, Fiddes JC, Abraham JA. 1991 The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem 266:11947-11954.
16. Houck KA, Leung DW, Rowland AM, Winer J, Ferrara N. 1992 Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J Biol Chem 267:26031-26037.
17. De Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT. 1992 The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255:989-991.
18. Terman BI, Dougher-Vermazen M, Carrion ME, Dimitrov D, Armellino DC, Gospodarowicz D, Böhlen P. 1992 Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 187:1579-1586.
19. Kolch W, Martiny-Baron G, Kieser A, Marmé D. 1995 Regulation of the expression of the VEGF/VPS and its receptors: role in tumor angiogenesis. Breast Cancer Res Treat 36:139-155.
20. Rak J, Filmus J, Finkenzeller G, Grugel S, Marmé D, Kerbel RS. 1995 Oncogenes as inducers of tumor angiogenesis. Cancer Metastasis Rev 14:263-277.
21. Cullinan-Bove K, Koos RD. 1993 Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth. Endocrinology 133:829-837.
22. Shweiki D, Itin A, Neufeld G, Gitay-Goren H, Keshet E. 1993 Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. J Clin Invest 91:2235-2243.
23. Fiebich BL, Jäger B, Schöllmann C, Weindel K, Wilting J, Kochs G, Marmé D, Hug H, Weich HA. 1993 Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells. Eur J Biochem 211:19-26.
24. Finkenzeller G, Technau A, Marmé D. 1995 Hypoxia-induced transcription of the vascular endothelial growth-factor gene is independent of functional AP-1 transcription factor. Biochem Biophys Res Commun 208:432-439.
25. Rodan SB, Imai Y, Thiede MA, Wesolowski G, Thompson D, Bar-Shavit Z, Shull S, Mann K, Rodan GA. 1987 Characterization of a human osteosarcoma cell line (Saos-2) with osteoblastic properties. Cancer Res 47:4961-4966.
26. Fournier B, Price PA. 1991 Characterization of a new human osteosarcoma cell line OHS-4. J Cell Biol 114:577-583.
27. Schlaeppi J-M, Eppenberger U, Martiny-Baron G, Küng W. 1996 Chemiluminescence immunoassay for vascular endothelial growth factor (vascular permeability factor) in tumor-tissue homogenates. Clin Chem 42:1777-1784.
28. 3 receptor in mouse fibroblasts. Biochem Biophys Res Commun 131:378-385.
29. Rao LG, Wylie JN, Kung Sutherland MS, Murray TM. 1994 17 β-estradiol and parathyroid hormone potentiate each other's stimulatory effects on alkaline phosphatase activity in SaOS-2 cells in a differentiation-dependent manner. Endocrinology 134:614-620.
30. 3 receptor levels and augments bioresponses in rat osteoblast-like cells. Endocrinology 118:1119-1126.
31. Reichel H, Koeffler HP, Norman AW. 1989 The role of the vitamin D endocrine system in health and disease. N Engl J Med 320:980-991.
32. Ross TK, Darwish HM, Deluca HF. 1994 Molecular biology of vitamin D action. Vitam Horm 49:281-326.
33. 3. Interplay with retinoid and thyroid hormone signalling. Eur J Biochem 231:517-527.
34. Haussler MR, Jurutka PW, Hsieh J-C, Thompson PD, Selznick SH, Haussler CA, Whitfield GK. 1995 New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone. Bone 17:33S-38S.
35. Jonat C, Rahmsdorf HJ, Park K-K, Cato ACB, Gebel S, Ponta H, Herrlich P. 1990 Antitumor promotion and antiinflammation down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell 62:1189-1204.
36. Schüle R, Rangarajan P, Kliewer S, Ransone LJ, Bolado J, Yang N, Verma IM, Evans RM. 1990 Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell 62:1217-1226.
37. 3 receptors by parathyroid hormone in osteoblastic cells: role of second messenger pathways. Endocrinology 136:705-712.
38. Fujimori A, Cheng S-L, Avioli LV, Civitelli R. 1992 Structure-function relationship of parathyroid hormone: activation of phospholipase-C, protein kinase-A and -C in osteosarcoma cells. Endocrinology 130:29-36.