Detection and structural characterization of ras oncoprotein-inhibitors complexes by electrospray mass spectrometry

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 5, 1997, Pages 817-820

  Ganguly, A K ^a   Pramanik, B N ^a   Huang, E C ^a   Liberles, S ^a,b   Heimark, L ^a   Liu, Y H ^a   Tsarbopoulos, A ^a   Doll, R J ^a   Taveras, A G ^a   Remiszewski, S ^a   Snow, M E ^a   Wang, Y S ^a   Vibulbhan, B ^a   Cesarz, D ^a   Brown, J E ^a   Del Rosario, J ^a   James, L ^a   Kirschmeier, P ^a   Girijavallabhan, V ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE DIPHOSPHATE; PROTEIN INHIBITOR; RAS PROTEIN; SCH 54292; SCH 54341; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; COMPLEX FORMATION; IONIZATION; MASS SPECTROMETRY; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE MAPPING;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BINDING SITES; DRUG EVALUATION, PRECLINICAL; GLUCOSIDES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; MACROMOLECULAR SUBSTANCES; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PEPTIDE MAPPING; PROTEINS; RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RAS PROTEINS; SULFONAMIDES;

EID: 0030987442     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00021-7     Document Type: Article

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