Neuroleptic binding to sigma receptors: Possible involvement in neuroleptic-induced acute dystonia

Biological Psychiatry

Volumn 41, Issue 10, 1997, Pages 1010-1019

  Jeanjean, Anne P ^a   Laterre, E Christian ^a   Maloteaux, Jean Marie ^a  

^a CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

receptors; acute dystonia; cholinergic muscarinic receptors; dopaminergic D2 receptors; neuroleptic antipsychotic

Indexed keywords

AMISULPRIDE; BENPERIDOL; BROMPERIDOL; BUSPIRONE; BUTACLAMOL; CHLORPROMAZINE; CLOZAPINE; DOMPERIDONE; DOPAMINE 2 RECEPTOR; DROPERIDOL; FLUPENTIXOL; FLUPHENAZINE; HALOPERIDOL; LOXAPINE; METOCLOPRAMIDE; MUSCARINIC RECEPTOR; NEUROLEPTIC AGENT; PENFLURIDOL; PIMOZIDE; PIPAMPERONE; PIPOTIAZINE; SIGMA OPIATE RECEPTOR; SULPIRIDE; THIOPROPERAZINE; THIORIDAZINE; TIOTIXENE; TRIFLUOPERAZINE; TRIFLUPERIDOL; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DYSTONIA; HUMAN; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIPSYCHOTIC AGENTS; DOPAMINE AGONISTS; DYSKINESIA, DRUG-INDUCED; MALE; PIPERIDINES; QUINUCLIDINYL BENZILATE; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; RECEPTORS, MUSCARINIC; RECEPTORS, SIGMA; SPIPERONE;

EID: 0030987435     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(96)00264-8     Document Type: Article

References (75)

1. Addonizio G, Alexopoulos GS (1988): Drug-induced dystonia in young and elderly patients. Am J Psychiatry 145:169-171.
2. Arrowsmith J, Gamse RA (1981): Dystonia with droperidol therapy (letter). N Engl J Med 305:227.
3. Ayd FJ (1961): A survey of drug-induced extrapyramidal reactions. JAMA 175:1054-1060.
4. Bateman DN, Rawlins M, Simpson JM (1985): Extrapyramidal reactions with metoclopramide. Br Med J Clin Res 291:930-932.
5. Black JL, Richelson E, Richardson JW (1985): Antipsychotic agents: A clinical update. Mayo Clin Proc 60:777-789.
6. Borison RL, Diamond BI, Dren AT (1991): Does sigma receptor antagonism predict clinical antipsychotic efficacy? Psychopharmacol Bull 27:103-106.
7. Boyer WE, Bakalar NH, Lake CR (1987): Anticholinergic prophylaxis of acute haloperidol-induced acute dystonic reactions. J Clin Psychopharmacol 7:164-166.
8. Boylan K (1990): Persistent dystonia associated with buspirone. Neurology 40:1904.
9. Casey DE (1994): Motor and mental aspects of acute extrapyramidal syndromes. Acta Psychiatr Scand 89(suppl 380): 14-20.
10. Cerosimo RJ, Bromer R, Hoffer S, Welch J, Abrahamson M, Hong WK (1985): The antiemetic activity of droperidol administered by intramuscular injection during cisplatin chemotherapy: A pilot study. Drug Intell Clin Pharmacol 19: 118-121.
11. Chakos MH, Mayerhoff DI, Loebel AD, Alvir JM, Lieberman JA (1992): Incidence and correlates of acute extrapyramidal symptoms in first episode of schizophrenia. Psychopharmacol Bull 28:81-86.
12. Creese I, Burt DR, Snyder SH (1976): Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 75:133-140.
13. Deutsch SI, Weizman A, Goldman ME, Morihisa JM (1988): The sigma receptor: A novel site implicated in psychosis and antipsychotic drug efficacy. Clin Neuropharmacol 11:105-119.
14. Dubin WR, Weiss KJ (1986): Rapid tranquilization: A comparison of thiothixene with loxapine. J Clin Psychiatry 47:294-297.
15. Edge SB, Funkhouser WK, Berman A, et al (1987): High-dose oral and intravenous metoclopramide in doxorubicin/cyclophosphamide-induced emesis. A randomized double-blind study. Am J Clin Oncol 10:257-263.
16. Ernst M, Gonzalez NM, Campbell M (1993): Acute dystonic reaction with low-dose pimozide. J Am Acad Child Adolesc Psychiatry 32:640-642.
17. Findlay M, Simes RJ, Cox K, et al (1993): A randomised cross-over trial of antiemetic therapy for platinum-based chemotherapy. Improved control with an intensive multiagent regimen. Eur J Cancer 29A:309-315.
18. Freedman DX (1973): Neurological syndromes associated with antipsychotic drug use. Arch Gen Psychiatry 28:463-467.
19. Furlanut M, Benetello P, Perosa A, Colombo G, Gallo F, Forgione A (1988): Pharmacokinetics of benperidol in volunteers after oral administration. Int J Clin Pharmacol Res 8:13-16.
20. Gandara DR (1991): Progress in the control of acute and delayed emesis induced by cisplatin. Eur J Cancer 27(suppl 1):S9-S11.
21. Gillis A (1969): Acute phenothiazine dystonia. Lancet ii:1299-1300.
22. Goff DC, Arana GW, Greenblatt DJ, et al (1991): The effect of benztropine on haloperidol-induced dystonia, clinical efficacy and pharmacokinetics: A prospective, double-blind trial. J Clin Psychopharmacol 11:106-112.
23. Groves JE, Mandel MR (1975): The long-acting phenothiazines. Arch Gen Psychiatry 32:893-900.
24. 3H]3-(3-hydroxyphenyl)-N(1-propyl)piperidine. J Neurosci 6:1757-1770.
25. Hainsworth J, Harvey W, Pendergrass K, et al (1991): A single-blind comparison of intravenous ondnsetron, a selective serotonin antagonist, with intravenous metoclopramide in the prevention of nausea and vomiting associated with high-dose cisplatin chemotherapy. J Clin Oncol 9:721-728.
26. Howrie DL, Felix C, Wollman M, Juhl RP, Blatt J (1986): Metoclopramide as an antiemetic agent in pediatric oncology patients. Drug Intell Clin Pharmacol 20:122-124.
27. Hyams JS, Leichtner AM, Zamett LO, Walters JK (1986): Effects of metoclopramide on prolonged intraesophageal pH testing in infants with gastroesophageal reflux. J Pediatr Gastroenterol Nutr 5:716-720.
28. Itoh H (1985): A comparison of the clinical effects of bromperidol, a new butyrophenone derivative, and haloperidol on schizophrenia using a double-blind technique. Psychopharmacol Bull 21:120-122.
29. Jankovic J, Patel SC (1983): Blepharospasm associated with brainstem lesions. Neurology 33:1237-1240.
30. Jansen KLR (1991): Buspirone and dystonia. Neurology 41: 1850.
31. Jansen KLR, Faull RLM, Dragunow M, Leslie RA (1991): Autoradiographic distribution of sigma receptors in human neocortex, hippocampus, basal ganglia, cerebellum, pineal and pituitary glands. Brain Res 559:172-177.
32. Kastrup O, Caspar M, Schwarz M (1992): Acute dystonia due to clozapine [letter]. J Neural Neurosurg Psychiatry 57:119.
33. Klein M, Cooper TB, Musacchio JM (1994): Effects of haloperidol and reduced haloperidol on binding to sigma sites. Eur J Pharmacol 254:239-248.
34. Korpi ER, Kleinman JE, Costakos DT, Linnoila M, Wyatt RJ (1983): Reduced haloperidol in the postmortem brains of haloperidol treated patients. Psychiatry Res 11:259-269.
35. Lahti LA, Evans DL, Stratman NC, Figur LM (1993): Dopamine D4 versus D2 receptor selectivity of dopamine receptor antagonists: Possible therapeutic implications. Eur J Pharmacol 236:483-486.
36. Lapierre YD (1978): A controlled study of penfluridol in the treatment of chronic schizophrenia. Am J Psychiatry 35:956-959.
37. 3H]-3-(3hydroxyphenyl)-N-(1-propyl)piperidine. Proc Natl Acad Sci USA 81:4983-4987.
38. Linazasoro G, Marti-Masso JF, Olasagasti B (1991): Acute dystonia induced by sulpiride. Clin Neuropharmacol 14:463-464.
39. Lowry OH, Rosenbrough NJ, Fair AL, Randall RJ (1951): Protein measurements with the Folin phenol reagent. J Biol Chem 193:265.
40. Magliozzi JR, Gillespie H, Lombrozo L, Hollister LE (1985): Mood alteration following oral and intravenous haloperidol and relationship to drug concentration in normal subjects. J Clin Pharmacol 25:285-290.
41. Mann K, Bartels M, Bauer H, Gaertner HJ (1984): Amisulpride: An open clinical study of a new benzamide in schizophrenic patients. Pharmacopsychiatry 17:111-115.
42. Marshall G, Kerr S, Vowels M, O'Gorman-Hugues D, While L (1989): Antiemetic therapy for chemotherapy-induced vomiting: Metoclopramide, benztropine, dexamethasone, and lorazepam regimen compared with chlorpromazine alone. J Pediatr 115:156-160.
43. Martin WR, Eades Cg, Thompson JA, Huppler RE, Gilbert PE (1976): The effects of morphine-and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog. J Pharmacol Exp Ther 197:517-532.
44. Marty M, Pouillart P, Scholl S, et al (1990): Comparison of the 5-hydroxytryptamine3 (serotonin) antagonist ondansetron (GR38032F) with high-dose metoclopramide in the control of cisplatin-induced emesis. N Engl J Med 322:816-821.
45. Mash DC, Zabetian CP (1992): Sigma receptors are associated with cortical limbic areas in the primate brain. Synapse 12:195-205.
46. Matsumoto RR, Walker JM (1988): Inhibition of rubral neurons by a specific ligand for sigma receptors. Eur J Pharmacol 158:161-165.
47. Matsuno K, Matsunaga K, Senda T, Mita S (1993): Increase in extracellular acetylcholine level by sigma ligands in rat frontal cortex. J Pharmacol Exp Ther 265:851-859.
48. Migdalof BH, Grindel JM, Heykants JJ, Janssen PA (1979): Penfluridol: A neuroleptic drug designed for long duration of action. Drug Metab Rev 9:281-299.
49. Moleman P, Schmitz PJM, Ladee GA (1982): Extrapyramidal side effects and oral haloperidol: An analysis of explanatory patient and treatment characteristics. J Clin Psychiatry 43: 492-496.
50. Patrick SL, Walker JM, Perkel JM, Lockwood M, Patrick RL (1993): Increases in rat striatal extracellular dopamine and vacuous chewing produced by two sigma receptor ligands. Ear J Pharmacol 231:243-249.
51. Peatfield RC, Spokes EG (1984): Phenothiazine-induced dystonias [letter]. Neurology 34:260.
52. Pinder RM, Brogden RN, Swayer R, Speight TM, Spencer R, Avery GS (1976): Pimozide: A review of its pharmacological properties and therapeutic uses in psychiatry. Drugs 12:1-40.
53. Quirion R, Bowen WD, Itzhak Y, Julien JL, Musacchio JM, Bothman RB, Su TP, Tarn SW, Taylor DP (1992): A proposal for the classification of sigma binding sites. Trends Pharmacol Sci 13:85-86.
54. Relling MV, Mulhern RK, Fairclough D, Baker D, Pui CH (1993): Chlorpromazine with and without lorazepam as antiemetic therapy in receiving uniform chemotherapy. J Pediatr 123:811-816.
55. Remington GJ, Voineskos G, Pollock B, Reed K, Coulter K (1990): Prevalence of neuroleptic-induced dystonia in mania and schizophrenia. Am J Psychiatry 147:1231-1233.
56. Richelson E (1984): Neuroleptic affinities for human brain receptors and their use in predicting adverse effects. J Clin Psychiatry 45:331-336.
57. Ritchie EC, Bridenbaugh RH, Jabbari B (1988): Acute generalized myoclonus following buspirone administration. J Clin Psychiatry 49:242-243.
58. Rupniak NMJ, Jenner P, Marsden CD (1986): Acute dystonia induced by neuroleptic drugs. Psychopharmacology 88:403-419.
59. Schmidt K (1986): Pipothiazine palmitate: A versatile, sustained-action neuroleptic in psychiatric practice. Curr Med Res Opin 10:326-329.
60. Seeman P, Lee T, Chau-Wong M, Wong K (1976): Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 261:717-719.
61. Sigwald J, Bouttier D, Raymondeaud C, Piot C (1959): Quatre cas de dyskinésie facio-bucco-linguo-masticatrice à évolution prolongée secondaire à un traitement par les neuroleptiques. Rev Neurol 100:751-755.
62. Snyder SH, Largent BL (1989): Receptor mechanisms in antipsychotic drug action: Focus on sigma receptors. J Neuropsychiatry 1:7.
63. Sorbe B, Hallen C (1988): Betamethasone-dixyrazine versus metoclopramide as antiemetic treatment in cancer chemotherapy. Acta Oncol 27:357-360.
64. Sramek JJ, Simpson G, Morrison RL, Heiser JF (1986): Anticholinergic agents for prophylaxis of neuroleptic-induced dystonic reactions. A prospective study. J Clin Psychiatry 47:305-309.
65. Swett C (1975): Drug induced dystonia. Am J Psychiatry 132:532-534.
66. 3H]haloperidol binding in guinea pig brain membranes. Proc Natl Acad Sci USA 81:5618-5621.
67. Tarsy D (1983): Neuroleptic-induced extrapyramidal reactions: Classification, description and diagnosis. Clin Neuropharmacol 6:S9-S26.
68. Toru M, Moriya H, Yamamoto K, Shimazono Y (1976): A double-blind comparison of sulpiride with chlordiazepoxide in neurosis. Folia Psychiatr Neural Jpn 30:153-164.
69. Tuason VB (1986): A comparison of parenteral loxapine and haloperidol in hostile and aggressive acutely schizophrenic patients. J Clin Psychiatry 47:126-129.
70. Turk J, Lask B (1991): Pisa syndrome in an adolescent on neuroleptic medication. Br J Psychiatry 158:422-423.
71. Walker JM, Matsumoto RR. Bowen WD, Gans DL, Jones KD, Walker FO (1988): Evidence for a role of haloperidol-sensitive sigma-"opiate" receptors in the motor effects of antipsychotic drugs. Neurology 38:961-965.
72. Walker FO, Walker JM, Matsumoto RR, Bowen WD (1990a): Torticollis, midbrain and sigma receptors [letter]. Mov Disord 5:265.
73. Walker JM, Bowen WD, Walker FO, Matsumoto RR, deCosta BR, Rice KC (1990b): Sigma receptors: Biology and function. Pharmacol Rev 42:355-402.
74. Ward DF, Peters FC (1988): Unusual reaction to trifluoperazine. Postgrad Med 84:99-102.
75. Weissman AD, Casanova MF, Kleinman JE, London ED, deSouza EB (1991): Selective loss of cerebral cortical sigma but not PCP binding sites in schizophrenia. Biol Psychiatry 29:41-54.