The role of GH receptor tyrosine phosphorylation in Stat5 activation

Journal of Molecular Endocrinology

Volumn 18, Issue 3, 1997, Pages 213-221

  Hansen, J A ^a   Hansen, L H ^a   Wang, X ^b   Kopchick, J J ^b   Gouilleux, F ^c   Groner, B ^c   Nielsen, J H ^a   Moldrup A ^a   Galsgaard, E D ^a   Billestrup, N ^a  

^a HAGEDORN RESEARCH INSTITUTE   (Denmark)

^b OHIO UNIVERSITY   (United States)

^c TUMOR BIOLOGY CENTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE RECEPTOR; PROTEIN TYROSINE KINASE; STAT5 PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 0030986728     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0180213     Document Type: Article

References (26)

1. Allevato G, Billestrup N, Goujon L, Petersen ED, Norstedt G, Postel-Vinay M-C, Kelly PA & Nielsen JH 1995 Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation. Journal of Biological Chemistry 270 17210-17214.
2. Argetsinger LS, Campbell GS, Wang X, Witthuhn BA, Silvennoinen O, Ihle JN & Carter-Su C 1993 Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase. Cell 74 237-244.
3. 2+ oscillations and gene-transcription. Proceedings of the National Academy of Sciences of the USA 92 2725-2729.
4. Campbell GS, Pang L, Miyasaka T, Saltiel AR & Carter-Su C 1992 Stimulation by growth hormone of MAP kinase activity in 3T3-F442A fibroblasts. Journal of Biological Chemistry 267 6074-6080.
5. Campbell GS, Meyer DJ, Raz R, Levy DE, Schwartz J & Carter-Su C 1995 Activation of acute phase response factor (APRF)/stat3 transcription factor by growth hormone. Journal of Biological Chemistry 270 3974-3979.
6. Carter-Su C, Stubbart JR, Wang X, Stred SE, Argetsinger LS & Shafer JA 1989 Phosphorylation of highly purified growth hormone receptors by a growth hormone receptor-associated tyrosine kinase. Journal of Biological Chemistry 264 18654-18661.
7. Gouilleux F, Pallard C, Dusanter-Fourt I, Wakao H, Haldosen L-A, Norstedt G, Levy & Groner B 1995 Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity. EMBO Journal 14 2005-2013.
8. Goujon L, Allevato G, Simonin G, Paquereau L, LeCam A, Clarks J, Nielsen JH, Djiane J-M, Postel-Vinay M-C, Edery M & Kelly PA 1994 Cytoplasmic sequences of growth hormone receptor necessary for signal transduction. Proceedings of the National Academy of Sciences of the USA 91 957-961.
9. Hansen LH, Wang X, Kopchick JJ, Bouchelouche P, Nielsen JH, Galsgaard ED & Billestrup N 1996 Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and stat5 activation. Journal of Biological Chemistry 271 12669-12673.
10. Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M & McKnight SL 1994 An interleukin-4-induced transcription factor: IL-4 Stat. Journal of Biological Chemistry 265 1701-1706.
11. Hondo MM, DeMeyts P & Bouchelouche P 1994 Human growth hormone increases cytosolic free calcium in cultured human IM-9 lymphocytes: a novel mechanism of growth hormone transmembrane signalling. Biochemical and Biophysical Research Communications 202 391-397.
12. Kelly PA, Djiane J, Postel-Vinay M-C & Edery M 1991 The prolactin/growth hormone receptor family. Endocrine Reviews 12 235-251.
13. Lobie PE, Allevato G, Nielsen JH, Norstedt G & Billestrup N 1995 Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function. Journal of Biological Chemistry 270 21745-21750.
14. Mathews LS, Enberg B & Norstedt G 1989 Regulation of rat growth hormone receptor gene expression. Journal of Biological Chemistry 264 9905-9910.
15. Møldrup A, Allevato G, Dyrberg T, Nielsen JH & Billestrup N 1991 Growth hormone action in rat insulinoma cells expressing truncated growth hormone receptors. Journal of Biological Chemistry 266 17441-17445.
16. Moller C, Hansson A, Enberg B, Lobie PE & Norstedt G 1992 Growth hormone induction of tyrosine phosphorylation and activation of mitogen activated protein kinases in cells transfected with rat GH receptor cDNA. Journal of Biological Chemistry 267 23403-23408.
17. Ram PA, Park S, Choi HK & Waxman DJ 1996 Growth hormone activation of Stat 1, Stat 3 and Stat 5 in rat liver. Journal of Biological Chemistry 271 5929-5940.
18. Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, Neel BG, Birge RB, Fajardo JE, Chou M, Hanafusa H, Schaffhausen B & Cantley LC 1993 SH2 domains recognize specific phosphopeptide sequences. Cell 72 767-778.
19. Stahl N, Farruggella TJ, Boulton TG, Zhong Z, Darnell JE & Yancopoulos GD 1995 Choice of STAT's and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science 267 1349-1353.
20. VanderKuur J A, Wang X, Zhang L, Campbell GS, Allevato G, Billestrup N, Norstedt G & Carter-Su C 1994 Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase. Journal of Biological Chemistry 269 21709-21717.
21. VanderKuur J, Billestrup N, Allevato A, Norstedt G & Carter-Su C 1995a Growth hormone promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb-2. Journal of BiologicalChemistry 270 7587-7593.
22. VanderKuur J, Wang X, Zhang L, Allevato G, Billestrup N & Carter-Su C 1995b GH dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor. Journal of Biological Chemistry 270 21738-21744.
23. Wang X, Souza SC, Kelder B, Cioffi JA & Kopchick JJ 1995a A 40-amino acid segment of the growth hormone receptor cytoplasmic domain is essential for GH induced tyrosine phosphorylated cytosolic proteins. Journal of Biological Chemistry 270 6261-6266.
24. Wang X, Darus CJ, Xu BC & Kopchick JJ 1996 Identification of growth hormone receptor (GHR) tyrosine residues required for GHR phosphorylarion and JAK2 and STAT5 activation. Molecular Endocrinology 10 1249-1260.
25. Wang Y-D, Wong K & Wood WI 1995b Intracellular tyrosine residues of the human growth hormone receptor are not required for the signaling of proliferation or jak-stat activation. Journal of Biological Chemistry 270 7021-7024.
26. Yi W, Kim SO, Jiang J, Park SH, Kraft AS, Waxman DJ & Frank SJ 1996 Growth hormone receptor cytoplasmic domain differentially promotes stat3 and stat5b tyrosine phosphorylation by jak2 kinase. 10th International Congress of Endocrinology, San Francisco, 12-15 June.