Pharmacokinetics of sertindole and dehydrosertindole in volunteers with normal or impaired renal function

European Journal of Clinical Pharmacology

Volumn 52, Issue 3, 1997, Pages 223-227

  Wong, S L ^a   Menacherry, S ^a   Mulford, D ^a   Schmitz, P J ^a   Locke, C ^a   Granneman, G R ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Antipsychotics; Hemodialysis; Renal impairment; pharmacokinetics; Schizophrenia; Sertindole

Indexed keywords

CARBON 14; CYTOCHROME P450; DEHYDROSERTINDOLE; DNA; DRUG METABOLITE; PLASMA PROTEIN; SERTINDOLE; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; BODY WEIGHT; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CREATININE CLEARANCE; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG PROTEIN BINDING; GENE MUTATION; GENOTYPE; HEMODIALYSIS; HUMAN; KIDNEY FAILURE; KIDNEY FUNCTION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ADULT; ANTIPSYCHOTIC AGENTS; CREATININE; CYTOCHROME P-450 CYP2D6; HUMANS; IMIDAZOLES; INDOLES; KIDNEY; KIDNEY DISEASES; MALE; METABOLIC CLEARANCE RATE; MIDDLE AGED; RENAL DIALYSIS; SCHIZOPHRENIA;

EID: 0030986727     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050278     Document Type: Article

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