Developmental patterns of serum 3α-androstanediol glucuronide

Journal of Endocrinological Investigation

Volumn 20, Issue 3, 1997, Pages 138-143

  Rittner, H L ^a   Lee, P D K ^b   Blum, W F ^a   Doerr, H G ^c   Steiss, J ^a   Kreuder, J ^a   Rascher, W ^a   Kiess, W ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b Diagnostic Systems Laboratories Inc   (United States)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

17 hydroxyprogesterone; 3 androstanediol; 3 androstanediol glucuronide; Adrenal; Androgens; Congenital adrenal hyperplasia; Puberty

Indexed keywords

ANDROGEN; ANDROSTANEDIOL; ANTISERUM; GLUCURONIDE; MARKER;

ADOLESCENT; ADULT; AGE; ANDROGEN METABOLISM; ARTICLE; BLOOD LEVEL; CHILD; CHILD DEVELOPMENT; DEVELOPMENTAL DISORDER; FEMALE; HUMAN; HUMAN EXPERIMENT; INFANT; MALE; NORMAL HUMAN; PUBERTY; RADIOIMMUNOASSAY; REFERENCE VALUE; SEX DIFFERENCE; SEXUAL DEVELOPMENT;

EID: 0030986576     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03346892     Document Type: Article

References (20)

1. Morimoto I., Edmiston A., Hawks D., Horton R. Studies on the origin of androstanediol and androstanediol glucuronide in young and elderly men. J. Clin. Endocrinol. Metab. 52: 772, 1981.
2. Moghissi E., Ablan F., Horton R. Origin of plasma androstanediol glucuronide in men. J. Clin. Endocrinol. Metab. 59: 417, 1984.
3. Vermeulen A., Giagulli V.A. Physiology of plasma androstanediol glucuronide. J. Ster. Biochem. Mol. Biol. 39: 829, 1991.
4. Rittmaster R.S. Androgen conjugates: Physiology and clinical significance. Endocr. Rev. 14: 121, 1993.
5. Narang R., Rao J., Savjani G., Petersen J. Radioimmunoassay kit for the quantitative measurement of serum androstanediol glucuronide in unextracted serum. Clin. Chem. 37: 1049A, 1991.
6. Andre M., Valsamis J. Reference values for androstanediol glucuronide. Clin. Chem. 40: 162, 1994.
7. Schnakenburg vK., Bidlingmaier F., Knorr D. 17OHprogesterone, androstenedione, and testosterone in normal children and in prepubertal patients with congenital adrenal hyperplasia. Eur. J. Pediatr. 133: 259, 1980.
8. Pang S., MacGillivray M., Wang M., Jeffries S., Clark A., Rosenthal I. 3-androstandediol glucuronide in virilizing congenital adrenal hyperplasia: a useful serum metabolic marker of integrated adrenal androgen secretion. J. Clin. Endocrinol. Metab. 73: 166, 1991.
9. Hatun S., Yordum N., Calikoglu A.S. Serum 3-androstanediol glucuronide measurements in children with congenital adrenal hyperplasia. Eur. J. Endocrinol. 131: 504, 1994.
10. Wudy S.A., Wachter U.A., Homoki J., Teller W.M. 5a-androstane-3, 17β-diol and 5α-androstane-3α, 17β-diol glucuronide in plasma of normal children, adults and patients with idiopathic hirsutism: a mass spectrometric study. Eur. J. Endocrinol. 134: 87, 1996.
11. Meikle A.W., Odell W.D.: Effect of short-and long-term dexamethasone on 3α-androstanediol glucuronide in hirsute women. Fertil Steril 46: 227, 1986.
12. Horton R., Hawks D., Lobo R. 3α, 17β-Androstanediol glucuronide in plasma: a marker of androgen action in idiopathic hirsutism. J. Clin. Invest. 69: 1203, 1982.
13. Paulson R.J., Serafini P.C., Catalino J.A., Lobo R.A. Measurements of 3α, 17β-androstanediol glucuronide in serum and urine and correlation with skin 5α-reductase activity. Fertil. Steril. 46: 222, 1986.
14. Lobo R.A., Shoupe D., Serafini P., Brinton D., Horton H. The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women. Fertil. Steril. 43: 200, 1985.
15. Scanlon M.J., Whorwood C.B., Franks S., Reed M.J., James V.H.T. Serum androstanediol glucuronide concentrations in normal and hirsute women and patients with thyroid dysfunction. Clin. Endocrinol. (Oxf.) 29: 529, 1988.
16. Pang S., Wang G., Jeffries S., Riddick L., Clark A., Estrada E. Normal and elevated 3α-androstanediol glucuronide concentrations in women with various causes of hirsutism and its correlation with degree of hirsutism and androgen levels. J. Clin. Endocrinol. Metab. 75: 243, 1992.
17. Riddick L., Garibaldi L., Wang M., Senne A.R., Klimah P.E., Clark A.T. 3α-androstanediol glucuronide in premature and normal pubarche. J. Clin. Endocrinol. Metab. 72: 46, 1991.
18. Balducci R., Finocchi G., Mangiantini A., Bianchi P., Gugulielmi R., Toscano V. Plasma 3α-androstanediol glucuronide in precocious puberty. J. Endocrinol. Inves. 16: 117, 1993.
19. Reiner B.J., Donohoue P.A., Migeon C.J., Berkovitz G.D. Serum 3α-Androstanediol glucuronide measurements in sexually mature women with congenital adrenal hyperplasia during therapy. J. Clin. Endocrinol. Metab. 69: 105, 1989.
20. Gilad S., Chayen R., Tordjman K., Kisch E., Stern N. Assessment of 5α-reductase activity in hirsute women: comparison of serum androstanediol glucuronide with urinary androsterone and aetiocholanolone excretion. Clin. Endocrinol. (Oxf.) 40: 459, 1994.