Active immunization of rats against insulin β subunits: Effects on sleep and feeding

Physiology and Behavior

Volumn 61, Issue 5, 1997, Pages 649-651

  De Saint Hilaire, Zara ^a   Charnay, Yves ^a   Golaz, Jean ^a   Gaillard, Jean Michel ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Active immunization; Feeding; Insulin ; Rat; Sleep

Indexed keywords

INSULIN;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ARTICLE; FEEDING BEHAVIOR; FOOD INTAKE; INSULIN RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SLEEP; SLEEP PARAMETERS; SLEEP PATTERN;

EID: 0030986372     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(96)00505-7     Document Type: Article

References (19)

1. Aston-Jones G., Bloom F. E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycles. J. Neurosci. 1:1981;876-886.
2. Amir S., Lagiorgia M., Pollack R. Intra-ventromedial hypothalamic injection of insulin suppresses brown fat thermogenesis in the anaesthetized rat. Brain Res. 480:1989;340-343.
3. Bray G. A. Autonomic and endocrine factors in the regulation of food intake. Brain Res. Bull. 14:1985;505-510.
4. Bendtson I., Gade J., Theilgaard A, Binder C. Cognitive function in type 1 (insulin-dependent) diabetic patients after nocturnal hypoglycaemia. Diabetologia. 35:1992;898-903.
5. Booth T. U. Effect of intrahypothalamic glucose injection on eating and drinking elicited by insulin. J. Comp. Physiol. Psychol. 65:1968;13-16.
6. De Saint Hilaire Z., Charnay Y, Gaillard J-M. Active immunization against insulin affects sleep and feeding in rats. Physiol. Behav. 57:1995;803-806.
7. Figlewicz D. P., Szot P., Israel P. A., Payne C., Dorsa D. M. Insulin reduces norepinephrine transporter mRNA in vivo in rat locus caeruleus. Brain Res. 602:1993;161-164.
8. Grossman S. P. The role of glucose, insulin and glucagon in the regulation of food intake and body weight. Neurosci. Behav. Rev. 10:1986;295-315.
9. Harley C. W. A role for norepinephrine in arousal, emotion and learning?: limbic modulation by norepinephrine and the Kety hypothesis. Prog. Neuropsychopharmacol. Biol. Psychiatr. 11:1987;419-458.
10. Sakaguchi T., Takahashi M., Bray G. A. Diurnal changes in sympathetic activity. J. Clin. Invest. 82:1988;282-286.
11. Sangiah S., Calwell D. F. Reduction of rapid eye movement (REM) sleep by glucose alone or glucose and insulin in rats. Life Sci. 42:1988;1425-1429.
12. Schwartz M. W., Figlewicz D. P., Baskin D. G., Woods S. C., Porte D. Insulin in the brain: A hormonal regulator of energy balance. Endocr. Rev. 13:1992;387-414.
13. Shimizu H., Bray G. A. Effects of insulin on hypothalamic monoamine metabolism. Brain Res. 510:1990;251-258.
14. Steffens A. B. The influence of insulin injections and infusions on eating and blood glucose in the rat. Physiol. Behav. 4:1969;823-828.
15. Van Houten M., Posner B. I., Kopriwa B. M., Brawer J. R. Insulin binding in the rat brain: in vivo localization to the circumventricular organs by quantitative autoradiography. Endocrinology. 105:1979;666-673.
16. VanderWeele D. A., Pi-Sunyer F. X., Novin D., Bush M. J. Chronic insulin infusion suppresses food ingestion and body weight gain in rats. Brain Res. Bull. 5:1980;7-11.
17. Wallum B. J., Taborsky C. J. Jr, Porte D. Jr. Cerebrospinal fluid uptake of plasma in humans. J Clin. Endocrinol. Metab. 64:1987;190-194.
18. Wozniak M., Bartoz R., Baker S. P., Raizada M. K. The cellular and physiological actions of insulin in the central nervous system. Neurochem. Int. 22:1993;1-10.
19. Yoshida T., Yoshioka K., Nishioka H., Kondo M. Lesions of the hypothalamic paraventricular nucleus and norepinephrine turnover in rats. Endocrinol. JPN. 36:1989;187-194.