Molecular cloning of mouse liver flavin containing monooxygenase (FMO1) cDNA and characterization of the expression product: Metabolism of the neurotoxin, 1,2,3,4-tetrahydroisoquinoline (TIQ)

Journal of Toxicological Sciences

Volumn 22, Issue 1, 1997, Pages 45-56

  Itoh, Kunio ^a   Nakamura, Kaori ^a   Kimura, Teruyuki ^b   Itoh, Susumu ^a,c   Kamataki, Tetsuya ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b Sandoz Pharmaceuticals Ltd   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

1,2,3,4 Tetrahydroisoquinoline; Flavin containing monooxygenase; Mouse liver; Neurotoxin; Yeast

Indexed keywords

CHLORPROMAZINE; DIMETHYLHYDRAZINE; IMIPRAMINE; N,N DIMETHYLANILINE; NEUROTOXIN; NICOTINE; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TETRAHYDROISOQUINOLINE; THIOACETAMIDE; THIOBENZAMIDE DERIVATIVE; THIOUREA; TRIMETHYLAMINE; UNSPECIFIC MONOOXYGENASE;

ADOLESCENT; AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; LIVER METABOLISM; MALE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION; YEAST;

EID: 0030985787     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.22.45     Document Type: Article

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