Natural product research and the emerging market for biochemical resources

Journal of Research in Pharmaceutical Economics

Volumn 8, Issue 2, 1997, Pages 3-23

  Artuso, Anthony ^a  

^a Department of Teacher Education and Department of Sociology and Anthropology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NATURAL PRODUCT; NEW DRUG;

CONTRACT; DRUG DEVELOPMENT; DRUG INDUSTRY; DRUG RESEARCH; MARKET; PRIORITY JOURNAL; REVIEW;

EID: 0030985598     PISSN: 08966621     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

1. U.S. Department of the Interior. National Park Service. The value of conserving genetic resources, by M. L. Oldfield. Washington, DC: National Park Service, 1984.
2. Klocke JA. Plant compounds as a source and models of insect-control agents. In: Economic and medicinal plant research. Wagner H, Hikino H, Farnsworth N, eds. London: Academic Press Limited, 1989:3:104-44.
3. Myers N. The primary source. New York: Norton & Co., 1992.
4. Broad WJ. Strange oases in sea depths offer map to riches. New York Times 1993 Nov 16:C1.
5. Leary WE. Science takes a lesson from nature: imitating abalone and spider silk. New York Times 1993 Aug 31:C1.
6. Lipton RJ. DNA solution of hard computational problems. Science 1995;268:542-5.
7. Mitscher LA, Drake S, Gollapudi SR, Okwute SK. A modern look at folkloric use of anti-infective agents. J Natural Products 1987;50:1025-40.
8. Borris RP. Industrial pharmacognosy in the 1990's. Presentation to the Conference on Drug Discovery and Commercial Opportunities in Medicinal Plants. Washington, DC. September 19-20, 1994.
9. Hawksworth DL. Microorganisms. In: Global biodiversity. Groombridge B, ed. London: World Conservation Monitoring Centre and Chapman & Hall, 1992.
10. Farnsworth NR, Soejarto DD. Potential consequences of plant extinction in the U.S. on the availability of prescription drugs. Econ Botany 1985;39:231-40.
11. May RM. How many species? Philosophical Trans Royal Soc 1990; B330:293-304.
12. Stork NE. Insect diversity: facts, fiction and speculation. Biological J Linnean Soc 1988;35:321-37.
13. Grifo F. Chemical prospecting: an overview of the International Cooperative Biodiversity Groups Program. In: Emerging connections: biodiversity, biotechnology, and sustainable development. Feinsilver J, ed. Washington, DC: Pan American Health Organization, 1996.
14. Grifo FT, Newman D, Fairfield A, Grupenhoff JT, Bhattacharya B. The origins of prescription drugs. In: Biodiversity and human health. Grifo FT, Rosenthal J, eds. Washington, DC: Island Press, in press.
15. U.S. International Trade Commission. Global competitiveness of U.S. advanced technology manufacturing industries: pharmaceuticals. World Competition 1991;15(2):27-45.
16. Aylward BA. The economic value of pharmaceutical prospecting and its role in biodiversity conservation. LEEC Paper DP 93-03. London: London Environmental Economics Centre, 1993.
17. Mendelsohn R, Balick MJ. The value of undiscovered pharmaceuticals in tropical forests. Econ Botany 1995;49:223-8.
18. Simpson RD, Sedjo RA, Reid JW. Valuing biodiversity for use in pharmaceutical research. J Political Econ 1996;104:1548-70.
19. DiMasi JA, Hansen RW, Grabowski HG, Lasagna L. Cost of innovation in the pharmaceutical industry. J Health Econ 1991;10:107-42.
20. Grabowski H, Vernon J. A new look at the returns and risks to pharmaceutical R&D. Manage Sci 1990;36:804-21.
21. Hansen RW. The pharmaceutical development process: estimates of development costs and times. In: Issues in pharmaceutical health economics. Chien RI, ed. Lexington, MA: Lexington Books, 1979.
22. Armond PA. Beyond the romance of plants: deciding to invest in medicinal plant programs. Presentation to the Conference on Drug Discovery and Commercial Opportunities in Medicinal Plants. Washington, DC. September 19-20, 1994.
23. Houghten RA. Methods for rapid synthesis of large numbers of discrete peptides. In: Macromolecular sequencing and synthesis: selected methods and applications. Schlesinger DH, ed. New York: Alan R. Liss Inc., 1988:185-94.
24. Harris A. Improving molecular diversity of a compound collection in a high throughput screening program. Society for Biomolecular Screening Newsline 1995;1:3.
25. Soejarto D, Farnsworth N. Tropical rainforests: potential sources of new drugs. Perspect Biol Med 1989;32:244-56.
26. Devlin JP. Compound libraries as a discovery resource. Screening Forum 1995;3(1):11.
27. 2 synthase. Nature Structural Biol 1995;2:637-43.
28. Rubeck JR Jr. Synthetic self replicating molecules. Scientific Am 1994;271(1):48-55.
29. Joyce GF. Directed molecular evolution. Scientific Am 1992;267(6):90-7.
30. Hammond P. Species inventory. In: Global biodiversity. Groombridge B, ed. London: World Conservation Monitoring Centre and Chapman & Hall, 1992:17-39.
31. Case KE, Fair RC. Principles of microeconomics. 3rd ed. Englewood Cliffs, NJ: Prentice Hall, 1994.
32. Artuso A. An economic and policy analysis of biochemical prospecting [Dissertation]. Ithaca, NY: Cornell University, 1994.
33. Artuso A. Prospecting on the biomedicinal frontier: an economic and policy analysis of the search, development and marketing of drugs of natural origin. Binghamton, NY: Pharmaceutical Products Press, in press.
34. Artuso A. Capturing the chemical value of biodiversity. In: Biodiversity and human health. Grifo FT, Rosenthal J, eds. Washington, DC: Island Press, 1996.