Synthesis of (R,S)-dioclein, a bioactive flavanone from the root bark of Diocleia grandiflora

Journal of Natural Products

Volumn 60, Issue 4, 1997, Pages 399-400

  Spearing, Paul ^a   Majetich, George ^a   Bhattacharyya, Jnanabrata ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; DIOCLEIN; FLAVANONE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ARTICLE; DRUG CONFORMATION; DRUG ISOLATION; DRUG SYNTHESIS; MEDICINAL PLANT; PLANT ROOT; STRUCTURE ACTIVITY RELATION;

DIOCLEA GRANDIFLORA; DIOCLEIA; DIOCLEIA GRANDIFLORA;

EID: 0030985563     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np960659b     Document Type: Article

References (10)

1. Andrade Lima, D. Plantas da Caatingas; Academia Brasileira de Ciências: Rio de Janeiro, Brazil, 1989; p 112.
2. Batista, J. S.; Almeida, R. N.; Bhattacharyya, J., Abstracts of Papers, II. Congress de la Federacion Farmaceutica Sudamericana, Montevideo, Uruguay, 1993; p 168.
3. Bhattacharyya, J.; Batista, J. S.; Almeida, R. N. Phytochemistry 1995, 38, 277-278.
4. Batista, J. S.; Almeida, R. N.; Bhattacharyya, J. J. Ethnopharmacology 1995, 45, 207-210.
5. Seshadri, T. R. The Chemistry of the Flavonoid Compounds; Geissman, T. A., Ed.; MacMillan: New York, 1962; p 156.
6. Narashimachari, N.; Seshadri, T. R. Proc. Ind. Acad. Sci. 1948, 27A, 223-230.
7. Compound 3 was prepared from 2,5-dihydroxybenzaldehyde (Aldrich Chemical Co.) using standard Williamson ether conditions.
8. Mani, R. I.; Herbert, L.; Manise, D. J. Tenn. Acad. Sci. 1981, 66, 1.
9. Jain, A. C.; Sharma, B. N. Phytochemistry 1973, 12, 1455-1458.
10. Harwood, L. M.; Loftus, G. C.; Oxford, A.; Thomson, C. Synth. Commun. 1990, 20, 649-657.