Augmentation of production of TNF-α and anti-tumour activity by an amphotericin B preparation for clinical use in mice

British Journal of Cancer

Volumn 75, Issue 11, 1997, Pages 1613-1616

  Okutomi, T ^a   Ubukata, T ^a   Yamaoka, K ^a   Abe, S ^a   Yamaguchi, H ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

Amphotericin B; FK 23; Fungizone; Meth A tumour; Tumour necrosis factor alpha

Indexed keywords

AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B DERIVATIVE; ANTINEOPLASTIC AGENT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENTEROCOCCUS FAECALIS; FIBROSARCOMA; IMMUNE SYSTEM; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030983390     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.275     Document Type: Article

References (16)

1. Abe S, Ohashi K, Uchida K, Ikeda T, Kimura S and Yamaguchi H (1993) Antitumor and antimicrobial activities of Enterococcal preparation orally administered to mice. In Immunodulating Drugs, Georgiev VS and Yamaguchi H. (ed.), pp. 372-374. Annals of the New York Academy of Science: New York
2. Chia JKS and Pollack M (1989) Amphotericin B induces tumor necrosis factor production by murine macrophages. J Infect Dis 159: 113-116
3. Chia JKS and McManus EJ (1990) In vitro tumor necrosis factor induction assay for analysis of febrile toxicity associated with amphotericin B preparations. Antimicrob Agents Chemother 34: 906-908
4. Gatanaga T, Noguchi K, Tanabe Y, Inagawa H, Soma GI and Mizuno D (1989) Antitumor effect of systemic administration of novel recombinant tumor necrosis factor (rTNF-S) with less toxicity than conventional rTNF-α in vivo. J Biol Response Mod 8: 278-286
5. Gelfand JA, Kimball K, Burke JF and Dinarello CA (1988) Amphotericin B treatment of human mononuclear cells in vitro results in secretion of tumor necrosis factor and interleukin I. Clin Res 36: 456a
6. Mizuno D (1992) Significance of endogenous production of TNF. In Tumor necrosis factor : Structure-function relationship and clinical application. Osawa T and Bonavida B. (ed.), pp. 1-24. Karger: Basle 1992
7. Okutomi T and Yamazaki M (1988) Augmentation of release of cytotoxin from bone marrow macrophages by IFN-γ. Cancer Res 48: 1808-1811
8. Okutomi T, Nakajima Y, Sakakibara F, Kawauchi H and Yamazaki Y (1987) Induction of release of cytotoxin from murine bone marrow cells by an animal lectin. Cancer Res 47: 47-50
9. Okutomi T, Inagawa H, Nishizawa T, Oshima H, Soma GI and Mizuno D (1990) Priming effect of orally administered muramyl dipeptide on induction of endogenous tumor necrosis factor. J Biol Resp Modif 9: 564-569
10. Old LT (1987) Polypeptide mediator network. Nature 326: 330-331
11. Perfect JR, Granger DL and Durack DT (1987) Effects of antifungal agents and gamma-interferon on macrophage cytotoxicity tor fungi and tumor cells. J Infect Dis 156: 316-323
12. Ruff MR and Gifford GE (1980) Purification and physicochemical characterization of rabbit tumor necrosis factor. J Immunol 125: 1671-1677
13. Sculier JP and Body JJ (1991) Intravenous administration of amphotericin B entrapped in liposomes; induction of high serum levels of TNFα. Ann Oncol 2: 141-144
14. Tokuda Y, Tsujii M, Yamazaki M, Kimura S, Abe S and Yamaguchi H (1993) Augmentation of murine tumor necrosis factor production by amphotericin B in vitro and in vivo. Antimicrob Agents Chemother 37: 2228-2230
15. Wolf JE and Massoff SE (1990) In vivo activation of macrophage oxidative burst activity by cytokines and amphotericin B. Infect Immun 58: 1296-1300
16. Yamaguchi H, Abe S and Tokuda Y (1993) Immunomodulating activity of antifungal drugs. In Immunomodulating Drugs, Georgiev VS and Yamaguchi H. (ed.). pp. 447-457. Annals of the New York Academy of Science: New York