Rapid and sensitive detection of Cell-Associated HIV-1 in latently infected cell lines and in patient cells using Sodium-n-butyrate induction and RT-PCR

Journal of Medical Virology

Volumn 52, Issue 2, 1997, Pages 179-189

  Kashanchi, Fatah ^a   Melpolder, Jacqueline C ^b   Epstein, Jay S ^c   Sadaie, M Reza ^c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Diagnostics; Lymphocytic; Monocytoid cells; PBMC

Indexed keywords

BUTYRIC ACID;

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LATENT VIRUS INFECTION; LYMPHOCYTE; MONOCYTE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BUTYRIC ACID; BUTYRIC ACIDS; COLORING AGENTS; ETHIDIUM; GENE PRODUCTS, GAG; HIV SEROPOSITIVITY; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; POLYMERASE CHAIN REACTION; RNA, VIRAL; SENSITIVITY AND SPECIFICITY; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; VIRUS ACTIVATION; VIRUS LATENCY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030982704     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9071(199706)52:2<179::AID-JMV11>3.0.CO;2-G     Document Type: Article

References (44)

1. Arens M, Joseph T, Nag S, Miller JP, Powderly WG, Ratner L (1993): Alterations in spliced and unspliced HIV-1-specific RNA detection in peripheral blood mononuclear cells of individuals with varying CD4-positive lymphocyte counts. AIDS Research and Human Retroviruses 9:1257-1263.
2. Bukrinsky MI, Stanwick TL, Dempsey MP, Stevenson M (1991): Quiescent T Lymphocytes as an inducible virus reservoir in HIV-1 infection. Science 254:423-427.
3. Carton JA, Melon S, Maradona JA, de Ona M, Asensi V, Martinez A, Carcaba V (1994): Replication indexes of the human immunodeficiency virus: Predictive value of viral culture and blood antigens. Medicina Clinica 102:725-730.
4. Contreras-Ssalazar B, Ehlin-Henriksson B, Klein G, Masucci M (1990): Up-regulation of Epstein-Barr Virus (EBV)-encoded membrane protein LMP in the Burkitt's lymphoma line Daudi after exposure to n-butyrate and after EBV superinfection. Journal of Virology 64:5441-5447.
5. Dimitrov DS, Martin MA (1995): HIV-1 results in the frame. CD4 cell turn over. Nature 375: 194-195.
6. Dickover RE, Garratty EM, Herman SA, Sim MS, Plaeger S, Boyer PJ, Keller M, Deveikis A, Stiehm ER, Bryson YJ (1996): Identification of levels of maternal HIV-1 RNA associated with risk of perinatal transmission. Effect of maternal zidovudine treatment on viral load. Journal of American Medical Association 275:599-605.
7. Embretson J, Zupancic M, Beneke J, Till M, Wolinsky S, Ribas JL, Burke A, Haase AT (1993): Analysis of human immunodeficiency virus-infected tissues by amplification and in situ hybridization reveals latent and permissive infections at single-cell resolution. Proceedings of National Academy of Sciences USA 90:357-361.
8. Fang G, Burger H, Grimson R, Tropper P, Nachman S, Mayers D, Weislow O, Moore R, Reyelt C, Hutcheon N, Baker D, Weiser B (1995): Maternal plasma human immunodeficiency virus type 1 RNA level: A determinant and projected threshold for mother-to-child transmission. Proceedings of National Academy of Sciences USA 92:12100-12104.
9. Ferre F, Marchese AL, Griffin SL, Daigle AE, Richieri SP, Jensen FC, Carlo DJ (1993): Development and validation of a polymerase chain reaction method for the precise quantitation of HIV-1 DNA in blood cells from subjects undergoing a 1-year immunotherapeutic treatment. AIDS 2:S21-27.
10. Fiscus SA, DeGruttola V, Gupta P, Katzenstein DA, Meyer WA 3rd, LoFaro ML, Katzman M, Ragni MV, Reichelderfer PS, Cooms RW (1995): Human immunodeficiency virus type 1 quantitative cell microculture as a measure of antiviral efficacy in a multicenter clinical trial. Journal of Infectious Diseases 171:305-311.
11. Folks TM, Justement J, Kinter A, Dinarello CA, Fauci AS (1987): Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line. Science 238:800-802.
12. Folks TM, Clouse KA, Justement J, Rabson A, Duh E, Kehrl JH, Fauci AS (1989): Tumor necrosis factor a induces expression of human immunodeficiency virus in a chronically infected T-cell clone. Proceedings of National Academy of Sciences USA 86:2365-2368.
13. Frech B, Peterhans E: RT-PCR (1994): 'Background priming' during reverse transcription. Nucleic Acids Research 22:4342-4343.
14. Garbuglia AR, Salvi R, Di Caro A, Montella F, Di Sora F, Recchia O, Delfini C, Benedetto A (1995): Peripheral lymphocytes of clinically non-progressor patients harbor inactive and uninducible HIV pro-viruses. Journal of Medical Virology 46:116-121.
15. Golub EI, Li GR, Volsky DJ (1991): Induction of dormant HIV-1 by sodium butyrate: Involvement of the TATA box in the activation of the HIV-1 promoter. AIDS 5:663-668.
16. Gupta P, Kingsley L, Armstrong J, Ding M, Cottrill M, Rinaldo C (1993): Enhanced expression of human immunodeficiency virus type 1 correlates with development of AIDS. Virology 196:586-595.
17. Henrard DR, Daar E, Farzadegan H, Clark SJ, Philips J, Shaw GM, Busch MP (1995): Virologic and immunologic characterization of symptomatic and asymptomatic primary HIV-1 infection. Journal of Acquired Immune Deficiency Syndrome and Human Retrovirology 9:305-310.
18. Kappes JC, Saag MS, Shaw GM, Hahn BH, Chopra P, Chen S, Emini EA, McFarland R, Yang LC, Piatak M Jr, Lifson JD (1995): Assessment of antiretroviral therapy by plasma viral load testing: Standard and ICD HIV-1 p24 antigen and viral RNA (QC-PCR) assays compared. Journal of Acquired Immune Deficiency Syndrome and Human Retrovirology 10:139-149.
19. Katzenstein DA (1995): Viral phenotype and genotype as markers in clinical trials. Journal of Acquired Immune Deficiency Syndrome and Human Retrovirology 2:S25-34.
20. Kavlick MF, Shirasaka T, Kojima E, Pluda JM, Hui F Jr, Yarchoan R, Mitsuya H (1995): Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving 2′,3′-dideoxy-3′-thiacytidine. Antiviral Research 28:133-146.
21. Kim PK, He S, Ho JL (1994): Rapid culture and quantitation of human immunodeficiency virus type 1 from patient cells without the use of mitogen-stimulated donor cells. Clinical and Diagnostic Laboratory Immunology 1:660-666.
22. Laughlin MA, Zeichner S, Kolson D, Alwine JC, Seshamma T, Pomerantz RJ, Gonzales-Scarano F (1993): Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA. Virology 196:496-505.
23. Lee, TH, Sheppard HW, Reis M, Dondero D, Osmond D, Busch MP (1994): Circulating HIV-1-infected cell burden from seroconversion to AIDS: importance of postseroconversion viral load on disease course. Journal of Acquired Immune Deficiency Syndrome 7:381-388.
24. Luka J, Kallin B, Klein G (1979): Induction of the Epstein-Barr Virus (EBV) cycle in latently infected cells by n -butyrate. Virology 94: 228-231.
25. Melon Garcia S, de Ona Navarro M, Rodriquez Pinto C, Fernandez Urgelles M, Martinez Gutierrez A, de la Iglesia P, Mendez Garcia FJ (1995): Prospective study of antigenemia, plasma viremia and, lymphocytic viremia in HIV-infected hemophiliacs. European Journal of Clinical Microbiolology Infectious Diseases 14:400-405.
26. Mitchell BS, Dhami D, Schumacher U (1992): In situ hybridization: A review of methodologies and applications in the biomedical sciences. Medical Laboratory Sciences 49:107-118.
27. Myers G, Wain-Hobson S, Henderson LE, Korber B, Jeang K-T, Pavlakis GN (eds): (1994): "Human Retroviruses and AIDS: A Compilation and Analysis of Nucleic Acid and Amino Acid Sequences." Los Alamos, CA: Los Alamos National Laboratory.
28. O'Brien WA, Grovit-Ferbas K, Namazi A, Ovcak-Derzic S, Wang HJ, Park J, Yeramaian C, Mao SH, Zack JA (1995): Human immunodeficiency virus-type I replication can be increased in peripheral blood of seropositive patients after influenza vaccination. Blood 86:1082-1089.
29. Patterson BK, Till M, Otto P, Goolsby C, Furtado MR, McBride LJ, Wolinsky SM (1993): Detection of HIV-1 DNA and messenger RNA in individual cells by PCR-driven in situ hybridization and flow cytometry. Science 260:976-979.
30. Piatak M Jr, Saag MS, Yang LC, Clark SJ, Kappes JC, Luk KC, Hahn BH, Shaw GM, Lifson JD (1993): Determination of plasma viral load in HIV-1 infection by quantitative competitive polymerase chain reaction. AIDS 2:S65-71.
31. Pomerantz RJ, Trono D, Feinberg MB, Baltimore D (1990): Cells non-productively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: A molecular model for latency. Cell 61: 1271-1276.
32. Posnett DN, Kabak S, Dobrescu D, Hodtsev AS (1995): The HIV-1 reservoir in distinct V beta subsets of CD4 T cells: Evidence for a putative superantigen. Journal of Clinical Immunology 15:18S-21S.
33. Riggs MG, Whittaker RG, Neumann JR, Ingram VM (1977): n-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells. Nature 268:462-464.
34. Rosenberg ZF, Fauci AS (1989): Induction of expression of HIV in latently or chronically infected cells. AIDS Research and Human Retroviruses 5:1-4.
35. Sadaie MR, Hager GL (1994): Induction of developmentally programmed cell death and activation of HIV by sodium butyrate. Virology 202:513-518.
36. Saksela K, Muchmore E, Girard M, Fultz P, Baltimore D (1993): High viral load in lymph nodes and latent human immunodeficiency virus (HIV) in peripheral blood cells of HIV-1-infected chimpanzees. Journal of Virology 67:7423-7427.
37. Schnittman SM, Greenhouse JJ, Lane, HC, Pierce PF, Fauci AS (1991): Frequent detection of HIV-1-specific mRNAs in infected individuals suggests ongoing active viral expression in all stages of disease. AIDS Research and Human Retroviruses 7:361-367.
38. Sorenson CM, Barry MA, Eastman A (1990): Analysis of events associated with cell cycle arrest at G/S phase and cell death induced by cisplatin. Journal of National Cancer Institute 82:749-755.
39. Tanaka J, Sadanari H, Sato H, Fukuda S (1991): Sodium butyrate-inducible replication of human cytomegalovirus in a human epithelial cell line. Virology 185:271-280.
40. Tetali SK, Oyaizu N, Paul M, Pahwa S (1993): Human immunodeficiency virus type 1 RNA detection in peripheral blood mononuclear cells by polymerase chain reaction: Enhanced sensitivity after mitogenic stimulation. AIDS Research and Human Retroviruses 9:77-82.
41. Udaykumar, Heredia A, Soriano V, Bravo R, Epstein JS, Hewlett IK (1994): Enhanced diagnostic efficiency of the polymerase chain reaction by co-amplification of multiple regions of HIV-1 and HIV-2. Journal of Virological Methods 49:37-46.
42. Urdea MS, Wilber JC, Yeghiazarian T, Todd JA, Kern DG, Fong SJ, Besemer D, Hoo B, Sheridan PJ, Kokka R, Neuwald P, Pachl CA (1993): Direct and quantitative detection of HIV-1 RNA in human plasma with a branched DNA signal amplification assay. AIDS 2:S11-14.
43. van der Burg SH, Visseren MJ, Brandt RM, Kast WM, Melief CJ (1996): Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability. Journal of Immunology 156:3308-3314.
44. Yamamura Y, Rodriguez N, Schwartz A, Eylar E, Yano N (1995): Anti-CD4 cytotoxic T lymphocyte (CTL) activity in HIV+ patients: Flow cytometric analysis. Cellular and Molecular Biology 1:S133-144.