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Volumn 36, Issue 8, 1997, Pages 829-831

Structure-Activity Relationships by NMR: A New Procedure for Drug Discovery by a Combinatorial-Rational Approach

Author keywords

Combinatorial chemistry; Drug research; Proteins; Structure reactivity relationships

Indexed keywords


EID: 0030982328     PISSN: 05700833     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.199708291     Document Type: Review
Times cited : (18)

References (10)
  • 2
    • 84889439852 scopus 로고    scopus 로고
    • One representative review: F. Balkenhohl, C. von dem Bussche-Hünnefeldt, A. Lansky, C. Zechel, Angew. Chem. 1996, 108, 2436-2488; Angew. Chem. Int. Ed. Engl. 1996, 35, 2289-2337.
    • (1996) Angew. Chem. Int. Ed. Engl. , vol.35 , pp. 2289-2337
  • 3
    • 0001129495 scopus 로고    scopus 로고
    • H.-J. Böhm, G. Klebe, Angew. Chem. 1996, 108, 2750-2778; Angew. Chem. Int. Ed. Engl. 1996, 35, 2588-2614.
    • (1996) Angew. Chem. , vol.108 , pp. 2750-2778
    • Böhm, H.-J.1    Klebe, G.2
  • 4
    • 0030474049 scopus 로고    scopus 로고
    • H.-J. Böhm, G. Klebe, Angew. Chem. 1996, 108, 2750-2778; Angew. Chem. Int. Ed. Engl. 1996, 35, 2588-2614.
    • (1996) Angew. Chem. Int. Ed. Engl. , vol.35 , pp. 2588-2614
  • 7
    • 0019407381 scopus 로고
    • 1H HSQC spectra are excellent tools for studying the complexation or modification (such as phosphorylation) of proteins. However, their systematic use for screening libraries and combination with the principle of linking different ligands is novel: W. P. Jencks, Proc. Natl. Acad. Sci. USA 1981, 78, 4046-4050.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 4046-4050
    • Jencks, W.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.