Rimexolone: A new opthalmic corticosteroid with low intraocular pressure-raising potential

Drugs of Today

Volumn 33, Issue 2, 1997, Pages 123-129

  Yang, Jean ^a   Foster, C Stephen ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE SODIUM PHOSPHATE; PREDNISOLONE ACETATE; RIMEXOLONE;

ALLERGIC CONJUNCTIVITIS; ARTICLE; CATARACT; DRUG EFFICACY; DRUG SAFETY; EYE INFLAMMATION; HUMAN; NONHUMAN; TOPICAL DRUG ADMINISTRATION;

EID: 0030982308     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Hench, P.S., Kendall, E.L., Slocomb, C.H., Polley, H.F. Effects of hormone of adrenal cortex (17-hydroxy-11 dehydrocorticosterone: compound E) and of the pituitary adrenocorticotropic hormone on rheumatoid arthritis. Proc Staff Meet Mayo Clin 1949, 24: 181.
2. Gordon, D.M., McLean, J.M. Effects of pituitary adrenocorticotropic hormone (ACTH) therapy in ophthalmologic conditions. JAMA 1950, 142: 1271-5.
3. Woods, A.C. Protein-therapy induced hyperpyrexia. In: Endogenous Uveitis. Williams & Wilkins: Baltimore 1956, 234-8.
4. Hardman, J.G., Gildman, A.G., Limbird, L.E. Inhibitors of the synthesis and actions of adrenocortical hormones. In: Goodman & Gilman's The Pharmacological Basis of Therapeutics. McGraw-Hill: New York 1996, 1466-7.
5. Technical data on file, Alcon Laboratories, Inc.
6. Leibowitz, H.M., Bartlett, J.D., Rich, R., McQuirter, H., Stewart, R., Assil, K. Intraocular pressure-raising potential of 1% rimexolone in patients responding to corticosteroids. Arch Ophthalmol 1996, 114: 933-7.
7. Lehmann, R., Assil, K., Stewart R., Fox, K. Comparison of rimexolone 1% ophthalmic suspension to placebo in control of a postcataract surgery inflammation. Invest Ophthalmol Vis Sci 1995, 36 (4, Suppl.): 5793.
8. Foster, C.S., Alter, G., DeBarge, L.R. et al. Efficacy and safety of rimexolone 1% ophthalmic suspension vs 1% prednisolone acetate in the treatment of uveitis. Am J Ophthalmol 1996, 122: 171-82.