Calcium channel blockers suppress the contact hypersensitivity reaction (CHR) by inhibiting antigen transport and presentation by epidermal Langerhans cells in mice

Clinical and Experimental Immunology

Volumn 108, Issue 2, 1997, Pages 302-308

  Katoh, N ^a   Hirano, S ^a   Kishimoto, S ^a   Yasuno, H ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

B7 1; Ia; migration; nifedipine; verapamil

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; B7 ANTIGEN; CALCIUM CHANNEL BLOCKING AGENT; CD45 ANTIGEN; CD86 ANTIGEN; CONTACT ALLERGEN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IA ANTIGEN; KEYHOLE LIMPET HEMOCYANIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; METHANOL; NIFEDIPINE; VERAPAMIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CONTACT ALLERGY; CONTROLLED STUDY; EPIDERMIS CELL; FLOW CYTOMETRY; LANGERHANS CELL; LYMPH NODE CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOPICAL DRUG ADMINISTRATION;

EID: 0030982092     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1997.d01-1024.x     Document Type: Article

References (58)

1. Stingl G, Hauser C, Tschahler E, Groh V, Wolff K. Immune functions of epidermal cells. In: Norris DA, ed. Immune mechanisms in cutaneous disease. New York: Marcel Dekker Inc., 1989:3-72.
2. Kondo S, Sauder DN. Epidermal cytokines in allergic contact dermatitis. J Am Acad Dermatol 1995; 33:786-800.
3. Sette A, Buus S, Colon S, Smith JA, Miles C, Grey HM. Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells. Nature 1987; 328:395-9.
4. Tamaki K, Stingl G, Guillino M, Sachs DH, Katz SI. Ia antigens in mouse skin are predominantly expressed on Langerhans cells. J Immunol 1979; 123:784-7.
5. Stingl G, Katz SI, Clement L, Green I, Shevach EM. Immunologic functions of Ia-bearing epidermal Langerhans cells. J Immunol 1978; 121:2005-13.
6. Stingl G, Gazze-Stingl LA, Aberer W, Wolff K. Antigen presentation by murine epidermal Langerhans cells and its alteration by ultraviolet B light. J Immunol 1981; 127:1707-13.
7. Romani N, Schuler G, Fritsch P. Identification and phenotype of epidermal Langerhans cells. In: Schuler G, ed. Epidermal Langerhans cells. Boca Raton: CRC Press, 1991:52-66.
8. Blaylock BL, Kouchi Y, Comment CE, Pollock PL, Luster MI. Topical application of T-2 toxin inhibits the contact hypersensitivity response in BALB/c mice. J Immunol 1993; 150:5135-43.
9. Blaylock BL, Kouchi Y, Comment CE, Corsini E, Rosenthal GJ, Luster MI. Pentamidine isethionate reduces Ia expression and antigen presentation by Langerhans cells and inhibits the contact hypersensitivity reaction. J Immunol 1991; 147:2116-21.
10. 2+-calmodulin complex are involved in interferon-γ-induced expression of HLA class II molecules on HL-60 cells. Proc Natl Acad Sci USA 1988; 85:3120-4.
11. Puré E, Inaba K, Crowley MT et al. Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain. J Exp Med 1990; 172:1459-69.
12. Diezel W, Gruner S, Diaz LA, Anhalt GJ. Inhibition of cutaneous contact hypersensitivity by calcium transport inhibitors lanthanum and diltiazem. J Invest Dermatol 1989; 93:322-6.
13. Derrenne F, Vanhaeverbeek M, Brohée D. Nifedipine-induced hyporeactivity in delayed hypersensitivity skin tests. Int J Immunopharmacol 1987; 9:741-4.
14. McFadden J, Bacon K, Camp R. Topically applied verapamil hydrochloride inhibits tuberculin-induced delayed-type hypersensitivity reactions in human skin. J Invest Dermatol 1992; 99:784-6.
15. Corteza Q, Shen S, Revie D, Chretien P. Effects of calcium channel blockers on in vivo cellular immunity in mice. Transplantation 1989; 47:339-42.
16. Birx DL, Berger M, Fleisher TA. The interference of T cell activation by calcium channel blocking agents. J Immunol 1984; 133:2904-9.
17. Linsley PS, Ledbetter JA. The role of the CD 28 receptor during T cell responses to antigen. Annu Rev Immunol 1993; 11:191-212.
18. Garrigue JL, Nicolas JF, Fraginals R, Benezra C, Bour H, Schmitt D. Optimization of the mouse ear swelling test for in vivo and in vitro studies of weak contact sensitizers. Contact Dermatitis 1994; 30:231-7.
19. Koyama Y, Hachiya T, Hagiwara M et al. Expression of protein kinase C isozyme in epidermal Langerhans cells of the mouse. J Invest Dermatol 1990; 94:677-80.
20. Aiba S, Katz SI. Phenotypic and functional characteristics of in vivo-activated Langerhans cells. J Immunol 1990; 145:2791-6.
21. Becker D, Reske-Kunz AB, Knop J, Reske K. Biochemical properties of MHC class II molecules endogenously synthesized and expressed by mouse Langerhans cells. Eur J Immunol 1991; 21:1213-20.
22. Macatonia SE, Knight SC, Edwards AJ, Griffiths S, Fryer P. Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies. J Exp Med 1987; 166:1654-67.
23. Kraal G, Breel M, Janse M, Bruin G. 'Langerhans' cells, veiled cells and interdigitating cells in the mouse recognized by a monoclonal antibody. J Exp Med 1986; 163:981-7.
24. Melamed D, Friedman A. In vivo tolerization of Th1 lymphocytes following a single feeding with ovalbumin: anergy in the absence of suppression. Eur J Immunol 1994; 24:1974-81.
25. Melamed D, Friedman A. Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin. Eur J Immunol 1993; 23:935-42.
26. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-PhOH-chloroform extraction. Anal Biochem 1987; 162:156-9.
27. Lee MG, Borkowski TA, Udey MC. Regulation of expression of B7 by murine Langerhans cells: a direct relationship between B7 mRNA levels and the level of surface expression of B7 by Langerhans cells. J Invest Dermatol 1993; 101:883-6.
28. Freeman G, Borriello F, Hodes R et al. Murine B7-2, an alternative CTLA-4 counter-receptor that costimulates T cell proliferation and interleukin 2 production. J Exp Med 1993; 178:2185-92.
29. Kripke ML, Munn CG, Jeevan A, Tung J, Bucana C. Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization. J Immunol 1990; 145:2833-8.
30. Schuler G, Steinman RM. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro. J Exp Med 1985; 161:526-46.
31. Shimada S, Caughman SR, Sharrow SO, Stephany D, Katz SI. Enhanced antigen-presenting capacity of cultured Langerhans cells is associated with markedly increased expression of Ia antigen. J Immunol 1987; 139:2551-5.
32. Yokozeki H, Katayama I, Ohki O et al. Functional CD86 (B7-2/B70) on cultured human Langerhans cells. J Invest Dermatol 1996; 106:147-53.
33. Bieber T, Jürgens M, Wollenberg A, Sander E, Hanau D, de la Salle H. Characterization of the protein tyrosine phosphatase CD45 on human epidermal Langerhans cells. Eur J Immunol 1995; 25:317-21.
34. Enk AH, Katz SI. Early molecular events in the induction phase of contact hypersensitivity. Proc Natl Acad Sci USA 1991; 89:1398-402.
35. Walus KM, Fondacaro JD, Jacobson ED. Effects of calcium and its antagonists on the canine mesenteric circulation. Circ Res 1981; 48:692-700.
36. ++ antagonist-induced vasodilation. Circ Res 1983; 52:137-42.
37. Braunwald E. Mechanism of action of calcium channel blocking agents. N Engl J Med 1982; 307:1618-27.
38. Lee KS, Tsein RW. Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialyzed heart cells. Nature 1983; 302:790-4.
39. Bacon KB, Westwick J, Camp RDR. Potent and specific inhibition of IL-8-, IL-1α- and IL-1β-induced in vitro human lymphocyte migration by calcium channel antagonists. Biochem Biophys Res Commun 1989; 165:349-54.
40. 45Ca uptake and histamine release in rat mast cells induced by various stimulating agents. Int Arch Allergy Appl Immunol 1983; 72:102-9.
41. Wright B, Zeidman I, Greig R, Poste G. Inhibition of macrophage activation by calcium channel blockers and calmodulin antagonists. Cell Immunol 1985; 95:46-53.
42. Shen H, Wiederhold MD, Ou DW. The suppression of macrophage secretion by calcium blockers and adenosine. Immunopharmacol Immunotoxicol 1995; 17:301-9.
43. Pickard S, Shankar G, Burnham K. Langerhans' cell depletion by staphylococcal superantigens. Immunology 1994; 83:568-72.
44. Yamashita K, Yano A. Migration of murine epidermal Langerhans cells to regional lymphnodes: engagement of major histocompatibility complex class II antigens induces migration of Langerhans cells. Microbiol Immunol 1994; 38:567-84.
45. Mommaas AM, Mulder AA, Out CJ et al. Distribution of HLA class II molecules in epidermal Langerhans cells in situ. Eur J Immunol 1995; 25:520-5.
46. Halliday GM, Lucas AD. Protein kinase C transduces the signal for Langerhans cell migration from the epidermis. Immunology 1993; 79:621-6.
47. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 1992; 258:607-14.
48. Mooney NA, Grillot Courvalin C, Hivroz C, Ju LY, Charron D. Early biochemical events after MHC class II-mediated signaling on human B lymphocytes. J Immunol 1990; 145:2070-6.
49. Scholl PR, Trede N, Chatila TA, Geha RS. Role of protein tyrosine phosphorylation in monokine induction by the staphylococcal superantigen toxic shock syndrome toxin-1. J Immunol 1992; 148:2237-41.
50. Xu S, Ariizumi K, Caceres-Dittmar D et al. Successive generation of antigen-presenting, dendritic cell lines from murine epidermis. J Immunol 1995; 154:2697-705.
51. Longley J, Ding TG, Levin D et al. Regulation of transgenic class II major histocompalibility genes in murine Langerhans cells. J Invest Dermatol 1995; 104:329-34.
52. Gimmi CD, Freeman GJ, Gribben JG, Gray G, Nadler LM. Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc Natl Acad Sci USA 1993; 90:6586-90.
53. Buelens C, Willems F, Delvaux A et al. Interleukin-10 differentially regulates B7-1 (CD80) and B7-2 (CD86) expression on human peripheral blood dendritic cells. Eur J Immunol 1995; 25:2668-72.
54. Larsen CP, Ritchie SC, Hendrix R, Linsley PS, Hathcock KS, Hodes RJ, Lowly RP, Pearson TC. Regulation of immunostimulatory function and costimulatory molecules (B7-1 and B7-2) expression on murine dendritic cells. J Immunol 1994; 152:5208-19.
55. Triggle DJ, Swamy VC. Calcium antagonists: some chemical-pharmacologic aspects. Circ Res 1983; 52 (Suppl. I): 17-28.
56. Millard RW, Grupp G, Grupp IL, DiSalvo J, DePover A, Schwarts A. Chronotropic, ionotropic and vasodilator actions of diltiazem, nifedipine, and verapamil: a comparative study of physiological responses and membrane receptor activity. Circ Res 1983; 52 (Suppl. I):29-39.
57. Robertson DRC, Waller DG, Renwick AG, George CF. Age-related changes in the pharmacokinetics and pharmacodymanics of nifedipine. Br J Clin Pharmacol 1988; 25:297-305.
58. McMillen MA, Tesi RJ, Baumgarten WB, Jaffe BM, Wait RB. Polentiation of cyclosporine by verapamyl in vitro. Transplantation 1985; 40:444-5.