Petrolatum prevents irritation in a human cumulative exposure model in vivo

Dermatology

Volumn 194, Issue 3, 1997, Pages 247-250

  Wigger Alberti, W ^a   Eisner, P ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Chromametry; Irritant contact dermatitis; Petrolatum; Protective creams; Repetitive irritation test (RIT); Transepidermal water loss (TEWL); Visual score

Indexed keywords

DODECYL SULFATE SODIUM; LACTIC ACID; PETROLATUM; PROTECTIVE AGENT; SODIUM HYDROXIDE; TOLUENE; WHITE PETROLATUM;

ADULT; ARTICLE; BACK; COLORIMETRY; CONTROLLED STUDY; EPIDERMIS; FEMALE; HUMAN; HUMAN EXPERIMENT; IRRITANT DERMATITIS; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SCORING SYSTEM; SKIN; SKIN WATER LOSS; STANDARD;

EID: 0030981503     PISSN: 10188665     EISSN: 14219832     Source Type: Journal    
DOI: 10.1159/000246112     Document Type: Article

References (22)

1. Tronnier H: Methodische Ansätze zur Prüfung von Hautschutzmitteln. Dermatosen 1993:41: 100-107.
2. Treffei P. Gabard B. Juch R: Evaluation of barrier creams: An in vitro technique on human skin. Acta Derm Venereol (Stöckli) 1994:74: 7-11.
3. Marks R. Dykes PJ. Hamami I: Two novel techniques for the evaluation of barrier creams. Br J Dermatol 1989;120:655-660.
4. Boman A. Mellstrom G: Percutaneous absorption of 3 organic solvents in the guinea pig. III. Effect of barrier creams. Contact Dermatitis 1989:21:134-140.
5. Frosch PJ. Kurte A. Pilz B: Efficacy of skin barrier creams. III. The repetitive irritation test (RIT) in humans. Contact Dermatitis 1993:29: 113-118.
6. Frosch PJ. Kurte A: Efficacy of skin barrier creams. IV. The repetitive irritation test (RIT) w ith a set of 4 standard irritants. Contact Dermatitis 1994:31:161-168.
7. Frosch PJ. Schulze DA. Hoffmann M. Axthelm I. Kurte A: Efficacy of skin barrier creams. I. The repetitive irritation test (RIT) in the guinea pig. Contact Dermatitis 1993:28:94-100.
8. Frosch PJ. Schulze-Dirks A. Hoffmann M. Axthelm I: Efficacy of skin harrier creams. II. Ineffectiveness of a popular 'skin protector' against various irritants in the repetitive irritation test in the guinea pig. Contact Dermatitis 1993:29:74-77.
9. Goh CL: Cutting oil dermatitis on guinea pig skin. I. Cutting oil dermatitis and barrier cream. Contact Dermatitis 1991:24:16-21.
10. Grünewald AM. Gloor M. Gehring W. Kleesz, P: Efficacy of skin barrier creams; in Eisner P. Maibach HI (eds): Irritant Dermatitis: New Clinical and Experimental Aspects. Basel. Karger 1994, pp 187-197.
11. Mahmoud G. Lachapelle JM. Van Neste D: Histological assessment of skin damage by irritants: Its possible use in the evaluation of a 'barrier cream'. Contact Dermatitis 1984:11: 179-185.
12. Mahmoud G. Lachapelle JM: Evaluation of the protective value of an antisolvent gel by laser Doppler flowmetry and histology. Contact Dermatitis 1985:13:14-19.
13. Schlüter-Wigger W. Eisner P: Efficacy of 4 commercially available protective creams in the repetitive irritation test (RIT). Contact Dermatitis 1996:34:278-283.
14. Willis CM. Stephens JM. Wilkinson JD: Experimentally induced irritant contact dermatitis. Contact Dermatitis 1988:18:20-24.
15. Pinnagoda J. Tupker RA. Agner T. Setup J: Guidelines for transepidermal water loss (TEWL) measurement: A report from the Standardization Group of the European Society of Contact Dermatitis. Contact Dermatitis 1990: 22:164-178.
16. Robertson AR: The CIE 1976 color differences formulas. Color Res Application 1977:2:7-11.
17. Eisner P: Irritant dermatitis in the workplace. Dermatol Clin 1994:12:461-467.
18. Flesch P: Chemical basis of emollient function in horny layers. Proc Sci Sect Toilet Goods Assoc 1963:40:1-7.
19. Mao-Qiang M. Brown BE. Wu-Pong S. Feingold KR. Elias PM: Exogenous nonphysi-ologic vs. physiologic lipids: Divergent mechanisms for correction of permeability barrier dysfunction. Arch Dermatol 1995:131: 809-816.
20. Blanken R. Van Vilsteren MJT. Tupker RA. Coenraads PJ: Effect of mineral oil and linoleic-acid-containing emulsions on the skin vapour loss of sodium-lauryl-sulphate-induced irritant skin reactions. Contact Dermatitis 1989:20:93-97.
21. Rietschel RL: A method to evaluate skin moisturizers in vivo. J Invest Dermatol 1978:70: 152-155.
22. Ghiadially R. Halkier-Sorensen L. Elias PM: Effects of petrolatum on stratum corneum structure and function. J Am Acad Dermatol 1992:26:387-396.