-
1
-
-
0027109075
-
p53, guardian of the genome
-
News
-
D. P. Lane, p53, guardian of the genome. Nature 358, 15-16 (1992). [News]
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
2
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
E. R. Fearon and B. Vogelstein, A genetic model for colorectal tumorigenesis. Cell 61, 759-767 (1990).
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
3
-
-
0027499458
-
Molecular mechanisms of carcinogenesis in humans and rodents
-
J. C. Barrett and M. Anderson, Molecular mechanisms of carcinogenesis in humans and rodents. Mol. Carcinogen. 7, 1-13 (1993).
-
(1993)
Mol. Carcinogen.
, vol.7
, pp. 1-13
-
-
Barrett, J.C.1
Anderson, M.2
-
4
-
-
0025894713
-
p53 mutations in human cancers
-
M. Hollstein, D. Sidransky, B. Vogelstein and C. C. Harris, p53 mutations in human cancers. Science 253, 49-53 (1991).
-
(1991)
Science
, vol.253
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
5
-
-
0027756186
-
p53: At the crossroads of molecular carcinogenesis and risk assessment
-
C. C. Harris, p53: at the crossroads of molecular carcinogenesis and risk assessment. Science 262, 1980-1981 (1993).
-
(1993)
Science
, vol.262
, pp. 1980-1981
-
-
Harris, C.C.1
-
6
-
-
0028868527
-
p53: A cell cycle regulator activated by DNA damage
-
G. Selivanova and K. G. Wiman, p53: a cell cycle regulator activated by DNA damage. Adv. Cancer Res. 66, 143-177 (1995).
-
(1995)
Adv. Cancer Res.
, vol.66
, pp. 143-177
-
-
Selivanova, G.1
Wiman, K.G.2
-
7
-
-
0023939945
-
Retinoblastoma and the progression of tumor genetics
-
M. F. Hansen and W. F. Cavenee, Retinoblastoma and the progression of tumor genetics. Trends Genet. 4, 125-128 (1988).
-
(1988)
Trends Genet.
, vol.4
, pp. 125-128
-
-
Hansen, M.F.1
Cavenee, W.F.2
-
8
-
-
0021632346
-
The genetics of retinoblastoma
-
R. S. Sparkes, The genetics of retinoblastoma. Biochim. Biophys. Acta 780, 95-118 (1985).
-
(1985)
Biochim. Biophys. Acta
, vol.780
, pp. 95-118
-
-
Sparkes, R.S.1
-
9
-
-
0020679049
-
Patient with 13 chromosome deletion: Evidence that the retinoblastoma gene is a recessive cancer gene
-
W. F. Benedict, A. L. Murphree, A. Banerjee, C. A. Spina, M. C. Sparkes and R. S. Sparkes, Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene. Science 219, 973-975 (1983).
-
(1983)
Science
, vol.219
, pp. 973-975
-
-
Benedict, W.F.1
Murphree, A.L.2
Banerjee, A.3
Spina, C.A.4
Sparkes, M.C.5
Sparkes, R.S.6
-
10
-
-
0023777950
-
Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma
-
J. Toguchida, K. Ishizaki, M. Sasaki, M. Ikenaga, M. Sugimoto, Y. Kotokura and T. Yamamoto, Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma. Cancer Res. 48, 3939-3943 (1988).
-
(1988)
Cancer Res.
, vol.48
, pp. 3939-3943
-
-
Toguchida, J.1
Ishizaki, K.2
Sasaki, M.3
Ikenaga, M.4
Sugimoto, M.5
Kotokura, Y.6
Yamamoto, T.7
-
11
-
-
0019830333
-
Post-translational regulation of the 54k cellular tumor antigen in normal and transformed cells
-
M. Oren, W. Maltzman and A. J. Levine, Post-translational regulation of the 54k cellular tumor antigen in normal and transformed cells. Mol. Cell. Biol. 1, 101-110 (1981).
-
(1981)
Mol. Cell. Biol.
, vol.1
, pp. 101-110
-
-
Oren, M.1
Maltzman, W.2
Levine, A.J.3
-
12
-
-
0025248598
-
Activation mutations in p53 produce a common conformational effect: A monoclonal-antibody specific for the mutant form
-
J. V. Gannon, R. Greaves, R. Iggo and D. P. Lane, Activation mutations in p53 produce a common conformational effect: A monoclonal-antibody specific for the mutant form. EMBO J. 12, 1021-1028 (1990).
-
(1990)
EMBO J.
, vol.12
, pp. 1021-1028
-
-
Gannon, J.V.1
Greaves, R.2
Iggo, R.3
Lane, D.P.4
-
13
-
-
0027496935
-
The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinase
-
J. W. Harper, G. R. Adami, N. Wei, K. Keyomarsi and S. J. Elledge, The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinase. Cell 75, 805-816 (1993).
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
14
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
W. S. El-Deiry, T. Tokino, V. E. Velculescu, D. B. Levy, R. Parsons, J. Trent, D. Lin, W. E. Mercer, K. W. Kinzler and B. Vogelstein, WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825 (1993).
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
15
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinase
-
Y. Xiong, G. J. Hannon, H. Zhang, D. Casso, R. Kobayashi and D. Beach, p21 is a universal inhibitor of cyclin kinase. Nature 366, 701-704 (1993).
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
16
-
-
0028006035
-
Cancer incidence in atomic bomb survivors: Part II. Solid tumors, 1958-1987
-
D. E. Thompson, K. Mabuchi, E. Ron, M. Soda, M. Tokunaga, S. Ochikubo, S. Sugimoto, T. Ikeda, M. Terasaki, S. Izumi and D. L. Preston, Cancer incidence in atomic bomb survivors: Part II. Solid tumors, 1958-1987. Radiat. Res. 137, S17-S67 (1994).
-
(1994)
Radiat. Res.
, vol.137
-
-
Thompson, D.E.1
Mabuchi, K.2
Ron, E.3
Soda, M.4
Tokunaga, M.5
Ochikubo, S.6
Sugimoto, S.7
Ikeda, T.8
Terasaki, M.9
Izumi, S.10
Preston, D.L.11
-
17
-
-
0025110091
-
The effects of high-LET radiation at low doses/dose rates
-
Meeting report with extended abstracts
-
M. Charles, R. Cox, D. Goodhead and A. Wilson, The effects of high-LET radiation at low doses/dose rates. Int. J. Radiat. Biol. 58, 859-885 (1990). [Meeting report with extended abstracts]
-
(1990)
Int. J. Radiat. Biol.
, vol.58
, pp. 859-885
-
-
Charles, M.1
Cox, R.2
Goodhead, D.3
Wilson, A.4
-
18
-
-
0021212968
-
Tumor induction in BALB/c mice after fractionated or protracted exposures to fission-spectrum neutrons
-
R. L. Ullrich, Tumor induction in BALB/c mice after fractionated or protracted exposures to fission-spectrum neutrons. Radiat. Res. 97, 587-597 (1984).
-
(1984)
Radiat. Res.
, vol.97
, pp. 587-597
-
-
Ullrich, R.L.1
-
20
-
-
0003766319
-
-
Report ANL-95/3, Argonne National Laboratory, Argonne, IL
-
D. Grahn, B. J. Wright, B. A. Carnes, F. S. Williamson and C. Fox, Studies of Acute and Chronic Radiation Injury at the Biological and Medical Research Division, Argonne National Laboratory, 1970-1992: The JANUS Program Survival and Pathology Data. Report ANL-95/3, Argonne National Laboratory, Argonne, IL, 1995.
-
(1995)
Studies of Acute and Chronic Radiation Injury at the Biological and Medical Research Division, Argonne National Laboratory, 1970-1992: The JANUS Program Survival and Pathology Data
-
-
Grahn, D.1
Wright, B.J.2
Carnes, B.A.3
Williamson, F.S.4
Fox, C.5
-
21
-
-
24444478622
-
-
Report ANL-86-33, NUREG/CR 4704, Argonne National Laboratory, Argonne, IL
-
D. Grahn, J. F. Thomson and B. Carnes, Relative Biological Effectiveness (RBE) of Fission Neutrons and Gamma Rays at Occupational Exposure Levels: Vol. III. Studies on the Gross Microscopic Pathology Observed at Death of Mice Exposed to 60 Equal Once-Weekly Doses of Fission Neutrons and Gamma Rays. Report ANL-86-33, Vol. III (NUREG/CR 4704, Vol. II), Argonne National Laboratory, Argonne, IL, 1990.
-
(1990)
Relative Biological Effectiveness (RBE) of Fission Neutrons and Gamma Rays at Occupational Exposure Levels: Vol. III. Studies on the Gross Microscopic Pathology Observed at Death of Mice Exposed to 60 Equal Once-Weekly Doses of Fission Neutrons and Gamma Rays
, vol.2-3
-
-
Grahn, D.1
Thomson, J.F.2
Carnes, B.3
-
23
-
-
0028270201
-
Detection of retinoblastoma gene deletions in spontaneous and radiation-induced mouse lung adenocarcinomas by polymerase chain reaction
-
M. E. Churchill, M. A. Gemmell and G. E. Woloschak, Detection of retinoblastoma gene deletions in spontaneous and radiation-induced mouse lung adenocarcinomas by polymerase chain reaction. Radiat. Res. 137, 310-316 (1994).
-
(1994)
Radiat. Res.
, vol.137
, pp. 310-316
-
-
Churchill, M.E.1
Gemmell, M.A.2
Woloschak, G.E.3
-
24
-
-
0026451101
-
p53 mutations and protein accumulation during multistage human esophageal carcinogenesis
-
W. P. Bennett, M. C. Hollstein, R. A. Metcalf, J. A. Welsh, A. He, S. M. Zhu, I. Kusters, J. H. Resau, B. F. Trump, D. P. Lane and C. C. Harris, p53 mutations and protein accumulation during multistage human esophageal carcinogenesis. Cancer Res. 52, 6092-6097 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 6092-6097
-
-
Bennett, W.P.1
Hollstein, M.C.2
Metcalf, R.A.3
Welsh, J.A.4
He, A.5
Zhu, S.M.6
Kusters, I.7
Resau, J.H.8
Trump, B.F.9
Lane, D.P.10
Harris, C.C.11
-
25
-
-
0024317643
-
Structure and expression of the murine retinoblastoma gene and encoded protein
-
R. Bernards, G. M. Schackleford, M. R. Gerber, J. M. Horowitz, S. H. Friend, M. Schartl, E. Bogenmann, J. M. Rapaport, T. McGee, T. P. Dryja and R. A. Weinberg, Structure and expression of the murine retinoblastoma gene and encoded protein. Proc. Natl. Acad. Sci. USA 86, 6474-6478 (1989).
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 6474-6478
-
-
Bernards, R.1
Schackleford, G.M.2
Gerber, M.R.3
Horowitz, J.M.4
Friend, S.H.5
Schartl, M.6
Bogenmann, E.7
Rapaport, J.M.8
McGee, T.9
Dryja, T.P.10
Weinberg, R.A.11
-
28
-
-
0022079123
-
Neoplastic transformation is enhanced by multiple low doses of fission-spectrum neutrons
-
C. K. Hill, B. A. Carnes, A. Han and M. M. Elkind, Neoplastic transformation is enhanced by multiple low doses of fission-spectrum neutrons. Radiat. Res. 102, 404-410 (1995).
-
(1995)
Radiat. Res.
, vol.102
, pp. 404-410
-
-
Hill, C.K.1
Carnes, B.A.2
Han, A.3
Elkind, M.M.4
-
29
-
-
0027403439
-
The inverse dose-rate effect for oncogenic transformation by charged particles is dependent on linear energy transfer
-
R. C. Miller, G. Randers-Pehrson, L. Heiber, S. A. Marino, M. Richards and E. J. Hall, The inverse dose-rate effect for oncogenic transformation by charged particles is dependent on linear energy transfer. Radiat. Res. 133, 360-364 (1993).
-
(1993)
Radiat. Res.
, vol.133
, pp. 360-364
-
-
Miller, R.C.1
Randers-Pehrson, G.2
Heiber, L.3
Marino, S.A.4
Richards, M.5
Hall, E.J.6
-
30
-
-
0027394720
-
Mechanistic considerations on the dose-rate/LET dependence of oncogenic transformation by ionizing radiations
-
D. J. Brenner, E. J. Hall, G. Randers-Pehrson and R. C. Miller, Mechanistic considerations on the dose-rate/LET dependence of oncogenic transformation by ionizing radiations. Radiat. Res. 133, 365-369 (1993).
-
(1993)
Radiat. Res.
, vol.133
, pp. 365-369
-
-
Brenner, D.J.1
Hall, E.J.2
Randers-Pehrson, G.3
Miller, R.C.4
-
31
-
-
0002452020
-
Radiation-induced mutation in mammalian cells at low doses and dose rates
-
(O. F. Nygaard, W. K. Sinclair and J. T. Lett, Eds.), Academic Press, San Diego
-
J. Thacker, Radiation-induced mutation in mammalian cells at low doses and dose rates. In Advances in Radiation Biology, Vol. 16 (O. F. Nygaard, W. K. Sinclair and J. T. Lett, Eds.), pp. 77-124. Academic Press, San Diego, 1992.
-
(1992)
Advances in Radiation Biology
, vol.16
, pp. 77-124
-
-
Thacker, J.1
-
32
-
-
0001205905
-
Track structure considerations in low dose and low dose rate effects of ionizing radiation
-
(O. F. Nygaard, W. K. Sinclair and J. T. Lett, Eds.), Academic Press, San Diego
-
D. T. Goodhead, Track structure considerations in low dose and low dose rate effects of ionizing radiation. In Advances in Radiation Biology, Vol. 16 (O. F. Nygaard, W. K. Sinclair and J. T. Lett, Eds.), pp. 7-45. Academic Press, San Diego, 1992.
-
(1992)
Advances in Radiation Biology
, vol.16
, pp. 7-45
-
-
Goodhead, D.T.1
-
33
-
-
0006065347
-
Spatial and temporal distribution of energy
-
D. T. Goodhead, Spatial and temporal distribution of energy. Health Phys. 55, 231-240 (1988).
-
(1988)
Health Phys.
, vol.55
, pp. 231-240
-
-
Goodhead, D.T.1
-
34
-
-
0021186864
-
Overview and prospects of the application of fast neutrons in cancer therapy
-
A. Wambersie, G. W. Barendsen and N. Breteau, Overview and prospects of the application of fast neutrons in cancer therapy. J. Eur. Radiother. 5, 248-264 (1984).
-
(1984)
J. Eur. Radiother.
, vol.5
, pp. 248-264
-
-
Wambersie, A.1
Barendsen, G.W.2
Breteau, N.3
-
35
-
-
0022254220
-
The molecular nature of mutations in cultured mammalian cells: A review
-
J. Thacker, The molecular nature of mutations in cultured mammalian cells: a review. Mutat. Res. 150, 431-442 (1985).
-
(1985)
Mutat. Res.
, vol.150
, pp. 431-442
-
-
Thacker, J.1
-
37
-
-
0026021882
-
Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product
-
W. G. Kaelin, D. C. Pallas, J. A. DeCaprio, F. J. Kaye and D. M. Livingston, Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell 64, 521-532 (1991).
-
(1991)
Cell
, vol.64
, pp. 521-532
-
-
Kaelin, W.G.1
Pallas, D.C.2
DeCaprio, J.A.3
Kaye, F.J.4
Livingston, D.M.5
-
38
-
-
1842364831
-
-
R. G. Landes, Georgetown, TX
-
J. W. Ludlow and G. R. Skuse, Tumor Suppressors, Involvement in Human Diseases, Viral Protein Interactions and Growth Regulation. R. G. Landes, Georgetown, TX, 1994.
-
(1994)
Tumor Suppressors, Involvement in Human Diseases, Viral Protein Interactions and Growth Regulation
-
-
Ludlow, J.W.1
Skuse, G.R.2
-
39
-
-
0025879530
-
Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies
-
J. Bartek, J. Bartkova, B. Vojtesek, Z. Staskova, J. Lukas, A. Rejthar, J. Kovarik, C. A. Midgley, J. V. Gannon and D. P. Lane, Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies. Oncogene 6, 1699-1703 (1991).
-
(1991)
Oncogene
, vol.6
, pp. 1699-1703
-
-
Bartek, J.1
Bartkova, J.2
Vojtesek, B.3
Staskova, Z.4
Lukas, J.5
Rejthar, A.6
Kovarik, J.7
Midgley, C.A.8
Gannon, J.V.9
Lane, D.P.10
-
40
-
-
0028371994
-
A presumed B6 strain-specific p53 polymorphism is confined to a B6 cell line and is likely to represent a facilitating mutation
-
T. Paunesku, M. A. Gemmell, R. Crkvenjakov and G. E. Woloschak, A presumed B6 strain-specific p53 polymorphism is confined to a B6 cell line and is likely to represent a facilitating mutation. Mamm. Genome 5, 106-107 (1994).
-
(1994)
Mamm. Genome
, vol.5
, pp. 106-107
-
-
Paunesku, T.1
Gemmell, M.A.2
Crkvenjakov, R.3
Woloschak, G.E.4
-
41
-
-
0028172645
-
p53 deletion as a genetic marker in urothelial tumor by fluorescence in situ hybridization
-
H. Matsuyama, Y. Pan, E. A. Mahdy, P. U. Malmstrom, A. Hedrum, M. Uhlen, C. Busch, T. Hirano, G. Auer, B. Tribukait, K. Naito, P. Lichter, P. Ekman and U. S. R. Bergerheim, p53 deletion as a genetic marker in urothelial tumor by fluorescence in situ hybridization. Cancer Res. 54, 6057-6060 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 6057-6060
-
-
Matsuyama, H.1
Pan, Y.2
Mahdy, E.A.3
Malmstrom, P.U.4
Hedrum, A.5
Uhlen, M.6
Busch, C.7
Hirano, T.8
Auer, G.9
Tribukait, B.10
Naito, K.11
Lichter, P.12
Ekman, P.13
Bergerheim, U.S.R.14
-
42
-
-
0028222545
-
Physical deletion of the p53 gene in bladder-cancer: Detection by fluorescence in-situ hybridization
-
G. Sauter, G. R. Deng, H. Moch, R. Kerschmann, K. Matsumura, S. Devries, T. George, J. Fuentes, P. Carroll, M. J. Mihatsch and F. M. Waldman, Physical deletion of the p53 gene in bladder-cancer: detection by fluorescence in-situ hybridization. Am. J. Pathol. 144, 756-766 (1984).
-
(1984)
Am. J. Pathol.
, vol.144
, pp. 756-766
-
-
Sauter, G.1
Deng, G.R.2
Moch, H.3
Kerschmann, R.4
Matsumura, K.5
Devries, S.6
George, T.7
Fuentes, J.8
Carroll, P.9
Mihatsch, M.J.10
Waldman, F.M.11
-
43
-
-
0027935784
-
Rb tumor suppressor gene expression in hepatocellular carcinomas from patients infected with the hepatitis-B virus
-
C. C. Hsia, A. M. Dibisceglie, D. E. Kleiner, M. Farshid and E. Tabor, Rb tumor suppressor gene expression in hepatocellular carcinomas from patients infected with the hepatitis-B virus. J. Med. Virol. 44, 67-73 (1994).
-
(1994)
J. Med. Virol.
, vol.44
, pp. 67-73
-
-
Hsia, C.C.1
Dibisceglie, A.M.2
Kleiner, D.E.3
Farshid, M.4
Tabor, E.5
-
44
-
-
0026683175
-
p53 mutations in human lung tumors
-
C. W. Miller, K. Simon, A. Also, K. Kok, J. Yokata, C. H. C. M. Buys, M. Terada and H. P. Koeffler, p53 mutations in human lung tumors. Cancer Res. 52, 1695-1698 (1992).
-
(1992)
Cancer Res.
, vol.52
, pp. 1695-1698
-
-
Miller, C.W.1
Simon, K.2
Also, A.3
Kok, K.4
Yokata, J.5
Buys, C.H.C.M.6
Terada, M.7
Koeffler, H.P.8
|