New procedures to measure synthase and phosphatase activities of bisphosphoglycerate mutase. Interest for development of therapeutic drugs

Comptes Rendus de l'Academie des Sciences - Serie III

Volumn 320, Issue 1, 1997, Pages 27-33

  Ravel, Pascale ^a   Garel, Marie Claude ^a   Toullec, Dominique ^b  

^a HENRI MONDOR HOSPITAL   (France)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

2,3 DPG; Bisphosphoglycerate mutase; Synthase and phosphatase activities

Indexed keywords

2,3 DIPHOSPHOGLYCERIC ACID; BISPHOSPHOGLYCERATE MUTASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLYCERALDEHYDE 3 PHOSPHATE; HEMOGLOBIN; PHOSPHATASE; PHOSPHOGLYCERATE MUTASE; SYNTHETASE; TRIOSEPHOSPHATE ISOMERASE;

ALLOSTERISM; ARTICLE; CHROMATOGRAPHY; DRUG DEVELOPMENT; ENZYME ACTIVITY; ENZYME ASSAY; ERYTHROCYTE; ESCHERICHIA COLI; ISCHEMIA; NONHUMAN; PAPER ELECTROPHORESIS; REDUCTION; SICKLE CELL ANEMIA;

EID: 0030981384     PISSN: 07644469     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0764-4469(99)80083-3     Document Type: Article

References (16)

1. Benesch R., Benesch R.E. 1967. The effect of organic phosphates from the human erythrocyte on allosteric properties of hemoglobin. Biochem. Biophys. Res. Comm. 26, 162-167
2. Lenfant C., Torrance J., English E., Finch C.A., Reynfarge C., Ramos J., Faura J. 1968. Effect of altitude on oxygen binding by hemoglobin on organic phosphate levels. J. Clin. Invest. 47, 2652-2655
3. Oski F.A., Gottlieb A.J., Delivoria-Papadopoulos M., Miller W.W. 1969. Red cell 2,3-diphosphoglycerate levels in subjects with chronic hypoxemia. New Engl. J. Med. 280, 1165-117
4. 2 affinity of hemoglobin on work performance during exercise in healthy humans. J. Lab. Clin. Med. 104, 166-175
5. Poillon W.N., Kim B.C., Labotka R.J., Hicks C.U., Kark J.A. 1995. Antisickling effect of 2,3-diphosphoglycerate depletion. Blood 85, 3289-3296
6. Rapoport S., Luebering J. 1950. The formation of 2,3-diphosphoglycerate in rabbit erythrocytes: the existence of diphosphoglycerate mutase. J. Biol. Chem. 183, 507-516
7. Rosa R., Gaillardon J., Rosa J. 1973. Diphosphoglycerate mutase and 2,3-diphosphoglycerate phosphatase activities of red cells: comparative electrophoretic study. Biochem. Biophys. Res. Comm. 51, 536-542
8. Rosa R., Audit I., Rosa J. 1975. Evidence for three enzymatic activities in one electrophoretic band of 3-phosphoglycerate mutase from red cells. Biochimie 57, 1059-1063
9. Ikura K., Marita H., Sasaki R., Chiba H. 1978. Immunochemical and enzymatic properties of biphosphoglyceromutase/phosphatase and phosphoglyceromutase from human erythrocytes. Eur. J. Biochem. 89, 23-31
10. Roze Z.B., Liebowitz J. 1970. 2,3-Diphosphoglycerate phosphatase from human erythrocytes. General properties and activation by anions J. Biol. Chem. 245, 3232-3241
11. Fothergill-Gilmore L.A., Watson H.C. 1989. The phosphoglycerate mutase. In: Advances in Enzymology (Meister A., ed), John Wiley and Sons, New York, 62, 227-313
12. Yu K.J., Pendley IIC., Hierczed T., Pendleton R.G. 1989. 2,3-Diphosphoglycerate phosphatase/synthase: a potential target for elevating the diphosphoglycerate level in human red blood cells. J. Pharmacol. Exp. Therapeutics 252, 192-200
13. Rosa R., Prehu M.O., Beuzard Y., Rosa J. 1978. The first case of complete deficiency of diphosphoglycerate mutase in human erythrocytes. J. Clin. Invest. 62, 907-915
14. Garel M.C., Lemarchandel V., Calvin M.C., Arous N., Craescu C.T., Prehu M.O., Rosa, J., Rosa R. 1993. Amino acid residues involved in the catalytic site of human erythrocyte bisphosphoglycerate mutase. Eur. J. Biochem. 213, 493-500
15. Garel M.C., Joulin V., Leboulch P., Calvin M.C., Prehu M.O., Arous N., Longin R., Rosa R., Rosa J., Cohen-Solal M. 1989. Human bisphosphoglycerate mutase. Expression in Escherichia coli and use of site-directed mutagenesis in the evaluation of the role of the carboxyl-terminal region in the enzymatic mechanism. J. Biol. Chem. 264, 18966-18972
16. Calvin M.C., Blouquit Y., Garel M.C., Prehu M.O., Cohen-Solal M., Rosa J., Rosa R. 1990. Human bisphosphoglycerate mutase expressed in E. coil: purification, characterization and structure studies. Biochimie 72, 337-343