TCR γδ+ cells are prominent in normal bovine skin and express a diverse repetoire of antigen receptors

Immunology

Volumn 91, Issue 1, 1997, Pages 58-64

  Hein, W R ^a   Dudler, L ^a  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATTLE; EPIDERMIS; NONHUMAN; PRIORITY JOURNAL; SKIN; T LYMPHOCYTE SUBPOPULATION;

EID: 0030981351     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1997.00224.x     Document Type: Article

References (21)

1. - γ/δ T lymphocytes. Eur J Immunol 20, 809.
2. HEIN W.R. & MACKAY C.R. (1991) Prominence of γδ T cells in the ruminant immune system. Immunol Today 12, 30.
3. HEIN W.R., DUDLER L. & MORRIS B. (1990) Differential peripheral expansion and in vivo antigen reactivity of α/β and γ/δ T cells emigrating from the early fetal lamb thymus. Eur J Immunol 20, 1805.
4. HEIN W.R. (1994) Ontogeny of T cells. In: Cell Mediated Immunity in Ruminants (eds B.M.L. Goddeeris & W.I. Morrison) p. 19. CRC Press, Boca Raton.
5. - γ/δ T lymphocytes. J Immunol 152, 3476.
6. WALKER I.D., GLEW M.D., O'KEEFE M.A. et al. (1994) A novel multi-gene family of sheep γδ T cells. Immunology 83, 517.
7. ISHIGURO N. & HEIN W.R. (1994) The T cell receptor. In: Cell Mediated Immunity in Ruminants (eds B.M.L. Goddeeris & W.I. Morrison), p. 59. CRC Press, Boca Raton.
8. HEIN W.R. (1997) Molecular genetics of immune molecules. In: Genetics of the Sheep (eds L. Piper & A. Ruvinsky), in press. CAB International, Oxon.
9. ALLISON J.P. & HAVRAN W.L. (1991) The immunobiology of T cells with invariant γδ antigen receptors. Annu Rev Immunol 9, 679.
10. HEIN W.R. & DUDLER L. (1993) Divergent evolution of Tcell repertoires: extensive diversity and developmentally regulated expression of the sheep γδ T cell receptor. EMBO J 12, 715.
11. MACKAY C.R. & HEIN W.R. (1989) A large proportion of bovine T cells express the γδ T cell receptor and show a distinct tissue distribution and surface phenotype. Int Immunol 1, 540.
12. ISHIGURO N., AIDA Y., SHINAGAWA, T. et al. (1993) Molecular structures of cattle T-cell receptor gamma and delta chains predominantly expressed on peripheral blood lymphocytes. Immunogenetics 38, 437.
13. CURTIS S.E. (1983) Environmental Management in Animal Agriculture. Iowa State Press, Ames, IA.
14. TSCHACHLER E., SCHULER G., HUTTERER, J. et al. (1983) Expression of Thy-1 antigen by murine epidermal cells. J Invest Dermatol 81, 282.
15. BERGSTRESSER P.R., TIGELAAR R.E., DEES, J.H. et al. (1983) Thy-1 antigen-bearing dendritic cells populate murine epidermis. J Invest Dermatol 81, 286.
16. BUCY R.P., CHEN, C-L.H. & COOPER M.D. (1989) Tissue localization and CD8 accessory molecule expression of Tγδ cells in humans. J Immunol 142, 3045.
17. FOSTER C.A., YOKOZEKI H., RAPPERSBERGER, K. et al. (1990) Human epidermal T-cells predominantly belong to the lineage expressing α/β T-cell receptor. J Exp Med 171, 997.
18. + dendritic epidermal cells. Cell 55, 837.
19. GROH V., PORCELLI S., FABBI, M. et al. (1989) Human lymphocytes bearing T cell receptor γ/δ are phenotypically diverse and evenly distributed throughout the lymphoid system. J Exp Med 169, 1277.
20. HEIN W.R. (1997) Assessment of B and T cell antigen receptor repertoires by PCR amplification and cloning. In: Manual of Immunological Methods (ed. I. Lefkovits), p. 2157. Academic Press Inc., London.
21. HEIN W.R. (1994) Structural and functional evolution of the extracellular regions of T cell receptors. Sem Immunol 6, 361.