In vitro and ex vivo anti-human immunodeficiency virus (HIV) activities of a new water-soluble HIV protease inhibitor, R-87366, containing (2S,3S)- 3-amino-2-hydroxy-4-phenylbutanoic acid

Biological and Pharmaceutical Bulletin

Volumn 20, Issue 2, 1997, Pages 175-180

  Komai, Tomoaki ^a   Yagi, Ryuichi ^a   Suzuki Sunagawa, Hisayo ^a   Sakurai, Mitsuya ^a   Higashida, Susumu ^a   Sugano, Machiko ^a   Handa, Hiroshi ^b   Mohri, Hiroshi ^c   Yasuoka, Akira ^c   Oka, Shinichi ^c   Yabe, Yuichiro ^a   Nishigaki, Takashi ^a,c   Kimura, Satoshi ^c   Shimada, Kaoru ^c  

^a DAIICHI SANKYO CO   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

3 amino 2 hydroxy 4 phenylbutanoic acid; AIDS; ex vivo assay; HIV 1 protease inhibitor

Indexed keywords

3 AMINO 2 HYDROXY 4 PHENYLBUTYRIC ACID; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BUTYRIC ACID DERIVATIVE; GAG PROTEIN; PROTEINASE INHIBITOR; R 87366; UNCLASSIFIED DRUG; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INHIBITION KINETICS; MONONUCLEAR CELL; VIRUS CONCENTRATION;

EID: 0030981293     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.20.175     Document Type: Article

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