A physiologically based pharmacokinetic model for retinoic acid and its metabolites

Journal of the American Academy of Dermatology

Volumn 36, Issue 3 SUPPL., 1997, Pages

  Clewell III, H J ^a   Andersen, M E ^a   Wills, R J ^a   Latriano, L ^a  

^a ICF INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EMOLLIENT AGENT; RETINOIC ACID;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DETOXIFICATION; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG GLUCURONIDATION; DRUG METABOLISM; HUMAN; HUMAN CELL; HUMAN TISSUE; MONKEY; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHOTODERMATOSIS; PREDICTION; PRIORITY JOURNAL; RADIOACTIVITY; RAT; TERATOGENICITY; TOPICAL DRUG ADMINISTRATION;

EID: 0030980661     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0190-9622(97)70063-X     Document Type: Article

References (21)

1. HJ Clewell III ME Andersen MG MacNaughton Toxicokinetics: an analytical tool for assessing chemical hazards to man Aviat Space Environ Med 59 suppl 11 1988 A125 A131
2. HJ Clewell III ME Andersen Physiologically-based pharmacokinetic modeling and bioactivation of xenobiotics J Toxicol Indust Health 10 1994 1 24
3. HJ Clewell III ME Andersen Biologically motivated models for chemical risk assessment Health Phys 57 suppl 1 1989 129 137
4. KB Bischoff RL Dedrick DS Zaharko Methotrexate pharmacokinetics J Pharm Sci 60 1971 1128 1133
5. RJ Lutz RL Dedrick HB Matthews A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat Drug Metab Dispos 5 1977 386 396
6. RJ Lutz RL Dedrick D Tuey Comparison of the pharmacokinetics of several polychlorinated biphenyls in mouse, rat, dog, and monkey by means of a physiological pharmacokinetic model Drug Metab Dispos 12 1984 527 535
7. DB Tuey HB Matthews Distribution and excretion of 2,2`,4,4`,5,5`hexabromobiphenyl in rats and man: pharmacokinetic model predictions Toxicol Appl Pharmacol 53 1980 420 431
8. JW Fisher TA Whittaker DH Taylor Physiologically based pharmacokinetic modeling of the pregnant rat: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid Toxicol Appl Pharmacol 99 1989 395 414
9. EJ O'Flaherty W Scott C Schreiner A physiologically based kinetic model of rat and mouse gestation: disposition of a weak acid Toxicol Appl Pharmacol 112 1992 245 256
10. JR Kalin ME Starling DL Hill Disposition of all- trans -retinoic acid in mice following oral doses Drub Metab Dispos 9 1981 196 201
11. M Asai W Faber L Neth Human placental transport and metabolism of all- trans -retinoic acid in vitro Placenta 12 1982 367 368
12. MH Zile RC Inhorn HF DeLuca Metabolites of all- trans -retinoic acid in bile: identification of all- trans - and 13- cis -retinoyl glucuronides J Biol Chem 257 1982 3537 3543
13. BN Swanson CA Frolik DW Zaharevitz Dose-dependent kinetics of all- trans -retinoic acid in rats: plasma levels and excretion into bile, urine, and faeces Biochem Pharmacol 30 1981 107 113
14. PC Adamson FM Balis MA Smith Dose-dependent pharmacokinetics of all- trans -retinoic acid J Natl Cancer Inst 84 1992 1332 1335
15. JC Kraft W Slikker Jr JR Bailey Plasma pharmacokinetics and metabolism of 13- cis - and all- trans -retinoic acid in the cynomolgus monkey and the identification of 13- cis - and all- trans -retinoyl-β-glucuronides Drub Metab Dispos 19 1991 317 324
16. JRF Muindi SR Frankel C Huselton Clinical pharmacology of oral all- trans retinoic acid in patients with acute promyelocytic leukemia Cancer Res 52 1992 2138 2142
17. L Latriano The percutaneous absorption of topically applied tretinoin and its effect on endogenous concen-trations of tretinoin and its metabolites following single doses or long-term use J Am Acad Dermatol 36 1997 S37 S46
18. JJ Kamm KO Ashenfelter CW Ehmann Preclinical and clinical toxicology of selected retinoids MB Sporn AB Roberts DS Goodman The retinoids 1984 Academic Press, Inc Orlando, Fla 287
19. RE Seegmiller WH Ford MW Carter A developmental toxicity study of tretinoin administered topically and orally to pregnant Wistar rats J Am Acad Dermatol 36 1997 S60 S66
20. AG Hendrickx H Hummler Teratogenicity of all- trans -retinoic acid during early embryonic development in the cynomolgus monkey (Macaca fascicularis) Teratology 45 1992 65 74
21. K-C Khoo D Reik WA Colburn Pharmacokinetics of isotretinoin following a single oral dose J Clin Pharmacol 22 1982 395 402