Decreased renal accumulation of biotinylated chimeric monoclonal antibody-neocarzinostatin conjugate after administration of avidin

Japanese Journal of Cancer Research

Volumn 88, Issue 2, 1997, Pages 205-212

  Otsuji, Eigo ^a   Yamaguchi, Toshiharu ^a   Yamamoto, Kazuhito ^a   Matsumura, Hiroomi ^a   Tsuruta, Hiroshi ^a   Yata, Yoshihiro ^a   Nishi, Hiroshi ^a   Okamoto, Kazuma ^a   Kitamura, Kazuya ^a   Takahashi, Toshio ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Avidin biotin complex; Biotinylated antibody; Chimeric antibody; Pancreatic cancer

Indexed keywords

ANTINEOPLASTIC AGENT; AVIDIN; BIOTIN; CHIMERIC ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; IODINE 125; MONOCLONAL ANTIBODY; ZINOSTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; DRUG ACCUMULATION; DRUG CONJUGATION; DRUG LIVER LEVEL; HUMAN; HUMAN CELL; KIDNEY DISEASE; KIDNEY FAILURE; MALE; NEPHROTOXICITY; NONHUMAN; NUDE MOUSE; PANCREAS CANCER; PRIORITY JOURNAL; SPLEEN;

EID: 0030980474     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1997.tb00367.x     Document Type: Article

References (26)

1. Apelgren, L. D Zimmerman, D. L Briggs, S. L. and Bumol, T. F. Antitumor activity of monoclonal antibodyVinca alkaloid immunoconjugate LY203725 (KS1/4-4desacetylvinblastine-3-carboxyhydrazide) in a nude mouse model of human ovarian cancer. Cancer Res 50, 3540- 3544 1990).
2. Hurwitz, E Levy, R., Maron, R Wilchek, M Arnon, R. and Sela, M. The covalent binding of daunomycin and adriamycin to antibodies, with retention of both drug and antibody activities. Cancer Res 35, 1175-1181 1975).
3. Fukuda, K. The study of targeting chemotherapy against gastrointestinal cancer. Akita J. Med 12, 451-468 1985).
4. Takahashi, T Yamaguchi, T., Kitamura, K Suzuyama, H Honda, M. and Hashimoto, Y. Clinical application of monoclonal antibody-drug conjugates for immunotargeting chemotherapy of colorectal carcinoma. Cancer, 61, 881-888 (1988).
5. LoBugli, A. F Saleh, M., Peterson, L Wheeler, R Carrano, R Huster, W. and Khazaeli, M. B. Phase 1 clinical trial of CO17-1A monoclonal antibody. Hybridoma, 5, S117-S123 (1986).
6. Blottiere, H. M Maurel, C. and Douillard, J. Y. Immune function of patients with gastrointestinal carcinoma after treatment with multiple infusions of monoclonal antibody 17.1A. Cancer Res 47, 5238-5241 1987).
7. Takahashi, T Yamaguchi, T., Kitamura, K Noguchi, A Honda, M. and Otsuji, E. Follow-up study of patients treated with monoclonal antibody-drug conjugate: report of 77 cases with colorectal cancer. Jpn. J. Cancer Res 84, 976-981 (1993).
8. Yamaguchi, T Tsurumi, H., Kitamura, K Otsuji, E Miyagaki, T Kotani, T. and Takahashi, T. Production, binding and cytotoxicity of human/mouse chimeric monoclonal antibody-neocarzinostatin conjugate. Jpn. J. Cancer Res 84, 1190-1194 1993).
9. Otsuji, E Yamaguchi, T., Yamaoka, N Taniguchi, K Kato, M Kotani, T Kitamura, K. Takahashi, T. Biodistribution of neocarzinostatin conjugated to chimeric fab fragments of the monoclonal antibody A7 in nude mice bearing human pancreatic cancer xenografts. Jpn. J. Cancer Res 85, 530-535 (1994).
10. Otsuji, E Yamaguchi, T., Yamaoka, N Kotani, T Kato, M. and Taniguchi, K. Biodistribution of murine and chimeric Fab fragments of the monoclonal antibody A7 in human pancreatic cancer. Pancreas, 10, 265-273 (1995).
11. Mock, D. M. and DuBois, D. B. A sequential, solid-phase assay for biotin in physiologic fluids that correlates with expected biotin status. Ann. Biochem 153, 272-278 1986).
12. 14]biotin for kinetic studies and for assay. Biochem. J 89, 585-591 1963).
13. Hnatowich, D. J Virzi, F. and Rusckowski, M. Investigations of avidin and biotin for imaging applications. J. Nucl. Med 28, 1294-1302 1987).
14. Sinitsyn, V. V Mamontova, A. G Checkneva, Y. Y Shnyra, A. A. and Domogatsky, S. P. Rapid blood clearance of biotinylated IgG after infusion of avidin. J. Nucl. Med 30, 66-69 (1989).
15. Ogihara, I Sasaki, T., Toyama, H Oda, K Senda, M. and Nishigori, H. Rapid tumor imaging by active background reduction using biotin-bearing liposomes and avidin. Cancer Res 54, 463-467 (1994).
16. Otsuji, E Yamaguchi, Y., Yanamaguchi, N Koyama, K Imanishi, J Yamaoka, N. and Takahashi, T. Expression of the cell surface antigen detected by the monoclonal antibody A7 in pancreatic carcinoma cell lines. Surg. Today, 22, 351-356 (1992).
17. 131I-labelled human growth hormone of high specific activity. Nature, 194, 495-496 (1962).
18. Spiegelberg, H. L. and Weigle, W. O. The catabolism of homologous and heterologous 7s gamma globulin fragments. J. Exp. Med 121, 323-338 1965).
19. Sutherland, R Buchegger, F., Scheyer, M Vacca, A. and Mach, J. P. Penetration and binding of radiolabeled anti-carcinoembryonic antigen monoclonal antibodies and their antigen binding fragments in human colon multicellular tumor spheroids. Cancer Res 47, 1627-1633 1987).
20. Fujita, H Nakayama, N., Sawabe, T. and Kimura, K. In vivo distribution and inactivation of neocarzinostatin. Jpn. J. Antibiot 23, 471-478 (1970).
21. Otsuji, E Yamaguchi, T., Tsuruta, H Yata, Y Nishi, H Okamoto, K Kitamura, K. and Takahashi, T. Effects of neocarzinostatin-chimeric Fab conjugates on the growth of human pancreatic carcinoma xenografts. Br. J. Cancer, 73, 1178-1182 1996).
22. Marshall, D Pedley, R. B Melton, R. G Boden, J. A Boden, R. and Begent, R. H. J. Galactosylated streptavidin for improved clearance of biotinylated intact and F (ab')2 fragments of an anti-tumour antibody, Br. J. Cancer, 71, 18-24 (1995).
23. Sung, C Osdol, W. V Saga, T Neumann, R Dedrick, R Weinstein, J. Streptavidin distribution in metastatic tumors pretargeted with a biotinylated monoclonal antibody: theoretical and experimental pharmacokinetics. Cancer Res 54, 2166-2175 1994).
24. Saga, T Weinstein, N. W Jeong, J. M Heya, T Lee, J. T Le, N. and Paik, C. H. Two-step targeting of experimental lung metastasis with biotinylated antibody and radiolabeled Streptavidin. Cancer Res 54, 2160-2165 1994).
25. Yokota, T Otsuji, E., Noguchi, A Yamaguchi, T Sawai, K Takahashi, T. Antigenic modulation and internalization of monoclonal antibody to human colonic carcinoma cells detected by enzyme-linked immunosorbent assay. Int. J. Cancer, 44, 1095-1099 1989).
26. Paganeeli, G Perves, S., Siccardi, A. G Rowlinson, G Deleige, G Chiolerio, F Malcovati, M Seassellati, G. A. and Epenetos, A. A. Intraperitoneal radio-localization of tumors pre-targeted by biotinylated monoclonal antibodies. Int. J. Cancer, 45, 1184-1189 1990).