HNK-1 epitope in the lens-ciliary zonular region in normal and pseudoexfoliative eyes:Immunohistochemistry and ultrastructure

Archives of Ophthalmology

Volumn 115, Issue 5, 1997, Pages 637-644

  Qi, Yue ^a   Streeten, Barbara W ^a   Wallace, Robert N ^a  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE ANTIGEN; EPITOPE;

ADOLESCENT; ADULT; AGED; AGING; ANTIGEN DETECTION; ARTICLE; CELL ULTRASTRUCTURE; CHILD; CILIARY BODY; CLINICAL ARTICLE; ELASTIC FIBER; HUMAN; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; INFANT; LENS CAPSULE; LENS LUXATION; PRIORITY JOURNAL;

EID: 0030979798     PISSN: 00039950     EISSN: None     Source Type: Journal    
DOI: 10.1001/archopht.1997.01100150639012     Document Type: Article

References (29)

1. Abo T, Balch CM. A differentiation antigen of human NK and K cells identified by a monoclonal antibody (HNK-1). J Immunol. 1981;127:1024-1029.
2. Kruse J, Mailhammer R, Wernecke H, et al. Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1. Nature. 1984;311:153-155.
3. Kruse J, Keilbaner G, Faissner A, Timpl R, Schachner M. The J1 glycoprotein: a novel nervous system cell adhesion molecule of the L2/HNK-1 family. Nature. 1985;316:146-148.
4. Margolis RK, Ripelliao JA, Goossen B, Steinbrich R, Margolis RU. Occurrence of the HNK-1 epitope (3-sulfoglucuronic acid) in PC12 pheochromocytoma cells, chromaffin granule membranes, and chondroitin sulfate proteoglycans. Biochem Biophys Res Commun. 1987;145:1142-1148.
5. Gowda DC, Margolis RU, Margolis RK. Presence of the HNK-1 epitope on poly (N-acetyllactosaminyl) oligosaccharides and identification of multiple core proteins in the chondroitin sulfate proteoglycans of brain. Biochemistry. 1989;28:4468-4474.
6. Shibata S, Takagaki K, Nakamura T, et al. HNK-1-reactive novel oligosaccharide, sulfate-0-3GlcA beta 1-4xyl beta 1-(4-methyl umbelliferone), synthesized by cultured human skin fibroblasts. J Biol Chem. 1995;270:13794-13798.
7. Pedraza L, Spagnol G, Latov H, Salzer JL. Biosynthesis and regulation of expression of the HNK-1 epitope on myelin-associated glycoprotein in a transfected cell model system. J Neurosci Res. 1995;40:716-727.
8. 2--independent manner. J Cell Biol. 1992;119:1335-1345.
9. Martini R. Expression and functional roles of neural cell surface molecules and extracellular matrix components during development and regeneration of peripheral nerves. J Neurocytol. 1994;23:1-28.
10. Vogel M, Zimmermann H, Singer W. Transient association of the HNK-1 epitope with 5′-nucleotidase during development of the cat visual cortex. Eur J Neurosci. 1993;5:1423-1425.
11. Bronner-Fraser M. Perturbation of cranial neural crest migration by the HNK-1 antibody. Dev Biol. 1987;123:321-331.
12. Hall H, Liu L, Schmitz B. The L2/HNK-1 carbohydrate mediates adhesion of neural cells to laminin. Eur J Neurosci. 1993;5:34-42.
13. Kivelä T. Expression of the HNK-1 carbohydrate epitope in human retina and retinoblastoma: an immunohistochemical study with the anti-Leu-7 monoclonal antibody. Virchows Arch A Pathol Anat. 1986;410:139-146.
14. Uusitalo M, Kivelä T, Tarkkanen A. Identification of a novel element in the human eye: the inner connective tissue layer of the ciliary body characterized with antibodies to the HNK-1 epitope. Invest Ophthalmol Vis Sci. 1993;34:2372-2381.
15. Uusitalo M, Kivelä T, Tarkkanen A. Immunoreactivity of exfoliation material for the cell adhesion-related HNK-1 carbohydrate epitope. Arch Ophthalmol. 1993;111:1419-1423.
16. Uusitalo M, Kivelä T, Tarkkanen A. The HNK-1 epitope in the inner connective tissue layer of the human ciliary body in exfoliation syndrome and various types of glaucoma. Graefes Arch Clin Exp Ophthalmol. 1994;232:8-15.
17. Qi Y, Wallace RN, Hoepner JA, Streeten BW. HNK-1 epitope in normal and pseudoexfoliative (PSX) lens capsules by TEM, Invest Ophthalmol Vis Sci. 1995;36(suppl):829. Abstract.
18. Uusitalo M. Immunohistochemical localization of chondroitin sulfate proteoglycan and tenascin in the human eye compared with the HNK-1 epitope. Graefes Arch Clin Exp Ophthalmol. 1994;232:657-665.
19. Loveless RW, Floyd-O'Sullivan G, Raynes JG, Yuen CT, Feizi T. Human serum amyloid P is a multi-specific adhesive protein whose ligands include 6-phosphorylated mannose and the 3-sulfated saccharides galactose, N-acetylgalactosamine and glucuronic acid. EMBO J. 1992;11:813-819.
20. Li ZY, Streeten BW, Yohai N. Amyloid P protein in pseudoexfoliative fibrillopathy. Cm Eye Res. 1989;8:217-227.
21. Schlözer-Schrehardt U, Dorfler S, Naumann GOH. Immunohistochemical localization of basement membrane components in pseudoexfoliation material of the lens capsule. Curr Eye Res. 1992;11:343-355.
22. Schlözer-Schrehardt U, Kuchle M, Dorfler S, Naumann GOH. Pseudoexfoliative material In the eyelid skin of pseudoexfoliation-suspect patients: a clinicohistopathlogical correlation. Ger J Ophthalmol. 1993;2:51-60.
23. Streeten BW, Li Z-Y, Wallace RN, Eagle RC, Keshgegian M. Pseudoexfoliative fibrillopathy in visceral organs of a patient with pseudoexfoliation syndrome. Arch Ophthalmol. 1992;110:1757-1762.
24. Streeten BW. Aberrant synthesis and aggregation of elastic components in pseudoexfoliative fibrillopathy: a unifying concept. New Trends Ophthalmol. 1993;8:187-196.
25. Streeten BW, Dark AJ, Wallace RN, Li Z-Y, Hoepner JA Pseudoexfoliative fibrillopathy in the skin of patients with ocular pseudoexfoliation. Am J Ophthalmol. 1990;110:490-499.
26. Streeten BW, Gibson SA, Dark AJ. Pseudoexfoliative material contains an elastic microfibrillar-associated glycoprotein. Trans Am Ophthalmol Soc. 1986;84:304-320.
27. Hietanen J, Uusitalo M, Tarkkanen A, Kivela T. Lectin and immunonistochemical comparison of glycoconjugates in the conjunctiva of patients with and without exfoliation syndrome. Br J Ophthalmol. 1995;79:467-472.
28. Streeten BW, Licari PA. The zonules and the elastic microfibrillar system in the ciliary body. Invest Ophthalmol Vis Sci. 1983;24:667-681.
29. Domowicz M, Li H, Hennig A, et al. The biochemically and immunological distinct CSPG of notochord is a product of the aggrecan gene. Dev Biol. 1995;171:655-664.