A short-term study of the effects of SBHAN, a novel compound, on gingival inflammation in the beagle dog

Journal of Periodontology

Volumn 68, Issue 5, 1997, Pages 448-455

  Cutler, Christopher W ^a,b   Ghaffar, Khaled A ^c  

^a BAYLOR COLLEGE OF DENTISTRY   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c Cairo University   (Egypt)

Author keywords

gingivitis drug therapy; N bis 2 (hydroxylethyl) aminoacetate sodium N

Indexed keywords

ACETIC ACID DERIVATIVE; ANTIINFECTIVE AGENT; CHLORHEXIDINE; CHLORHEXIDINE GLUCONATE; N,N BIS(2 HYDROXYETHYL)AMINOACETATE; NEW DRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOG; DRUG EFFICACY; FEMALE; GINGIVITIS; NONHUMAN;

EID: 0030978930     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.1997.68.5.448     Document Type: Article

References (20)

1. Wilson K, Walker JM, eds. Principles and Techniques of Practical Biochemistry, 4th ed. New York: Cambridge Press; 1994;164-165.
2. Lemasters JJ, Peng X, Bachman S, Currin RT, Gao W, Thurman RG. Dual role of kupffur cell activation and endothelial cell damage in reperfusion injury to livers stored for transplantation surgery. J Gastroenterol Hepatol 1995;10:S84-S87.
3. Monahan JB, Handelmann GE, Hood WF, Cordi AA. D-cycloserine. a positive modulator or the N-methyl-D-aspartate receptor, enhances performance of learning tasks in rats. Pharmacol Biochem Behavior 1989;34:649-653.
4. Heaton MP, Johnston RB, Thompson TL. Controlled cell lysis and protoplast formation by enhancement of inhibitors of alanine racemase by glycine. Biochem Biophys Res Commun 1987;149:576-579.
5. Holt SC, Ebersole J, Felton J, Brunsvold M, Kornman KS. Implantation of Bacteroides gingivalis in nonhuman primates initiates progression of periodontitis. Science 1988;239:55-57.
6. Page RC, Schroeder HE. Periodontitis in Man and Other Animals. A Comparative Review. Basel: Karger; 1982;30-46.
7. Groisman M, Klinge B. Clinical and histological findings in ligatureinduced experimental periodontitis in dogs. J Clin Periodontol 1990;17:186-190.
8. Syed SA, Svanberg M, Svanberg G. The predominant cultivable dental plaque flora of beagle dogs with gingivitis. J Periodont Res 1980;15:123-136.
9. Löe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963;21:533-535.
10. Silness J, Löe H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal control. Acta Odontol Scand 1963;22:121-123.
11. Tsuchida K, Hara K. Clinical significance of gingival fluid measurement by "Periotron." J Periodontol 1981;52:697-670.
12. Cutler CW, Wasfy MO, Ghaffar K, Hosni M, Lloyd DR. Impaired bactericidal activity of PMN from two brothers with necrotizing ulcerative gingivo-periodontitis. J Periodontol 1994;65:357-363.
13. Caffesse RG, Kornman KS, Nasjleti CE. The effect of intensive antibacterial therapy on the sulcular environment in monkeys. Part II. Inflammation, mitotic activity and keratinization of the sulcular epithelium. J Periodontol 1980;51:155-161.
14. Slots J, Feik D, Rams TE. In vitro antimicrobial sensitivity of enteric rods and pseudomonads from advanced adult periodontitis. Oral Microbiol Immunol 1990;5:298-301.
15. Hurzeler MB, Quiñones CR, Morrison EC, Caffesse RG. Treatment of peri-implantitis using regeneration and bone grafts, alone or in combination, in beagle dogs. Part I. Clinical findings and histologic observations, Int J Oral Maxillofac Implants 1995;10:474-484.
16. Klinge B, Kuvatanasuhati J, Attstrom R, Kalfas S, Edwardsson S. The effect of topical metronidazole therapy on experimentally-induced periodontitis in the beagle dog. J Clin Periodontol 1992;19: 702-707.
17. Williams RC, Jeffcoat MK, Howell TH, et al. Topical flurbiprofen treatment of periodontitis in beagles. J Periodont Res 1988;23:166-169.
18. Francis JR, Hunter B, Addy M. A comparison of three delivery methods of chlorhexidine in handicapped children. I. Effects on plaque gingivitis and toothstaining. J Periodontol 1987;58:451.
19. Giargia M, Ericsson I, Lindhe J, Beglundh T, Neiderud AM. Tooth mobility and resolution of experimental periodontilis. An experimental study in the dog. J Clin Periodontol 1994;21:457-464.
20. Williams RC, Offenbacher S, Jeffcoat MK, et al. Indomethicin or flurbiprofen treatment of periodontitis in beagles: Effect on crevicular fluid arachidonic acid metabolites compared with effect on bone loss. J Periodont Res 1988;23:134-138.